Patents by Inventor David Lewinsohn

David Lewinsohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising soluble HLA/M. tuberculosis-specific ligand complexes and methods of production and use thereof
    Patent number: 10857219
    Abstract: Compositions that include one isolated, class I HLA-E trimolecular complex that includes a peptide ligand unique to M. tuberculosis-infected cells are disclosed. Isolated compositions that include the three components of the trimolecular complex and/or a polynucleotide encoding one or more of the three components are also disclosed.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: December 8, 2020
    Assignees: The Board of Regents of the University of Oklahoma, Oregon Health & Science University, The United States Government as Represented by the Department of Veterans Affairs
    Inventors: William H. Hildebrand, Curtis McMurtrey, David Lewinsohn, Deborah Lewinsohn, Melanie Harriff
  • Small molecules that bind MR1
    Patent number: 10457682
    Abstract: Disclosed are small molecules and pharmaceutical compositions comprising them that can be used in treating diseases associated with the major histocompatibility complex (MHC) molecule MR1.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: October 29, 2019
    Inventors: David Lewinsohn, Melanie Harriff, Aaron Nilsen, Haihong Jin, Erin Adams, Cara Froyd, Curtis McMurtrey, William Hildebrand
  • SMALL MOLECULES THAT BIND MR1
    Publication number: 20180273536
    Abstract: Disclosed are small molecules and pharmaceutical compositions comprising them that can be used in treating diseases associated with the major histocompatibility complex (MHC) molecule MR1.
    Type: Application
    Filed: October 20, 2017
    Publication date: September 27, 2018
    Applicants: OREGON HEALTH & SCIENCE UNIVERSITY, HE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: David Lewinsohn, Melanie Harriff, Aaron Nilsen, Haihong Jin, Erin Adams, Cara Froyd, Curtis McMurtrey, William Hildebrand
  • Compositions Comprising Soluble HLA/M. Tuberculosis-Specific Ligand Complexes and Methods of Production and Use Thereof
    Publication number: 20150273039
    Abstract: Compositions that include at least one isolated, class I HLA trimolecular complex that includes a peptide ligand unique to M. tuberculosis-infected cells are disclosed. Isolated compositions that include the three components of the trimolecular complex and/or a polynucleotide encoding one or more of the three components are also disclosed.
    Type: Application
    Filed: March 27, 2015
    Publication date: October 1, 2015
    Inventors: William H. Hildebrand, Curtis McMurtrey, David Lewinsohn, Deborah Lewinsohn, Melanie Harriff
  • Methods for producing an immune response to tuberculosis
    Patent number: 8440206
    Abstract: Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb, or treating an infection with Mtb. Pharmaceutical compositions for the prevention and/or treatment of tuberculosis are also disclosed.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: May 14, 2013
    Assignees: Oregon Health & Science University, The United States of America, as represented by the Department of Veteran Affairs
    Inventors: David Lewinsohn, Deborah Lewinsohn
  • METHODS FOR PRODUCING AN IMMUNE RESPONSE TO TUBERCULOSIS
    Publication number: 20120107341
    Abstract: Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb, or treating an infection with Mtb. Pharmaceutical compositions for the prevention and/or treatment of tuberculosis are also disclosed.
    Type: Application
    Filed: December 20, 2011
    Publication date: May 3, 2012
    Inventors: David Lewinsohn, Deborah Lewinsohn
  • Methods for producing an immune response to tuberculosis
    Patent number: 8101192
    Abstract: Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb, or treating an infection with Mtb. Pharmaceutical compositions for the prevention and/or treatment of tuberculosis are also disclosed.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: January 24, 2012
    Assignees: Oregon Health & Science University, The United States of America as represented by the Department of Veterans Affairs
    Inventors: David Lewinsohn, Deborah Lewinsohn
  • METHODS FOR PRODUCING AN IMMUNE RESPONSE TO TUBERCULOSIS
    Publication number: 20110014224
    Abstract: Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb, or treating an infection with Mtb. Pharmaceutical compositions for the prevention and/or treatment of tuberculosis are also disclosed.
    Type: Application
    Filed: September 29, 2010
    Publication date: January 20, 2011
    Inventors: David Lewinsohn, Deborah Lewinsohn
  • Methods for producing an immune response to tuberculosis
    Patent number: 7842299
    Abstract: Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb, or treating an infection with Mtb. Pharmaceutical compositions for the prevention and/or treatment of tuberculosis are also disclosed.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: November 30, 2010
    Assignees: Oregon Health & Science University, The United States of America as represented by the Department of Veterans Affairs
    Inventors: David Lewinsohn, Deborah Lewinsohn
  • METHODS FOR PRODUCING AN IMMUNE RESPONSE TO TUBERCULOSIS
    Publication number: 20090124549
    Abstract: Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb, or treating an infection with Mtb. Pharmaceutical compositions for the prevention and/or treatment of tuberculosis are also disclosed.
    Type: Application
    Filed: March 14, 2007
    Publication date: May 14, 2009
    Inventors: David Lewinsohn, Deborah Lewinsohn