Patents by Inventor David Louis Shelton

David Louis Shelton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING OSTEOARTHRITIS PAIN BY ADMINISTERING A NERVE GROWTH FACTOR ANTAGONIST AND COMPOSITIONS CONTAINING THE SAME
    Publication number: 20130302325
    Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
    Type: Application
    Filed: July 19, 2013
    Publication date: November 14, 2013
    Inventors: ARNON ROSENTHAL, DAVID LOUIS SHELTON, PATRICIA ANN WALICKE
  • METHODS OF TREATING CHRONIC PAIN
    Publication number: 20130295087
    Abstract: The invention relates to an anti-CGRP antibody for use in the prevention and/or treatment of chronic pain and/or symptoms of chronic pain, and to a method of treating and/or preventing chronic pain and/or symptoms of chronic pain using an anti-CGRP antibody.
    Type: Application
    Filed: May 10, 2013
    Publication date: November 7, 2013
    Inventors: Kristian Todd Poulsen, David Louis Shelton, Joerg Zeller, Ian Machin, Laura Corradini
  • METHODS OF TREATING INFLAMMATORY PAIN
    Publication number: 20130295088
    Abstract: The invention relates to an anti-CGRP antibody for use in the prevention and/or treatment of inflammatory pain and/or symptoms of inflammatory pain, and to a method of treating and/or preventing inflammatory pain and/or symptoms of inflammatory pain using an anti-CGRP antibody.
    Type: Application
    Filed: May 10, 2013
    Publication date: November 7, 2013
    Inventors: Kristian Todd Poulsen, David Louis Shelton, Joerg Zeller, Ian Machin, Laura Corradini
  • Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
    Patent number: 8540990
    Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
    Type: Grant
    Filed: April 11, 2006
    Date of Patent: September 24, 2013
    Assignee: Rinat Neuroscience Corp.
    Inventors: Arnon Rosenthal, David Louis Shelton, Patricia Ann Walicke
  • Treatment of chronic prostatitis
    Patent number: 8481036
    Abstract: The present invention relates to the use of an anti-NGF antibody in the treatment or prevention of pain and/or a lower urinary tract symptom (LUTS) associated with chronic prostatitis and/or chronic pelvic pain syndrome.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: July 9, 2013
    Assignee: Pfizer Inc.
    Inventor: David Louis Shelton
  • Methods of treating inflammatory pain
    Patent number: 8298536
    Abstract: Methods of Treating Inflammatory Pain The invention relates to an anti-CGRP antibody for use in the prevention and/or treatment of inflammatory pain and/or symptoms of inflammatory pain, and to a method of treating and/or preventing inflammatory pain and/or symptoms of inflammatory pain using an anti-CGRP antibody.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: October 30, 2012
    Assignee: Pfizer Limited
    Inventors: Laura Corradini, Ian Machin, Kristian Todd Poulsen, David Louis Shelton, Joerg Zeller
  • Methods of treating chronic pain
    Patent number: 8293239
    Abstract: The invention relates to an anti-CGRP antibody for use in the prevention and/or treatment of chronic pain and/or symptoms of chronic pain, and to a method of treating and/or preventing chronic pain and/or symptoms of chronic pain using an anti-CGRP antibody.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: October 23, 2012
    Assignee: Pfizer Limited
    Inventors: Kristian Todd Poulsen, David Louis Shelton, Joerg Zeller, Ian Machin, Laura Corradini
  • METHODS FOR TREATING VISCERAL PAIN BY ADMINISTERING ANTAGONIST ANTIBODIES DIRECTED AGAINST CALCITONIN GENE-RELATED PEPTIDE
    Publication number: 20120225075
    Abstract: The invention features methods for preventing or treating visceral pain, including pain associated with functional bowel disorder, inflammatory bowel disease and interstitial cystitis, by administering an anti-CGRP antagonist antibody.
    Type: Application
    Filed: August 23, 2010
    Publication date: September 6, 2012
    Inventors: Ariel Ates Pios, Kristian Todd Poulsen, David Louis Shelton, Joerg Zeller
  • Methods of Treating Chronic Pain
    Publication number: 20110257371
    Abstract: Methods of Treating Chronic Pain The invention relates to an anti-CGRP antibody for use in the prevention and/or treatment of chronic pain and/or symptoms of chronic pain, and to a method of treating and/or preventing chronic pain and/or symptoms of chronic pain using an anti-CGRP antibody.
    Type: Application
    Filed: March 3, 2009
    Publication date: October 20, 2011
    Inventors: Kristian Todd Poulsen, David Louis Shelton, Joerg Zeller, Ian Machin, Laura Corradini
  • Antibodies with pH Dependent Antigen Binding
    Publication number: 20110229489
    Abstract: The present invention relates to antibodies with pH dependent binding to its antigen such that the affinity for antigen binding at physiological pH (i.e., pH 7.4) is greater than at endosomal pH (i.e., pH 6.0 or 5.5). In other words, the KD or koff ratio at pH 5.5/pH 7.4 or at pH 6.0/pH 7.4 is more than, or ranges between, 2, 3, 4, 8, 10, 16, 20, 30, 40, or 100 or more. Such pH dependent antibodies preferentially dissociate from the antigen in the endosome. This can increase antibody half life, as compared to antibodies with equivalent KDs at pH 7.4 but with no pH dependent binding, when the antigen is one that undergoes antigen-mediated clearance (e.g., PCSK9). Antibodies with pH dependent binding can decrease total antigen half life when the antigen undergoes reduced clearance when bound to antibody (e.g., IL6). Antibodies with pH dependent binding can also prolong the decrease in antigen which is not antibody-bound.
    Type: Application
    Filed: March 10, 2011
    Publication date: September 22, 2011
    Inventors: Jaume Pons, Jeffrey Raymond Chabot, Javier Fernando Chaparro Riggers, Bruce Charles Gomes, Hong Liang, Kapil Mayawala, Jerome Thomas Mettetal, II, Arvind Rajpal, David Louis Shelton
  • Treatment of Chronic Prostatitis
    Publication number: 20110097341
    Abstract: The present invention relates to the use of an anti-NGF antibody in the treatment or prevention of pain and/or a lower urinary tract symptom (LUTS) associated with chronic prostatitis and/or chronic pelvic pain syndrome.
    Type: Application
    Filed: June 15, 2009
    Publication date: April 28, 2011
    Inventor: David Louis Shelton
  • Methods of Treating Inflammatory Pain
    Publication number: 20110054150
    Abstract: Methods of Treating Inflammatory Pain The invention relates to an anti-CGRP antibody for use in the prevention and/or treatment of inflammatory pain and/or symptoms of inflammatory pain, and to a method of treating and/or preventing inflammatory pain and/or symptoms of inflammatory pain using an anti-CGRP antibody.
    Type: Application
    Filed: March 3, 2009
    Publication date: March 3, 2011
    Inventors: Kristian Todd Poulsen, David Louis Shelton, Joerg Zeller, Ian Machin, Laura Corradini
  • Methods for Treating Osteoarthritis Pain By Administering a Nerve Growth Factor Antagonist and Compositions Containing the Same
    Publication number: 20110033447
    Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
    Type: Application
    Filed: May 23, 2006
    Publication date: February 10, 2011
    Inventors: Arnon Rosenthal, David Louis Shelton, Patricia Ann Walicke
  • Treatment Of Interstitial Cystitis
    Publication number: 20100260775
    Abstract: The present invention relates to the use of an anti-NGF antibody in the treatment or prevention of pain and/or a lower urinary tract symptom (LUTS) associated with interstitial cystitis and/or painful bladder syndrome and/or bladder pain syndrome.
    Type: Application
    Filed: December 17, 2008
    Publication date: October 14, 2010
    Inventors: Ian William Mills, Stephen Charles Phillips, Arnon Rosenthal, David Peter Scholfield, David Louis Shelton