Patents by Inventor David Lips

David Lips has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250283057
    Abstract: Provided are a method for producing a novel plasmid in heterologous expression of a gene and a plasmid. The method includes preparing a first gene cluster containing the plurality of genes by a DNA assembly method using a plasmid transformation system of Bacillus subtilis; and linking, to the first gene cluster, a second gene cluster containing a replication origin of Bacillus subtilis, a replication origin of Escherichia coli, and an initiation sequence for conjugation to an actinomycete.
    Type: Application
    Filed: May 24, 2022
    Publication date: September 11, 2025
    Applicant: Spiber Inc.
    Inventors: David Lips, Gijs Verkleij
  • Publication number: 20230174997
    Abstract: The present invention relates to a method for preparing a plasmid containing DNA that encodes a Type I polyketide synthase (PKS), the method including a step of introducing a DNA construct containing tandem repeats of DNA that encodes a PKS into a Bacillus subtilis competent cell.
    Type: Application
    Filed: May 25, 2021
    Publication date: June 8, 2023
    Applicant: Spiber Inc.
    Inventors: David Lips, Gijs Verkleij
  • Publication number: 20230174956
    Abstract: The present invention relates to a method of preparing a gene cluster construct including a plurality of genes encoding a multi-modular biosynthetic enzyme, the method including (A) a step of preparing a plurality of DNA fragments which are capable of reconstructing the gene cluster construct and have structures that can be ligated to each other and (B) a step of ligating the plurality of DNA fragments prepared in the step (A) to each other by mixing the plurality of DNA fragments in a solution to obtain the gene cluster construct.
    Type: Application
    Filed: May 25, 2021
    Publication date: June 8, 2023
    Applicant: Spiber Inc.
    Inventors: David Lips, Gijs Verkleij