Patents by Inventor David Lerner

David Lerner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050228903
    Abstract: The present disclosure includes systems and techniques relating to booting to a network storage target. In general, in one implementation, a bus-to-network device driver is loaded during a machine boot, where the bus-to-network device driver is capable of sending machine bus commands over a network, providing access to the network for a network device driver, and distinguishing between received responses to the machine bus commands and other network traffic corresponding to the network device driver. Loading of the bus-to-network device driver can occur in response to an operating system load of bus drivers. For example, the bus-to-network device driver can be an iSCSI driver, and the operating system load of bus drivers can be the operating system load of SCSI drivers.
    Type: Application
    Filed: April 8, 2004
    Publication date: October 13, 2005
    Inventors: David Lerner, Dave Matheny, Douglas Boom
  • Publication number: 20050197590
    Abstract: A system (10) analyzes signals representative of a subject's brain activity in a signal processor (12) for information indicating the subject's current activity state and for predicting a change in the activity state. One preferred embodiment uses a combination of nonlinear filtering methods to perform real-time analysis of the electro-encephalogram (EEG) or electro-corticogram (ECoG) signals from a subject patient for information indicative of or predictive of a seizure, and to complete the needed analysis at least before clinical seizure onset. The preferred system then performs an output task for prevention or abatement of the seizure, or for recording pertinent data.
    Type: Application
    Filed: August 1, 2002
    Publication date: September 8, 2005
    Inventors: Ivan Osorio, Mark Frei, David Lerner, John Ralston, Josef Dorfmeister
  • Publication number: 20050197365
    Abstract: The subject invention provides a compound having the structure: wherein Y is O, NR3R4 or NOR6; R3 is H, alkyl, aralkyl, alkynyl, trifluoroacetyl, t-butoxycarbonyl or an acyl group; R4 is H, alkyl, aralkyl, or alkynyl; R6 is H or C1-C4 alkyl; R1 and R2 are each independently H, alkyl, aralkyl, or alkynyl; the curved line drawn from S to the center of the phenyl ring and the straight line drawn from N to the center of the ring indicate that S and N are part of a 5 membered ring which shares two carbons with the phenyl ring; and the dashed line drawn from the carbon atom on the cyclopentyl ring to Y represents a bond when Y is O or NOR6 and is absent when Y is NR3R4, and wherein wherein X is H or O; and R5 is H, alkyl, trifluoroacetyl, t-butoxycarbonyl or an acyl group, or an enantiomer, or a tautomer, or a pharmaceutically acceptable salt thereof, a process for preparing the compounds and a method of treating Parknison's disease, multiple sclerosis or depression with the compounds of the invention.
    Type: Application
    Filed: February 25, 2005
    Publication date: September 8, 2005
    Inventors: Jeffrey Sterling, Liat Hayardeny-Nisimov, David Lerner, Yaacov Herzig, Eliezer Falb, Gyorgy Toth, Sandor Molnar, Dalia Pinkert
  • Publication number: 20040176430
    Abstract: The subject invention provides compounds having the structure: 1
    Type: Application
    Filed: November 20, 2003
    Publication date: September 9, 2004
    Inventors: Jeffrey Sterling, Liat Hayardeny, Eliezer Falb, Yaacov Herzig, David Lerner
  • Patent number: 6740042
    Abstract: A system and method for simultaneous, bilateral, segmental blood pressure measurement are disclosed. In one illustrative embodiment of the invention, two Doppler modules are configured to operate at nominally the same Doppler carrier frequency so that they probe for substantially the same range of physiological information. However, the Doppler carrier frequencies for the Doppler modules are also sufficiently different to substantially avoid interference between the two modules. A phase-locked loop (PLL) used to demodulate the velocity signals in each Doppler module efficiently blocks interference signals because they have frequencies that are the difference in the Doppler carrier frequencies and that are outside the locking range of the PLL. Broad-band RF amplifiers and Doppler transducers are used to ensure that the frequency responses of the Doppler modules are substantially the same.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: May 25, 2004
    Assignee: Biomedix, Inc.
    Inventors: David A. Lerner, William Lee Rogers
  • Publication number: 20030212145
    Abstract: The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also provides methods of treating a subject afflicted with Parkinson's disease, a memory disorder, dementia, depression, hyperactive syndrome, an effective illness, a neurodegenerative disease, a neurotoxic injury, stroke, brain ischemia, a head trauma injury, a spinal trauma injury, neurotrauma, schizophrenia, an attention deficit disorder, multiple sclerosis, or withdrawal symptoms, using R(+)-N-propargyl-1-aminoindan or the pharmaceutically acceptable salt of the subject invention. The subject invention further provides a method of preventing nerve damage in a subject. Finally, the subject invention provides methods of preparing R(+)-N-propargyl-1-aminoindan, a salt thereof, and racemic N-propargyl-1-aminoindan.
    Type: Application
    Filed: November 27, 2002
    Publication date: November 13, 2003
    Applicants: Teva Pharmaceutical Industries, Ltd., Technion Research Development Foundation, Ltd.
    Inventors: Moussa B.H. Youdim, John P.M. Finberg, Ruth Levy, Jeffrey Sterling, David Lerner, Haim Yellin, Alex Veinberg
  • Patent number: 6549804
    Abstract: A system (10) analyzes signals representative of a subject's brain activity in a signal processor (12) for information indicating the subject's current activity state and for predicting a change in the activity state. One preferred embodiment uses a combination of nonlinear filtering methods to perform real-time analysis of the electro-encephalogram (EEG) or electro-corticogram (ECoG) signals from a subject patient for information indicative of or predictive of a seizure, and to complete the needed analysis at least before clinical seizure onset. The preferred system then performs an output task for prevention or abatement of the seizure, or for recording pertinent data.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: April 15, 2003
    Assignee: University of Kansas
    Inventors: Ivan Osorio, Mark Frei, David Lerner, John Ralston, Josef Dorfmeister
  • Publication number: 20030069738
    Abstract: A method and system for use by a Customs Agency for clearing shipments of goods into a country is disclosed. A customs resource application may be used to integrate alert information, news, research, and communications capabilities. Customs inspectors may use the resource application with a conventional computer, or with a portable device in the field as they perform customs inspections. The portable device provides access to alert information regarding shipments that are to be inspected by the inspector, and provides alert resolution capabilities so that the inspector can clear shipments into the country from the location of the inspection and/or shipped goods without requiring the inspector to return to a field office to clear the goods.
    Type: Application
    Filed: October 5, 2001
    Publication date: April 10, 2003
    Inventors: Lynn Ann Casey, Stephen David Lerner
  • Publication number: 20020097478
    Abstract: A beam steering module comprised of a mirror stack array in close proximity to a collimator array controllably steers photons along two axis and in a direction substantially less than 90 degrees to the collimator orientation. Several configurations of the module are described using single and double axis mirror rotation and relay optics. Optical telecommunications switches are shown using modules coupled to each other along flat and curved surfaces, with and without use of fold mirror and enabling a plurality of configuration options including photodetector optical power monitoring schemes that require no external power taps.
    Type: Application
    Filed: March 17, 2001
    Publication date: July 25, 2002
    Inventors: Behrang Behin, Robert Conant, Michael J. Daneman, David Horsley, Meng-Hsiung Kiang, David Lerner, Satinderpall Pannu
  • Patent number: 6316504
    Abstract: The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing the same. The subject invention also provides methods of treating a subject afflicted with Parkinson's disease, a memory disorder, dementia, depression, hyperactive syndrome, an affective illness, a neurodegenerative disease, a neurotoxic injury, stroke, brain ischemia, a head trauma injury, a spinal trauma injury, neurotrauma, schizophrenia, an attention deficit disorder, multiple sclerosis, or withdrawal symptoms, using R(+)-N-propargyl-1-aminoindan or the pharmaceutically acceptable salt of the subject invention. The subject invention further provides a method of preventing nerve damage in a subject.
    Type: Grant
    Filed: November 16, 1998
    Date of Patent: November 13, 2001
    Assignees: Technion Research and Development Foundation, Ltd., Teva Pharmaceuticals Industries, Ltd.
    Inventors: Moussa B. H. Youdim, John P. M. Finberg, Ruth Levy, Jeffrey Sterling, David Lerner, Haim Yellin, Alex Veinberg
  • Patent number: 5995868
    Abstract: A system (10) analyzes signals representative of a subject's brain activity in a signal processor (12) for information indicating the subject's current activity state and for predicting a change in the activity state. One preferred embodiment uses a combination of nonlinear filtering methods to perform real-time analysis of the electro-encephalogram (EEG) or electro-corticogram (ECoG) signals from a subject patient for information indicative of or predictive of a seizure, and to complete the needed analysis at least before clinical seizure onset. The preferred system then performs an output task for prevention or abatement of the seizure, or for recording pertinent data.
    Type: Grant
    Filed: January 6, 1997
    Date of Patent: November 30, 1999
    Assignee: University of Kansas
    Inventors: Josef Dorfmeister, Mark Frei, David Lerner, Ivan Osorio, John Ralston
  • Patent number: 5786390
    Abstract: The subject invention relates to pharmaceutical composition of R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 28, 1998
    Assignees: Teva Pharmaceutical Industries Ltd., Technion Research and Development Foundation Ltd.
    Inventors: Moussa B. H. Youdim, John P. M. Finberg, Ruth Levy, Jeffrey Sterling, David Lerner, Tirtsah Berger-Paskin, Haim Yellin, Alex Veinberg
  • Patent number: 5752235
    Abstract: A device for monitoring medication of a patient and for prompting the patient into certain medication taking schedule and/or certain programming steps and routines. The device has a plurality of compartments, each of which may store medication, and an electrical signaling system to emit medication alert signals from time-to-time, each of which said signals indicates (a) that medication should be taken, (b) from which compartment the medication should be taken, (c) and the quantity of medication to be taken. If a designated compartment is not opened and closed within a predetermined period of time, the electrical signaling system will display an alarm and the event will be recorded as a missed medication event, unless the patient then opens the designated compartment. If each designated compartment is opened and closed, the take-medication signal and the alarm (if operating) are turned off and the event is recorded for later review.
    Type: Grant
    Filed: July 23, 1990
    Date of Patent: May 12, 1998
    Assignee: InforMedix, Inc.
    Inventors: Bruce A. Kehr, David Lerner, Richard D. Demenus, Michael J. Edl
  • Patent number: 5744500
    Abstract: The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also provides methods of treating a subject afflicted with Parkinson's disease, a memory disorder, dementia, depression, hyperactive syndrome, an affective illness, a neurodegenerative disease, a neurotoxic injury, stroke, brain ischemia, a head trauma injury, a spinal trauma injury, neurotrauma, schizophrenia, an attention deficit disorder, multiple sclerosis, or withdrawal symptoms, using R(+)-N-propargyl-1-aminoindan or the pharmaceutically acceptable salt of the subject invention. The subject invention further provides a method of preventing nerve damage in a subject. Finally, the subject invention provides methods of preparing R(+)-N-propargyl-1-aminoindan, a salt thereof, and racemic N-propargyl-1-aminoindan.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: April 28, 1998
    Assignees: Teva Pharmaceutical Industries, Ltd., Technion Research and Development Foundation Ltd.
    Inventors: Moussa B. H. Youdim, John P. M. Finberg, Ruth Levy, Jeffrey Sterling, David Lerner, Haim Yellin, Alex Veinberg
  • Patent number: 5668181
    Abstract: This invention relates to the use of R(+)-N-propargyl-1-aminoindan.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: September 16, 1997
    Assignees: Teva Pharmaceutical Industries Ltd., Techion Research and Development Foundation Ltd.
    Inventors: Moussa B. H. Youdim, John P. M. Finberg, Ruth Levy, Jeffrey Sterling, David Lerner, Tirtsah Berger-Paskin, Haim Yellin
  • Patent number: 5646188
    Abstract: A compound of general formula I ##STR1## wherein n is 1 or 2; R.sub.1 and R.sub.2 are each independently hydrogen, hydroxy, substituted or unsubstituted C.sub.1-4 alkyl, substituted or unsubstituted C.sub.1-4 alkoxy or halogeno;R.sub.5 is hydrogen, substituted or unsubstituted C.sub.1-4 alkyl, amino or NR.sub.6 R.sub.7 ;R.sub.3, R.sub.4, R.sub.6 and R.sub.7 are each independently hydrogen or (CH.sub.2).sub.m --[NH(CH.sub.2).sub.x ].sub.y --NHR.sub.11 wherein m is from 0-5, y is from 0-5 and each x is independently from 1-5 and R.sub.11 is hydrogen or C(NH)NH.sub.2 ;provided that when R.sub.3 and R.sub.4 are both hydrogen, R.sub.5 is amino or NR.sub.6 R.sub.7 ; pharmaceutically acceptable salts and optically active isomers thereof.
    Type: Grant
    Filed: July 5, 1995
    Date of Patent: July 8, 1997
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Gad Gilad, Varda Gilad, Jeffrey Sterling, Yaacov Herzig, David Lerner, Alex Veinberg, Isaac Milman, Nina Finkelstein
  • Patent number: 5599991
    Abstract: The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also provides methods of treating a subject afflicted with Parkinson's disease, a memory disorder, dementia, depression, hyperactive syndrome, an affective illness, a neurodegenerative disease, a neurotoxic injury, brain ischemia, a head trauma injury, a spinal trauma injury, schizophrenia, an attention deficit disorder, multiple sclerosis, or withdrawal symptoms, using R(+)-N-propargyl-1-aminoindan or the pharmaceutically acceptable salt of the subject invention. The subject invention further provides a method of preventing nerve damage in a subject. Finally, the subject invention provides methods of preparing R(+)-N-propargyl-1-aminoindan, a salt thereof, and racemic N-propargyl-1-aminoindan.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 4, 1997
    Assignees: Teva Pharmaceutical Industries Ltd., Technion Research and Development Foundation, Ltd.
    Inventors: Moussa B. H. Youdim, John P. M. Finberg, Ruth Levy, Jeffrey Sterling, David Lerner, Haim Yellin, Alex Veinberg
  • Patent number: 5585358
    Abstract: A compound having the structure: ##STR1## wherein R.sub.1, R.sub.2, and R.sub.3 are independently the same or different and are hydrogen, a C.sub.1 -C.sub.6 alkyl group, an aralkyl group, or an aryl group, and n is an integer which is greater than or equal to 0 and less than or equal to 3. Also provided are a compound containing a 2-valproenoic moiety, pharmaceutical compositions comprising these compounds, and methods of using them for the effective treatment of epilepsy and other neurological disorders.
    Type: Grant
    Filed: July 6, 1993
    Date of Patent: December 17, 1996
    Assignees: Yissum Research Development Corporation of the Hebrew University of Jerusalem, Teva Pharmaceutical Industries Ltd.
    Inventors: Meir Bialer, Salim Hadad, Jacob Herzig, Jeff Sterling, David Lerner, Mitchell Shirvan
  • Patent number: 5562098
    Abstract: An ultrasonic blood flow velocimeter for measuring the velocity of blood flowing in an artery or vein beneath the skin of a patient, by insonating the tissue with ultrasonic energy, receiving doppler-shifted signals reflected by the blood and processing the signals to determine blood velocity. The signal processing and calculations result in an accurate measure of velocity which is independent of the angle between the probe and the blood flow. This gives more accurate results than other ultrasonic methods which approximate results because of angle dependency and the fact that in general this angle is unknown. The invention can also detect and discriminate between forward and reverse flows, even when they occur simultaneously, as in the case of insonating an artery and vein with opposite flows. The invention can also measure peak flow velocity, though efficient time domain processing of signals.
    Type: Grant
    Filed: March 20, 1995
    Date of Patent: October 8, 1996
    Assignee: LifeSigns Corporation
    Inventor: David A. Lerner
  • Patent number: 5532415
    Abstract: The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also provides methods of treating a subject afflicted with Parkinson's disease, a memory disorder, dementia, depression, hyperactive syndrome, an affective illness, a neurodegenerative disease, a neurotoxic injury, brain ischemia, a head trauma injury, a spinal trauma injury, schizophrenia, an attention deficit disorder, multiple sclerosis, or withdrawal symptoms, using R(+)-N-propargyl-1-aminoindan or the pharmaceutically acceptable salt of the subject invention. The subject invention further provides a method of preventing nerve damage in a subject. Finally, the subject invention provides methods of preparing R(+)-N-propargyl-1-aminoindan, a salt thereof, and racemic N-propargyl-1-aminoindan.
    Type: Grant
    Filed: March 28, 1995
    Date of Patent: July 2, 1996
    Assignees: Teva Pharmaceutical Industries Ltd., Technion Research and Development Foundation Ltd.
    Inventors: Moussa B. H. Youdim, John P. M. Finberg, Ruth Levy, Jeffrey Sterling, David Lerner, Tirtsah Berger-Paskin, Haim Yellin, Alex Veinberg