Abstract: A method comprising capturing at least one image of a cervical tissue in-vivo; identifying a region of interest (ROI) in said cervical tissue within said at least one image; detecting at least a portion of a vaginal speculum within said at least one image; and determining a position of said portion of said vaginal speculum relative to said ROI.

Abstract: A method for detecting tissue abnormality in a tissue sample, comprising: illuminating a tissue sample in vivo with a first light beam having a wavelength selected from the range 390-430 nanometer (nm); applying contrast agent to the tissue sample; capturing a one or more images of the tissue sample; and detecting tissue abnormality based on at least one of color changes in the tissue sample and blood vessel features in the tissue sample appearing in said one or more images.

Abstract: A method for automated image capture of a body tissue in situ, comprising: providing an imaging device configured to transmit an image stream of a body tissue; and using at least one hardware processor for: receiving the image stream, identifying a medical accessory appearing in the image stream, and capturing multiple images of the body tissue, wherein (i) at least one of the images is captured before said identifying, and (ii) at least one of the images is captured at one or more specified times upon said identifying.

Abstract: A system including: a mobile device, including: a camera configured to capture multiple images of a subject; a processor configured to identify a first image of the captured images as a blue frame, wherein the image was captured while the subject was illuminated by blue light, and identify a second image of one of the captured images as a white frame, wherein the image was captured while the subject was illuminated by white light; associate the blue frame with the white frame; detect a feature depicted in the blue frame that is not depicted in the associated white frame, and indicate the detection of the feature to a user; and a user interface display configured to separately render the blue frame and the white frame.

Abstract: A multi-modal imaging and optical property measurement device that is integrated into an interferometer. Data acquired by the multiple imaging modalities in parallel include measurements of single-scattered, multiple-scattered, and diffuse light that enable characterization of different ranges within different depth regions in the sample. The system includes different interferometer configurations and different imaging modalities, and has a signal-processing unit that associates and co-registers interferometric, multi-spectral, and polarization sensitive measurements to derive and analyze optical properties of a sample and enhance an image display of the sample.

Abstract: A system comprising: a mobile device, comprising: a camera configured to capture multiple images of a subject; a processor configured to identify a first image of the captured images as a blue frame, wherein the image was captured while the subject was illuminated by blue light, and identify a second image of one of the captured images as a white frame, wherein the image was captured while the subject was illuminated by white light; associate the blue frame with the white frame; detect a feature depicted in the blue frame that is not depicted in the associated white frame, indicate the detection of the feature to a user; and a user interface display configured to separately render the blue frame and the white frame.

Abstract: A polarized light imaging apparatus for separating light from a superficial single-scattering layer of a sample and its deeper diffuse layer as a function of space is disclosed. The apparatus has a light source for producing light beams; an illumination optic coupled to the light source for guiding the light beams towards the sample; a linear polarizer coupled to the illumination optic; a non-total internal reflection (TIR) birefringent polarizing prism (BPP) communicatively coupled to the sample to maximize a refraction difference between ordinary waves and extraordinary waves of light returning from the sample; and a detection optic unit coupled to the non-TIR BPP for guiding the light waves returning from the sample towards a single polarization sensitive sensor element.

Abstract: A polarized light imaging apparatus is provided. In an embodiment, the apparatus comprises a light source for producing light beams; an illumination optic coupled to the light source for guiding the light beams towards the sample; a linear polarizer coupled to the illumination optic and configured to produce a linearly polarized light towards the sample respective of the light beams; a TIR birefringent polarizing prism (BPP) coupled to the sample to maximize a refraction difference between ordinary waves and extraordinary waves of light returning from the sample; and a detection optic unit coupled to the non-TIR BPP for guiding the light waves returning from the sample towards a single polarization sensitive sensor element (SE), the SE is configured to capture at least one frame of the sample respective of the light waves returning from the superficial single-scattering layer of the sample apart from the deeper diffuse layer.

Abstract: A polarized light imaging apparatus is provided. In an embodiment, the apparatus comprises a light source for producing light beams; an illumination optic coupled to the light source for guiding the light beams towards the sample; a linear polarizer coupled to the illumination optic and configured to produce a linearly polarized light towards the sample respective of the light beams; a TIR birefringent polarizing prism (BPP) coupled to the sample to maximize a refraction difference between ordinary waves and extraordinary waves of light returning from the sample; and a detection optic unit coupled to the non-TIR BPP for guiding the light waves returning from the sample towards a single polarization sensitive sensor element (SE), the SE is configured to capture at least one frame of the sample respective of the light waves returning from the superficial single-scattering layer of the sample apart from the deeper diffuse layer.

Abstract: A multi-modal imaging and optical property measurement device that is integrated into an interferometer. Data acquired by the multiple imaging modalities in parallel include measurements of single-scattered, multiple-scattered, and diffuse light that enable characterization of different ranges within different depth regions in the sample. The system includes different interferometer configurations and different imaging modalities, and has a signal-processing unit that associates and co-registers interferometric, multi-spectral, and polarization sensitive measurements to derive and analyze optical properties of a sample and enhance an image display of the sample.