Abstract: The present disclosure relates to compositions and methods for treating or preventing neonatal herpes simplex virus (HSV) infection and/or the neurological and/or non-neurological sequelae thereof.

Abstract: Methods and system for providing synchronization of a multi-threaded application includes analyzing a source file of the application to identify one or more synchronization annotations contained therein, wherein the synchronization annotations are defined using declarative statements. One or more synchronization annotation processors are identified and invoked for processing the one or more synchronization annotations identified in the source file so as to generate code files. The source file is compiled to generate one or more class files by compiling the procedural code within the source file to generate one or more class files, and compiling the code files to generate the one or more class files. The class files associated with the code files are used by the multiple threads during execution of the application to arbitrate access to methods and data manipulated by classes within the class files associated with the procedural code.

Abstract: Methods and system for providing synchronization of a multi-threaded application includes analyzing a source file of the application to identify one or more synchronization annotations contained therein, wherein the synchronization annotations are defined using declarative statements. One or more synchronization annotation processors are identified and invoked for processing the one or more synchronization annotations identified in the source file so as to generate code files. The source file is compiled to generate one or more class files by compiling the procedural code within the source file to generate one or more class files, and compiling the code files to generate the one or more class files. The class files associated with the code files are used by the multiple threads during execution of the application to arbitrate access to methods and data manipulated by classes within the class files associated with the procedural code.

Abstract: A method and system for providing an efficient and convenient mechanism for class loading is presented. A present system and method virtual machine includes a bulk class loading component, normal class loader and execution engine. The bulk class loading component performs bulk loading of classes in a single pass of respective code sources. The normal class loader performs normal class loading activities, including normal class hierarchy tree searches and single class loading with multiple search traversals. In one embodiment, a bulk class identification component identifies classes for bulk loading. Classes can be identified for bulk class loading based upon designated characteristics or attributes. For example, a designated characteristic can include a class that is loaded between two points in time (e.g., from startup to a predetermined time after startup).

Abstract: Computer assisted detection (CAD) is made accessible to more medical offices. The CAD is provided as a service. Customers gain access to CAD service through a computer network but without the purchase of expensive software and/or hardware. The customers use software for extracting needed patient data to use the CAD service. The CAD service provider uses a server farm or third party server facilities, allowing growth without as substantial upfront costs. The CAD service provider collects patient data by providing the service. The aggregated patient data allows training of different or improved CAD algorithms. The service also identifies suspect data, such as associated with incorrect imaging settings, and provides help to the customers.

Abstract: Computer assisted detection (CAD) is made accessible to more medical offices. The CAD is provided as a service. Customers gain access to CAD service through a computer network but without the purchase of expensive software and/or hardware. The customers use software for extracting needed patient data to use the CAD service. The CAD service provider uses a server farm or third party server facilities, allowing growth without as substantial upfront costs. The CAD service provider collects patient data by providing the service. The aggregated patient data allows training of different or improved CAD algorithms. The service also identifies suspect data, such as associated with incorrect imaging settings, and provides help to the customers.

Abstract: A method and system for providing an efficient and convenient mechanism for class loading is presented. A present system and method virtual machine includes a bulk class loading component, normal class loader and execution engine. The bulk class loading component performs bulk loading of classes in a single pass of respective code sources. The normal class loader performs normal class loading activities, including normal class hierarchy tree searches and single class loading with multiple search traversals. In one embodiment, a bulk class identification component identifies classes for bulk loading. Classes can be identified for bulk class loading based upon designated characteristics or attributes. For example, a designated characteristic can include a class that is loaded between two points in time (e.g., from startup to a predetermined time after startup).

Abstract: A method for authenticating a software library, including inserting an encrypted checksum into a software library, and in response to loading the software library calculating a checksum of the software library, requesting the encrypted checksum from the library, decrypting the encrypted checksum, and checking whether or not the decrypted checksum agrees with the calculated checksum. A system is also described and claimed.

Abstract: A method for authenticating a software library, including inserting an encrypted checksum into a software library, and in response to loading the software library calculating a checksum of the software library, requesting the encrypted checksum from the library, decrypting the encrypted checksum, and checking whether or not the decrypted checksum agrees with the calculated checksum. A system is also described and claimed.

Abstract: A herpes simplex virus (HSV) mutant, UL41NHB, is disclosed which is deficient in the virion host shutoff (vhs) function. This mutant is shown to be profoundly attenuated in its ability to replicate at the periphery and in the nervous system, and in its ability to reactivate from latency.