Abstract: An autonomous vehicle navigates an environment in which occlusions block the vehicle's ability to detect moving objects. The vehicle handles this by receiving sensor data corresponding to the environment, identifying one or more particles of a plurality of initialized particles that have a non-zero probability of being associated with a potential occluded actor in the occluded region, and generating a trajectory of the autonomous vehicle for traversing the environment based on spatiotemporal reasoning about the occluded region and taking into account the one or more particles. Each particle may be associated with a potential actor.

Abstract: An autonomous vehicle navigates an environment in which occlusions block the vehicle's ability to detect moving objects. The vehicle handles this by receiving sensor data corresponding to the environment, identifying one or more particles of a plurality of initialized particles that have a non-zero probability of being associated with a potential occluded actor in the occluded region, and generating a trajectory of the autonomous vehicle for traversing the environment based on spatiotemporal reasoning about the occluded region and taking into account the one or more particles. Each particle may be associated with a potential actor.

Abstract: A method is disclosed for identifying an appropriate parking space for a motor and a route leading thereto for a motor vehicle having a navigation system, wherein at least one collision-free route is calculated on the basis of at least one piece of information that is related to a search for a parking space and that is requested from at least one external server, which manages at least one parking lot having at least one parking space, before the motor vehicle reaches the parking lot. A motor vehicle with a navigation system and an external server, for execution of the method, are also disclosed.

Abstract: A method for operating a navigation system including a vehicle and a computing device outside the vehicle is described. A navigation device on-board the vehicle determines, from route network data transmitted by the computing device and describing route segments of a route network, a route segment sequence. The route segment sequence includes at least one route segment and is used to reach a target position from a start position. The navigation device verifies the traversability of the route segment sequence for the vehicle, taking into account route segment information transmitted by the computing device upon a request of the navigation device, and determines a navigation route derived from a route segment sequence which has been verified to be traversable.

Abstract: A method is disclosed for identifying an appropriate parking space for a motor and a route leading thereto for a motor vehicle having a navigation system, wherein at least one collision-free route is calculated on the basis of at least one piece of information that is related to a search for a parking space and that is requested from at least one external server, which manages at least one parking lot having at least one parking space, before the motor vehicle reaches the parking lot. A motor vehicle with a navigation system and an external server, for execution of the method, are also disclosed.

Abstract: A motor vehicle has a control device to control automated longitudinal and/or transverse guidance of the motor vehicle within the scope of a specific driving maneuver. The motor vehicle also has an operator control element to communicate with the control device and to transfer control information, relating to the at least partially automated longitudinal and/or transverse guidance, to the control device. The control device is configured in such a way that activation or deactivation of the longitudinal and/or transverse guidance can be controlled by means of an operator-side first operator-control action at the operator-control element, and at least one driving parameter which influences the longitudinal and/or transverse guidance of the motor vehicle, controlled by the control device, can be modified by means of an additional operator-side, second operator-control action at the operator-control element, which second operator-control action is in particular different from the first operator-control action.

Abstract: A motor vehicle has a control device to control automated longitudinal and/or transverse guidance of the motor vehicle within the scope of a specific driving maneuver. The motor vehicle also has an operator control element to communicate with the control device and to transfer control information, relating to the at least partially automated longitudinal and/or transverse guidance, to the control device. The control device is configured in such a way that activation or deactivation of the longitudinal and/or transverse guidance can be controlled by means of an operator-side first operator-control action at the operator-control element, and at least one driving parameter which influences the longitudinal and/or transverse guidance of the motor vehicle, controlled by the control device, can be modified by means of an additional operator-side, second operator-control action at the operator-control element, which second operator-control action is in particular different from the first operator-control action.

Abstract: Disclosed herein are methods for the large-scale preparation of human butyrylcholinesterase (HuBChE) preparations from Cohn Fraction IV-4. As disclosed, the methods provide HuBChE preparations that are about 99% or more pure with recovery yields of about 60%. Also disclosed are the pharmacokinetics, safety and toxicity, stability and efficacy of the HuBChE preparations.

Abstract: Disclosed herein are methods for the large-scale preparation of human butyrylcholinesterase (HuBChE) preparations from Cohn Fraction IV-4. As disclosed, the methods provide HuBChE preparations that are about 99% or more pure with recovery yields of about 60%. Also disclosed are the pharmacokinetics, safety and toxicity, stability and efficacy of the HuBChE preparations.

Abstract: A material comprising a porous support and a plurality of enzymes for the removal, decontamination or neutralization of hazardous chemicals such as OP compounds is disclosed. The material may be used on a variety of surfaces, including natural, synthetic and biological surfaces such as skin and other delicate membranes. Also disclosed is a process of making the material, kits and various methods and reactivation devices for reactivating the enzymatic activity of the material.

Abstract: An enzymatically active reusable sponge or foam, capable of regeneration with oximes, made of a polymer such as polyurethane is prepared for detoxification of hazardous compounds such as organophosphorus and organosulfur compounds. The foam or sponge contains a plurality of enzymes including enzymes selected from acetylcholinesterase, butyrylcholinesterase, triesterase, pseudocholinesterase, organophosphate hydrase, phosphotriesterase, paraoxonase and organophosphorus and organosulfur hydrolyzing enzymes. The sponge or foam may additionally contain activated carbon and an enzyme reactivation compound. A kit can be formed containing the sponge or foam and the compound for enzyme reactivation. The enzymatically active foam or sponge may be prepared using a two chamber device where enzymes and prepolymer are passed from separate chambers into a static mixing stator and are subjected to low shear mixing and extrusion to form by the sponge or foam.

Abstract: A material comprising a porous support and a plurality of enzymes for the removal, decontamination or neutralization of hazardous chemicals such as OP compounds is disclosed. The material may be used on a variety of surfaces, including natural, synthetic and biological surfaces such as skin and other delicate membranes. Also disclosed is a process of making the material, kits and various methods and reactivation devices for reactivating the enzymatic activity of the material.

Abstract: Methods, compositions and materials useful in the detection of organophosphorous and organosulfur compounds are disclosed. In particular, biosensors wherein a porous or a non-porous support having an enzyme immobilized upon or within are disclosed. The biosensors exhibit enzymatic stability at extreme temperatures and/or denaturing conditions, and similar kinetic characteristics of the soluble form of the enzymes utilized. The enzyme does not leach from the porous or non-porous support and the material retains enzymatic activity after prolonged storage. Differential biosensors are also disclosed.