Patents by Inventor David Lewis

David Lewis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260201938
    Abstract: Endless belts, such as for use with e-bikes and other personal mobility systems such as standard bicycles, wheelchairs, scooters including electric scooters, and other systems that utilize a belt for transmitting power to impart motion to the system. The belts are particularly suited for inhibiting “tooth jumping” during use, having a curvature coefficient of no more than 0.01%, and in some embodiments less than 0.005%, with a compressibility coefficient of no more than 0.00075. The belts can utilize reinforcing cords, such as carbon cords, which when incorporated into the final belt, some cords have an open porosity of 10 vol-% or less, in some embodiments 5 vol-% or less.
    Type: Application
    Filed: March 13, 2026
    Publication date: July 16, 2026
    Inventors: Thomas S. MOSS, III, Kyle SPRING, Scott IRVING, David LEWIS
  • Publication number: 20260193651
    Abstract: Disclosed herein are compositions comprising an oligonucleotide that targets MTRES1. The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating conditions associated with MTRES1 gene mutations that include providing an oligonucleotide that targets MTRES1 in a subject.
    Type: Application
    Filed: November 30, 2023
    Publication date: July 9, 2026
    Inventors: Omri GOTTESMAN, Emma BRANDT, Shannon BRUSE, Paul BUSKE, Eric BUSS, Brian CAJES, David JAKUBOSKY, David LEWIS, Gregory MCINNES, David ROZEMA, John VEKICH, Darren H. WAKEFIELD
  • Patent number: 12674165
    Abstract: Provided are compositions comprising an oligonucleotide that targets Angiopoietin-like 4 (ANGPTL4). The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating a metabolic or cardiovascular disorder by providing an oligonucleotide that targets ANGPTL4 to a subject in need thereof.
    Type: Grant
    Filed: May 4, 2022
    Date of Patent: July 7, 2026
    Assignee: EMPIRICO INC.
    Inventors: Omri Gottesman, Shannon Bruse, Brian Cajes, David Lewis, David Rozema
  • Publication number: 20260176623
    Abstract: Molecules for inhibiting arachidonate 15-lipoxygenase (ALOX-15) gene products including dsRNA (dsRNA) agents such as small interfering RNAs (siRNAs) for therapeutic use, additionally, methods to inhibit the expression of a target gene by administering these agents for the treatment of diseases involving ALOX-15 gene products.
    Type: Application
    Filed: February 7, 2025
    Publication date: June 25, 2026
    Inventors: Omri GOTTESMAN, Shannon BRUSE, Brian CAJES, David LEWIS, David ROZEMA
  • Publication number: 20260129444
    Abstract: Terminal devices can request and receive authorization to transmit on the same channel for which a serving base station that can serve the terminal devices has authorization to transmit. Upon transmit authorization or termination being received from a spectrum administration system, the base station can autonomously update the system information it broadcasts. Thus, terminal devices connected to the serving base station can be informed about the channel on which the terminal device should request authorization to transmit.
    Type: Application
    Filed: January 5, 2026
    Publication date: May 7, 2026
    Applicant: AT&T Intellectual Property I, LP.
    Inventors: David Lewis, Vazrik Hovsepian, Spyridon Kapoulas, Rajeev Jayaram
  • Publication number: 20260091053
    Abstract: Provided are compositions comprising an oligonucleotide that targets Thymic stromal lymphopoietin (TSLP). The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating an airway disorder by providing an oligonucleotide that targets TSLP to a subject in need thereof. In some embodiments, the oligonucleotide targeting is specific for a long isoform of TSLP (lfTSLP).
    Type: Application
    Filed: May 19, 2025
    Publication date: April 2, 2026
    Inventors: Omri GOTTESMAN, Shannon BRUSE, Brian CAJES, David LEWIS, David ROZEMA
  • Publication number: 20260065705
    Abstract: A machine translation of a document is created via a compilation of services by mapping textual content from an image to create a plurality of mapped locations correspondent to at least one object from the image, populating each of the mapped locations with at least one character indicative of the object, each character sharing at least one similar attribute, adding to the image the populated mapped locations, and highlighting at least a portion of the textual content in accordance with the populated at least one character. A compilation of services is provided for identifying, extracting, and assessing electronic images by using a layered approach that reduces time and improves reviewing of medical records and other kinds of documentation.
    Type: Application
    Filed: November 4, 2025
    Publication date: March 5, 2026
    Inventor: David Lewis
  • Publication number: 20260055410
    Abstract: Disclosed herein are compositions comprising an oligonucleotide that targets MST1. The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating conditions associated with MST1 mutations that include providing an oligonucleotide that targets MST1 to a subject.
    Type: Application
    Filed: March 12, 2025
    Publication date: February 26, 2026
    Inventors: Omri GOTTESMAN, Shannon BRUSE, Paul BUSKE, Brian CAJES, David JAKUBOSKY, Sarah KLEINSTEIN, David LEWIS, David ROZEMA, John VEKICH
  • Publication number: 20260022554
    Abstract: This invention relates to novel insulation and weather-resistant barrier systems, such as insulated sheathing (IS) panels sheathing panels, and more particularly insulated wall-sheathing (IWS) panels, a panel assembly comprising such panels, and systems for use in construction, such as building construction, designed to provide moisture permeable panels that protect from bulk water, excess air, and thermal transfer. More specifically, this invention relates such panel used for construction purposes, comprising an insulation layer; a structurally-stable panel, an optional fastener-gasketing adhesive layer; and a weather-resistive barrier layer; wherein, in one embodiment, the weather-resistive barrier (WRB) layer exceeds the dimension of the structurally-stable panel from at least one of its edges to create an extension flap; and wherein the extension flap of the WRB layer further comprises a removably attached release-liner on its back.
    Type: Application
    Filed: July 1, 2025
    Publication date: January 22, 2026
    Inventors: Divya Chopra, Rajesh Guntupalli, David Lewis, Thomas Savoy, John Dobson
  • Patent number: 12532169
    Abstract: Terminal devices can request and receive authorization to transmit on the same channel for which a serving base station that can serve the terminal devices has authorization to transmit. Upon transmit authorization or termination being received from a spectrum administration system, the base station can autonomously update the system information it broadcasts. Thus, terminal devices connected to the serving base station can be informed about the channel on which the terminal device should request authorization to transmit.
    Type: Grant
    Filed: October 25, 2022
    Date of Patent: January 20, 2026
    Assignee: AT&T Intellectual Property I, L.P.
    Inventors: David Lewis, Vazrik Hovsepian, Spyridon Kapoulas, Rajeev Jayaram
  • Publication number: 20250370711
    Abstract: A device, such as a multiplying accumulator or at-memory or single instruction, multiple data (SIMD) processing element, is configured to receive numbers defined by an encoding that specifies mantissa and exponent. A product of the mantissas is computed. The product is left shifter by a sum of the exponents and a selectable shift to obtain a left-shifted product. The selectable shift may be based on a selectable radix point, exponent biases, and a maximum mantissa product bitlength. Products may be accumulated. Left-shifted product, whether an intermediate or final result, may be right-shifter by a number of bits that is based on the maximum mantissa product bitlength.
    Type: Application
    Filed: October 24, 2024
    Publication date: December 4, 2025
    Inventors: William Martin Snelgrove, Andrew Vincent Rock, David Lewis, Lui Ray Lam, Jonathan Andrew Scobbie
  • Patent number: 12469320
    Abstract: A machine translation of a document is created via a compilation of services by mapping textual content from an image to create a plurality of mapped locations correspondent to at least one object from the image, populating each of the mapped locations with at least one character indicative of the object, each character sharing at least one similar attribute, adding to the image the populated mapped locations, and highlighting at least a portion of the textual content in accordance with the populated at least one character. A compilation of services is provided for identifying, extracting, and assessing electronic images by using a layered approach that reduces time and improves reviewing of medical records and other kinds of documentation.
    Type: Grant
    Filed: April 2, 2024
    Date of Patent: November 11, 2025
    Assignee: Digital Legal Medical Records, LLC
    Inventor: David Lewis
  • Publication number: 20250333732
    Abstract: Disclosed herein are compositions comprising an oligonucleotide that targets SOS Ras/Rho guanine nucleotide exchange factor 2 (SOS2). The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating conditions associated with SOS2 mutations that include providing an oligonucleotide that targets SOS2 to a subject.
    Type: Application
    Filed: May 23, 2023
    Publication date: October 30, 2025
    Inventors: Omri GOTTESMAN, Shannon BRUSE, Brian CAJES, David LEWIS, David JAKUBOSKY, Gregory MCINNES, David ROZEMA, John VEKICH
  • Publication number: 20250327127
    Abstract: Disclosed herein are compositions comprising a small molecule that targets MTRES1. Also provided herein are methods of treating conditions associated with MTRES1 gene mutations that include providing a small molecule that targets MTRES1 in a subject.
    Type: Application
    Filed: October 23, 2023
    Publication date: October 23, 2025
    Inventors: Omri GOTTESMAN, Emma BRANDT, Shannon BRUSE, Paul BUSKE, Brian CAJES, David JAKUBOSKY, David LEWIS, Gregory MCINNES, David ROZEMA, John VEKICH
  • Publication number: 20250313841
    Abstract: Disclosed herein are compositions comprising an oligonucleotide that targets MST1. The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating conditions associated with MST1 variants that include providing an oligonucleotide that targets MST1 to a subject.
    Type: Application
    Filed: April 3, 2025
    Publication date: October 9, 2025
    Inventors: Omri GOTTESMAN, Shannon BRUSE, Paul BUSKE, Brian CAJES, David JAKUBOSKY, Sarah KLEINSTEIN, David LEWIS, David ROZEMA, John VEKICH
  • Publication number: 20250250568
    Abstract: Disclosed herein are compositions comprising modified oligonucleotides. In some embodiments, the oligonucleotide includes a hydrophobic moiety. In some embodiments, the oligonucleotide includes a vinyl phosphonate. In some embodiments, the oligonucleotide includes modified oligonucleotide sugars such as 2? modified ribose molecules. In some embodiments, the oligonucleotide includes modified internucleoside linkages such as phosphorothioate linkages. In some embodiments, the oligonucleotide includes an siRNA. In some embodiments, the siRNA comprises a duplex region with overhangs on either end.
    Type: Application
    Filed: February 4, 2025
    Publication date: August 7, 2025
    Inventors: Darren H. WAKEFIELD, Lauren ALMEIDA, David ROZEMA, Omri GOTTESMAN, David LEWIS
  • Patent number: 12378556
    Abstract: Provided herein are oligonucleotide compositions that inhibit ANGPTL7 and reduce intraocular pressure when administered to an eye. The oligonucleotide compositions contain nucleoside modifications.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: August 5, 2025
    Assignee: EMPIRICO INC.
    Inventors: Omri Gottesman, Shannon Bruse, Paul Buske, Brian Cajes, David Lewis, David Rozema
  • Patent number: 12374148
    Abstract: A machine translation of a document is created via a compilation of services by mapping textual content from an image to create a plurality of mapped locations correspondent to at least one object from the image, populating each of the mapped locations with at least one character indicative of the object, each character sharing at least one similar attribute, adding to the image the populated mapped locations, and highlighting at least a portion of the textual content in accordance with the populated at least one character. A compilation of services is provided for identifying, extracting, and assessing electronic images by using a layered approach that reduces time and improves reviewing of medical records and other kinds of documentation.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: July 29, 2025
    Assignee: DIGITAL MEDICAL RECORDS, LLC
    Inventor: David Lewis
  • Publication number: 20250228883
    Abstract: Molecules for inhibiting arachidonate 15-lipoxygenase (ALOX-15) gene products including dsRNA (dsRNA) agents such as small interfering RNAs (siRNAs), antisense oligonucleotides, and small molecule inhibitors for therapeutic use. Additionally provided are methods to inhibit the expression of a target gene by administering these agents for the treatment of diseases involving ALOX-15 gene products.
    Type: Application
    Filed: August 29, 2024
    Publication date: July 17, 2025
    Inventors: Shannon BRUSE, Brian CAJES, Omri GOTTESMAN, David ROZEMA, David LEWIS
  • Publication number: 20250197859
    Abstract: Provided herein are compositions comprising an oligonucleotide that targets ANGPTL7. In some embodiments, the oligonucleotide includes modified nucleotides. In some embodiments, the oligonucleotide may be used to reduce intraocular pressure in a subject's eye.
    Type: Application
    Filed: March 27, 2023
    Publication date: June 19, 2025
    Inventors: Omri GOTTESMAN, Shannon BRUSE, Paul BUSKE, Brian CAJES, David LEWIS, David ROZEMA