Patents by Inventor David Lockwood Manning

David Lockwood Manning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for predicting the behaviour of breast tumours
    Patent number: 5693465
    Abstract: The estrogen-regulated gene sequence pLIV1 has been discovered and isolated, and found to be significantly associated with the metastatic spread of breast cancer cells to the regional lymph nodes. Methods are therefore provided for determining the risk of metastasis of a female breast tumour, as well as for predicting the responsiveness to endocrine treatment of a female breast tumour, which involve determining whether a tissue sample from a tumour expresses a polypeptide containing the pLIV1 gene sequence, or a substantial portion thereof.
    Type: Grant
    Filed: September 22, 1994
    Date of Patent: December 2, 1997
    Assignee: University of Wales College of Medicine
    Inventors: David Lockwood Manning, Robert Ian Nicholson, Julia Margaret Wendy Gee, Christopher Douglas Green