Patents by Inventor David Lonergan

David Lonergan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetracyclic autotaxin inhibitors
    Patent number: 9926318
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: March 27, 2018
    Assignee: PHARMAKEA, INC.
    Inventors: John Howard Hutchinson, David Lonergan, Martin Rowbottom, Andiliy Gokching Lai
  • LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF
    Publication number: 20180057458
    Abstract: Described herein are compounds that are LOXL2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with LOXL2 activity.
    Type: Application
    Filed: March 3, 2016
    Publication date: March 1, 2018
    Inventors: Martin W. ROWBOTTOM, John Howard HUTCHINSON, David LONERGAN
  • Autotaxin inhibitor compounds
    Patent number: 9850203
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: December 26, 2017
    Assignee: PHARMAKEA, INC.
    Inventors: John Howard Hutchinson, David Lonergan, Fei Huang, Martin Rowbottom, Imelda Calderon
  • Vinyl autotaxin inhibitor compounds
    Patent number: 9714240
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: July 25, 2017
    Assignee: PHARMAKEA, INC.
    Inventors: John Howard Hutchinson, Timothy Andrew Parr, David Lonergan
  • COMPOSITIONS AND METHODS OF DELIVERY OF DEUBIQUITINASE INHIBITORS
    Publication number: 20170095457
    Abstract: Described herein are compositions comprising deubiquitinase inhibitors in combination with albumin, methods of making such compositions, and methods of using such compositions in the treatment of conditions, diseases, or disorders that would benefit from inhibition of deubiquitinase activity.
    Type: Application
    Filed: May 27, 2015
    Publication date: April 6, 2017
    Inventors: David LONERGAN, John Howard HUTCHINSON
  • DEUBIQUITINASE INHIBITORS
    Publication number: 20170088520
    Abstract: Described herein are compounds that are deubiquitinase inhibitors, methods of making pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from inhibition of deubiquitinase activity.
    Type: Application
    Filed: May 27, 2015
    Publication date: March 30, 2017
    Inventors: Andiliy LAI, John Howard HUTCHINSON, David LONERGAN, Fei HUANG
  • AUTOTAXIN INHIBITOR COMPOUNDS
    Publication number: 20160374991
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Application
    Filed: September 9, 2016
    Publication date: December 29, 2016
    Inventors: John Howard HUTCHINSON, David LONERGAN
  • Autotaxin inhibitor compounds
    Patent number: 9468628
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: October 18, 2016
    Assignee: PHARMAKEA, INC
    Inventors: John Howard Hutchinson, David Lonergan
  • TETRACYCLIC AUTOTAXIN INHIBITORS
    Publication number: 20160264575
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Application
    Filed: November 20, 2014
    Publication date: September 15, 2016
    Inventors: John Howard HUTCHINSON, David LONERGAN, Martin ROWBOTTOM, Andiliy Gokching LAI
  • AUTOTAXIN INHIBITOR COMPOUNDS
    Publication number: 20160235713
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Application
    Filed: March 3, 2016
    Publication date: August 18, 2016
    Inventors: John Howard HUTCHINSON, David LONERGAN
  • HETEROCYCLIC VINYL AUTOTAXIN INHIBITOR COMPOUNDS
    Publication number: 20160229809
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Application
    Filed: September 16, 2014
    Publication date: August 11, 2016
    Inventors: John Howard HUTCHINSON, Timothy Andrew PARR, Kevin Duane BUNKER, David LONERGAN
  • VINYL AUTOTAXIN INHIBITOR COMPOUNDS
    Publication number: 20160222000
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Application
    Filed: September 16, 2014
    Publication date: August 4, 2016
    Inventors: John Howard HUTCHINSON, Timothy Andrew PARR, David LONERGAN
  • AUTOTAXIN INHIBITOR COMPOUNDS
    Publication number: 20160214935
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Application
    Filed: September 25, 2014
    Publication date: July 28, 2016
    Inventors: John Howard HUTCHINSON, David LONERGAN, Fei HUANG, Martin ROWBOTTOM, Imelda CALDERON
  • Autotaxin inhibitor compounds
    Patent number: 9334261
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: May 10, 2016
    Assignee: PHARMAKEA, INC.
    Inventors: John Howard Hutchinson, David Lonergan
  • AUTOTAXIN INHIBITOR COMPOUNDS
    Publication number: 20160046614
    Abstract: Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.
    Type: Application
    Filed: October 29, 2015
    Publication date: February 18, 2016
    Inventors: John Howard HUTCHINSON, David LONERGAN
  • NOVEL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF
    Publication number: 20100022531
    Abstract: Compounds are disclosed that have a formula represented by the following (1), the compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: September 1, 2006
    Publication date: January 28, 2010
    Applicant: RENOVIS, INC.
    Inventors: John Kincaid, Yeyu Cao, Carl Kaub, David Lonergan, Michael G. Kelly
  • Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
    Patent number: 7414131
    Abstract: Amine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: August 19, 2008
    Assignee: Renovis, Inc.
    Inventors: Michael G. Kelly, Satyanarayana Janagani, Guoxian Wu, John Kincaid, David Lonergan, YunFeng Fang, Zhi-Liang Wei
  • Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
    Patent number: 7312330
    Abstract: Amine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: December 25, 2007
    Assignee: Renovis, Inc.
    Inventors: Michael G. Kelly, Satyanarayana Janagani, Guoxian Wu, John Kincaid, David Lonergan, YunFeng Fang, Zhi-Liang Wei
  • Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
    Publication number: 20050277643
    Abstract: Amine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: May 4, 2005
    Publication date: December 15, 2005
    Inventors: Michael Kelly, Satyanarayana Janagani, Guoxian Wu, John Kincaid, David Lonergan, YunFeng Fang, Zhi-Liang Wei
  • Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
    Publication number: 20050215572
    Abstract: Amine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
    Type: Application
    Filed: December 23, 2004
    Publication date: September 29, 2005
    Inventors: Michael Kelly, Satyanarayana Janagani, Guoxian Wu, John Kincaid, David Lonergan, YunFeng Fang, Zhi-Liang Wei