Patents by Inventor David Loebenberg

David Loebenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5776912
    Abstract: An aqueous pharmaceutical composition comprising a lipophilic oligosaccharide antibiotic salt, e.g., the N-methylglucamine salt of the everninomicin-type antibiotic of Formula III together with a binding agent such as human serum albumin or recombinant human albumin and a tonicity agent such as mannitol, is disclosed.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: July 7, 1998
    Assignee: Schering Corporation
    Inventors: Mahesh G. Patel, Vincent P. Gullo, Roberta S. Hare, David Loebenberg, Heewon Y. Kwon, George H. Miller
  • Patent number: 5624914
    Abstract: Pharmaceutically acceptable compositions of matter comprising a lipophilic oligosaccharide antibiotic, e.g., the everninomicin-type antibiotic of Formula III, at least a stoichiometric amount of a base, e.g., N-methylglucamine, an amount of, e.g., hydroxypropyl-.beta.-cyclodextrin, and optionally a pharmaceutically acceptable non-ionic surfactant, e.g., Tween-80, pharmaceutical compositions containing such compositions of matter, methods of treating and preventing susceptible bacterial infections in animals especially human beings as well as a method of preventing adverse reaction syndrome while simultaneously delivering an antiinfective amount of a lipophilic oligosaccharide antibiotic such as that of Formula III to said animals as well as the use of the compositions of matter for the preparation of a medicament for such treating or preventing are disclosed.
    Type: Grant
    Filed: April 12, 1994
    Date of Patent: April 29, 1997
    Assignee: Schering Corporation
    Inventors: Mahesh Patel, Vincent P. Gullo, Roberta Hare, David Loebenberg, James B. Morton, George H. Miller, Heewon Y. Kwon
  • Patent number: 4299845
    Abstract: The present invention relates to topical compositions and methods of use utilizing compounds of the formula ##STR1## wherein X is oxygen or sulfur;W is a bridge group of the formulae ##STR2## wherein R is hydrogen alkyl of 1 to 7 carbon atoms, cycloalkyl of 4-8 carbon atoms, cycloalkenyl of 5-8 carbon atoms, polyfluoroalkyl of 1-4 carbon atoms, phenyl, benzyl or alkoxycarbonylmethyl; R.sub.1 is hydrogen or alkyl of 1-7 carbon atoms; m is 0-2; n is 1-4; with the proviso that m+n is 3-5; andA.sub.1, A.sub.2, A.sub.3, A.sub.4, B.sub.1, B.sub.2, B.sub.3, and B.sub.4 are independently selected from the group consisting of hydrogen, methyl, cyano, nitro, polyfluoroalkyl of 1-3 carbon atoms, chloro, bromo, fluoro and alkylthio, with the proviso that 2-5 of there are hydrogen of which at least one of A.sub.1, A.sub.2, A.sub.3 and A.sub.4 and at least one of B.sub.1, B.sub.2, B.sub.3 and B.sub.4 is hydrogen.
    Type: Grant
    Filed: April 14, 1980
    Date of Patent: November 10, 1981
    Assignee: Schering Corporation
    Inventors: David Loebenberg, Elijah H. Gold