Patents by Inventor David Lembo

David Lembo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11814366
    Abstract: The present invention relates to compounds of formula (I), their use as medicaments, in particular as broad spectrum antiviral agents, their combination with a further antiviral agent and relative pharmaceutical compositions. In particular, the compounds of the invention are useful in the treatment of a disease caused by an enveloped virus.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: November 14, 2023
    Assignee: UNIVERSITA DEGLI STUDI DI SIENA
    Inventors: Maurizio Botta, Filippo Canducci, Valeria Cagno, David Lembo, Cristina Tintori, Annalaura Brai, Nastasja Palombi
  • Publication number: 20210070737
    Abstract: The present invention relates to compounds of formula (I), their use as medicaments, in particular as broad spectrum antiviral agents, their combination with a further antiviral agent and relative pharmaceutical compositions. In particular, the compounds of the invention are useful in the treatment of a disease caused by an enveloped virus.
    Type: Application
    Filed: March 18, 2019
    Publication date: March 11, 2021
    Applicant: UNIVERSITA DEGLE STUDI DI SIENA
    Inventors: Maurizio BOTTA, Filippo CANDUCCI, Valeria CAGNO, David LEMBO, Cristina TINTORI, Annalaura BRAI, Nastaja PALOMBI
  • Publication number: 20180291057
    Abstract: The present invention relates to oxysterols of formula (I): for use in the treatment of infections caused by a naked virus, in particular a virus selected from the group consisting of rotavirus, papillomavirus and rhinovirus.
    Type: Application
    Filed: January 23, 2018
    Publication date: October 11, 2018
    Inventors: David Lembo, Giuseppe Leone Graziano Enrico Poli, Andrea Civra, Valeria Cagno
  • Publication number: 20170137458
    Abstract: The present invention relates to oxysterols of formula (I) for use in the treatment of infections caused by a naked virus, in particular a virus selected from the group consisting of rotavirus, papillomavirus and rhinovirus.
    Type: Application
    Filed: July 2, 2015
    Publication date: May 18, 2017
    Inventors: David Lembo, Giuseppe Leone Graziano Enrico Poli, Andrea Civra, Valeria Cagno
  • Patent number: 8877738
    Abstract: The present invention relates to monomeric and multimeric peptidic compounds which have antipathogenic, in particular antiviral or/and antibacterial activity. In a preferred aspect, the peptide compounds of the invention have an activity in respect of a broad spectrum of viruses, both DNA and RNA viruses, irrespective of whether they possess virus envelope or not. Further, the present invention refers to compositions comprising said peptidic compounds for medical use, i.e. for the treatment or prevention of pathogenic, in particular viral or/and bacterial infections.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: November 4, 2014
    Assignee: Spiderbiotech S.r.L.
    Inventors: Andrea Giuliani, Giovanna Pirri, Lorena Pizzuto, Santo Landolfo, Giorgio Gribaudo, David Lembo, Davide Gibellini
  • Patent number: 8673849
    Abstract: The present invention relates to monomeric and multimeric peptidic compounds which have antiviral activity, particularly against integrin-using viruses, more particularly against rotavirus. Further, the present invention refers to compositions comprising said peptidic compounds for medical use or for use as food additives.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: March 18, 2014
    Assignee: ROTALACTIS Srl
    Inventors: Amedeo Conti, David Lembo, Claudio Fabris, Enrico Bertino, Santo Landolfo
  • Publication number: 20130243721
    Abstract: Guanidine-based poly (amidoamine) polymers of formula (I): wherein n is an integer between 3 and 400; R1 is H, C1-6 alkyl; or taken together with the N atoms to which is bound and R2 is a piperazinic ring; R2 is C2-6 alkylen; C5-6 cycloalkylen; CH—COOH, CH—COOR, wherein R is C1-4 alkyl, phenyl or benzyl; R3 is —(CH2)p-HN—C (NH2)?NH, wherein p is an integer 1 to 6; for use as antiviral agents in the prevention and/or treatment of viral infections in a mammal, preferably a human subject.
    Type: Application
    Filed: May 3, 2013
    Publication date: September 19, 2013
    Inventors: Paolo Ferruti, Roberta Cavalli, Elisabetta Ranucci, David Lembo
  • Publication number: 20130130970
    Abstract: The present invention relates to monomeric and multimeric peptidic compounds which have antiviral activity, particularly against integrin-using viruses, more particularly against rotavirus. Further, the present invention refers to compositions comprising said peptidic compounds for medical use or for use as food additives.
    Type: Application
    Filed: May 31, 2011
    Publication date: May 23, 2013
    Applicant: ROTALACTIS SRL
    Inventors: Amedeo Conti, David Lembo, Claudio Fabris, Enrico Bertino, Santo Landolfo
  • Publication number: 20120121623
    Abstract: The present invention relates to monomeric and multimeric peptidic compounds which have antipathogenic, in particular antiviral or/and antibacterial activity. In a preferred aspect, the peptide compounds of the invention have an activity in respect of a broad spectrum of viruses, both DNA and RNA viruses, irrespective of whether they possess virus envelope or not. Further, the present invention refers to compositions comprising said peptidic compounds for medical use, i.e. for the treatment or prevention of pathogenic, in particular viral or/and bacterial infections.
    Type: Application
    Filed: August 5, 2010
    Publication date: May 17, 2012
    Applicant: SPIDERBIOTCH S.r.L.
    Inventors: Andrea Giuliani, Giovanna Pirri, Lorena Pizzuto, Santo Landolfo, Giorgio Gribaudo, David Lembo, Davide Gibellini