Abstract: A selective tissue conductance meter is described which can be used to assess pain, abnormal sensation or sympathetic dysfunction in a human being or animal. Two concentric electrodes are mounted in fixed relative relationship on a housing which is capable of being held in one hand of the user. Contained in the housing is an electric circuit connected to the two electrodes, which circuit produces an electrical signal having a pulse frequency that varies according to the measured conductance. A battery capable of providing low voltage power is connected to the circuit. Several devices are disclosed for monitoring or measuring the electrical signal to permit the user to detect the pulse frequency of the signal. One such device comprises an audio circuit capable of producing an audible sound or click for each pulse of the electrical signal. A liquid crystal display can provide a digital readout of the number of pulses covered over a short time span.