Patents by Inventor David Limburg

David Limburg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzopyran compounds useful for treating inflammatory conditions
    Patent number: 7259266
    Abstract: The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: August 21, 2007
    Assignee: Pharmacia Corporation
    Inventors: Jeffry Carter, David Brown, Li Xing, Karl Aston, John Springer, Francis Koszyk, Steven Kramer, Renee Huff, Yi Yu, Bruce Hamper, Subo Laio, Angela Deprow, Teresa Fletcher, E. Ann Hallinan, James Kiefer, David Limburg, Lijuan Wang, Cindy Ludwig, John McCall, John Talley
  • Benzopyran compounds useful for treating inflammatory conditions
    Publication number: 20050148777
    Abstract: The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R 2, R3, and R4 are as described in the specification.
    Type: Application
    Filed: March 16, 2004
    Publication date: July 7, 2005
    Inventors: Jeffery Carter, David Brown, Li Xing, Karl Aston, John Springer, Francis Koszyk, Steven Kramer, Renee Huff, Yi Yu, Bruce Hamper, Subo Laio, Angela Deprow, Theresa Fletcher, E. Hallinan, James Kiefer, David Limburg, Lijuan Wang, Cindy Ludwig, John McCall, John Talley
  • Benzopyran compounds for use in the treatment and prevention of inflammation related conditions
    Publication number: 20050148627
    Abstract: The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.
    Type: Application
    Filed: March 16, 2004
    Publication date: July 7, 2005
    Inventors: Jeffery Carter, David Brown, Li Xing, Karl Aston, John Springer, Francis Koszyk, Steven Kramer, Sofya Tsymbalov, Renee Huff, Yi Yu, Bruce Hamper, Subo Laio, Angela Deprow, Theresa Fletcher, E. Hallinan, James Kiefer, David Limburg, Lijuan Wang
  • Trisubstituted carbocyclic cyclophilin binding compounds and their use
    Publication number: 20040157919
    Abstract: The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one or more of the said compounds. The invention further relates to the uses of these compounds and compositions for binding CyP-type proteins, inhibiting their peptidyl-prolyl isomerase activity, and for research, development, and therapeutic applications in a variety of medical disorders.
    Type: Application
    Filed: November 14, 2003
    Publication date: August 12, 2004
    Inventors: Yong-Qian Wu, Sergei Belyakov, Gregory S. Hamilton, David Limburg, Joseph P. Steiner, Mark Vaal, Ling Wei, Douglas Wilkinson
  • Trisubstituted carbocyclic cyclophilin binding compounds and their use
    Patent number: 6656971
    Abstract: The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one or more of the said compounds. The invention further relates to the uses of these compounds and compositions for binding CyP-type proteins, inhibiting their peptidyl-prolyl isomerase activity, and for research, development, and therapeutic applications in a variety of medical disorders.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: December 2, 2003
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Yong-Qian Wu, Sergei Belyakov, Gregory S. Hamilton, David Limburg, Joseph P. Steiner, Mark Vaal, Ling Wei, Douglas Wilkinson
  • Trisubstituted carbocyclic cyclophilin binding compounds and their use
    Publication number: 20020165275
    Abstract: The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one or more of the said compounds. The invention further relates to the uses of these compounds and compositions for binding CyP-type proteins, inhibiting their peptidyl-prolyl isomerase activity, and for research, development, and therapeutic applications in a variety of medical disorders.
    Type: Application
    Filed: January 25, 2002
    Publication date: November 7, 2002
    Inventors: Yong-Qian Wu, Sergei Belyakov, Gregory S. Hamilton, David Limburg, Joseph P. Steiner, Mark Vaal, Ling Wei, Douglas Wilkinson