Patents by Inventor David Lui

David Lui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11426371
    Abstract: The present application provides novel compositions and methods for treating acute myeloid leukemia (AML). Compounds of the invention are acid ceramidase inhibitors, reduce AML cell viability, inhibit AML cell proliferation, increase cell death of AML cells, and induce apoptosis in AML cells. A primary compound of the invention is SACLAC: 2-chloro-N-((2S,3R)-1,3-dihydroxyoctadecan-2-yl)acetamide. The bromine analog of SACLAC (SABRAC: 2-bromo-N-((2S,3R)-1,3-dihydroxyoctadecan-2-yl)acetamide) is also useful for treating AML. SACLAC has much better activity than other know drugs used to treat AML.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: August 30, 2022
    Assignees: University of Virginia Patent Foundation, Universität de Barcelona, Consejo Superior de Investigaciones Cientificas (CSIC)
    Inventors: Thomas P. Loughran, Jr., Gemma Fabrias, Jose Luis Abad, Josefina Casas, David J. Feith, Su-Fern Tan, Jennifer M. Pearson, Antonio Delgado Cirilo
  • Publication number: 20220270331
    Abstract: Presenting a virtual object includes obtaining, by a first device, a first geometric representation and a second geometric representation corresponding to a physical surface in a real environment, determining an initialization location on the first physical surface for a virtual object, obtaining a first normal for the first representation and a second normal for the second representation at the initialization location, and rendering the virtual object at the initialization location based on the first normal and the second normal.
    Type: Application
    Filed: May 11, 2022
    Publication date: August 25, 2022
    Inventors: David Lui, Hon-ming Chen, Shuai Song, Xiao Jin Yu
  • Publication number: 20220247177
    Abstract: The present disclosure provides a photovoltaic solar inverter with an AC grid filter without inductance connectable to the AC grid. The inverter comprises: a power module for converting a DC input voltage into a three-phase AC output voltage; a three-phase AC/AC transformer for adapting the three-phase AC output voltage of the power module to the three-phase AC voltage of the AC grid, which has an inductance “L2”. The three-phase AC/AC transformer comprises a winding on the grid side with an equivalent inductance “L1”; a capacitor “C”, connected to the winding of the grid side of the three-phase AC/AC transformer. The equivalent inductance “L1” of the AC/AC transformer, the capacitor “C” and the inductance “L2” of the AC grid form a high frequency “LCL” filter, eliminating the inductances provided only for forming the LCL filter. The disclosure also provides an AC grid filter without inductance with an “LLCL” typology.
    Type: Application
    Filed: January 26, 2022
    Publication date: August 4, 2022
    Inventors: David Salvo Lillo, Abelardo Salvo Lillo, Josué Juan Aguilar, José Luis Camps Soriano, Eusebio Rodrigo Mañez
  • Publication number: 20220229067
    Abstract: Compositions and methods are provided for the identification of peptide sequences that are ligands for a T cell receptor (TCR) of interest, in a given MHC context.
    Type: Application
    Filed: July 16, 2021
    Publication date: July 21, 2022
    Inventors: MICHAEL EDWARD BIRNBAUM, JUAN LUIS MENDOZA, MICHAEL THOMAS BETHUNE, DAVID BALTIMORE, KENAN CHRISTOPHER GARCIA
  • Patent number: 11393164
    Abstract: In one embodiment, a method of generating a 3D object is performed by a device including a processor, non-transitory memory, and one or more input devices. The method includes receiving, via one or more input devices, a user input selecting a file representing two-dimensional (2D) content and having a file type. The method includes receiving, via the one or more input devices, a user input requesting generation of a three-dimensional (3D) object based on the file. The method includes generating, based on the file type, a 3D object representing the 2D content.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: July 19, 2022
    Assignee: APPLE INC.
    Inventors: Tyler Casella, David Lui, Xiao Jin Yu, Kyle Ellington Fisher
  • Patent number: 11384736
    Abstract: A floating offshore wind turbine includes a rotor and a generator turned by the rotor. An elongated buoyant body supports a tower that supports the generator and rotor. The buoyant body or the tower may support aerodynamic features to counteract heeling forces or to steer the floating wind turbine as it swings on its anchor line. The floating offshore wind turbine may be configured to move the anchor line force vector to counteract heeling forces. A control system may control the aerodynamic features and the movement of the anchor line force vector.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: July 12, 2022
    Inventors: Frederick W. Piasecki, Dinesh Barwey, George Luis Firpi, David Joseph Stilwell
  • Publication number: 20220207437
    Abstract: Method and device The invention relates to a method for improving the efficiency of a vehicle fleet, in particular a vehicle fleet used for public transport, with: a) Determining driving circumstances for vehicles (16) within the vehicle fleet (14); b) Gathering operating parameters relating to an operation of the vehicle fleet (14), including gathering operating parameters for a plurality of vehicles (16) having comparable driving circumstances; c) Determining the service efficiency for at least those vehicles (16) of the vehicle fleet (14) having comparable driving circumstances; d) Determining at least one preferred set of operating parameters for the vehicles (16) having comparable driving circumstances by means of which a desired level of the service efficiency can be reached; e) Determining by way of a computer reasoning system at least one measure for achieving the desired value of the service efficiency parameter, said measure being implementable with respect to at least some of the comparable driving
    Type: Application
    Filed: May 19, 2019
    Publication date: June 30, 2022
    Inventors: Fernando Aparicio Martínez, Abel Rionda Rodríguez, David Martínez Álvarez, Alberto Álvarez González, David Arbesú Carbajal, Sonia Menéndez Rodríguez, Adrián García Allende, José Luis Bango Bustelo, Xabiel García Pañeda, Roberto García Fernández, David Melendi Palacio, Laura Pozueco Álvarez, Victor Corcoba Mañaga, Alejandro García Tuero
  • Patent number: 11354869
    Abstract: Presenting a virtual object includes obtaining, by a first device, a first geometric representation and a second geometric representation corresponding to a physical surface in a real environment, determining an initialization location on the first physical surface for a virtual object, obtaining a first normal for the first representation and a second normal for the second representation at the initialization location, and rendering the virtual object at the initialization location based on the first normal and the second normal.
    Type: Grant
    Filed: March 17, 2021
    Date of Patent: June 7, 2022
    Assignee: Apple Inc.
    Inventors: David Lui, Hon-ming Chen, Shuai Song, Xiao Jin Yu
  • Publication number: 20220130089
    Abstract: According to various embodiments, a method of presenting a computer-generated reality (CGR) file includes receiving user inputs to present a CGR scene including one or more CGR objects. The CGR scene is associated with an anchor. The anchor is selected via a user input directed to an anchor selection affordance of a user interface. The method further includes capturing an image of a physical environment, and determining that a portion of the image corresponds to the anchor. Based on determining that the portion of the image corresponds to the anchor, the method includes displaying the CGR scene at a location of the display corresponding to the portion of the image corresponding to the anchor.
    Type: Application
    Filed: January 5, 2022
    Publication date: April 28, 2022
    Inventors: Tyler Casella, David Lui, Norman Nuo Wang, Xiao Jin Yu
  • Publication number: 20220058882
    Abstract: An electronic device displays a first user interface with a first representation of content and, in response to receiving a request to display a virtual model that corresponds to the content, displays the virtual model of the content concurrently with a selectable user interface object for performing the operation associated with the content in accordance with a determination that the first user interface is configured to perform an operation associated with the content and displaying the virtual model of the content without displaying the selectable user interface object for performing the operation associated with the content in accordance with a determination that the first user interface is not configured to perform the operation associated with the content.
    Type: Application
    Filed: October 1, 2021
    Publication date: February 24, 2022
    Inventors: Grant R. Paul, Giancarlo Yerkes, Nicolas V. Scapel, David Lui
  • Patent number: 11250604
    Abstract: In one embodiment, a method of presenting a computer-generated reality (CGR) file includes receiving a user input to present a CGR scene including one or more CGR objects, wherein the CGR scene is associated with a first anchor and a second anchor. The method includes capturing an image of a physical environment and determining that the image of the physical environment lacks a portion corresponding to the first anchor. The method includes detecting a portion of the image of the physical environment corresponding to the second anchor. The method includes, in response to determining that image of the physical environment lacks a portion corresponding to the first anchor and detecting a portion of the image of the physical environment corresponding to the second anchor, displaying the CGR scene at a location of the display corresponding to the second anchor.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: February 15, 2022
    Assignee: APPLE INC.
    Inventors: Tyler Casella, David Lui, Norman Nuo Wang, Xiao Jin Yu
  • Patent number: 11138798
    Abstract: An electronic device displays an environment that includes a virtual object that is associated with a first action that is triggered based on satisfaction of a first set of criteria. In response to a first input detected while the environment is displayed: the first action is performed in accordance with a determination that the first input satisfies the first set of criteria, and, in accordance with a determination that the first input does not satisfy the first set of criteria but instead satisfies a second set of criteria, the first action is not performed and instead a first visual indication of one or more inputs that if performed would cause the first set of criteria to be satisfied is displayed.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: October 5, 2021
    Assignee: APPLE INC.
    Inventors: Grant R. Paul, David Lui, Mathew A. Mason
  • Publication number: 20210295603
    Abstract: Presenting a virtual object includes obtaining, by a first device, a first geometric representation and a second geometric representation corresponding to a physical surface in a real environment, determining an initialization location on the first physical surface for a virtual object, obtaining a first normal for the first representation and a second normal for the second representation at the initialization location, and rendering the virtual object at the initialization location based on the first normal and the second normal.
    Type: Application
    Filed: March 17, 2021
    Publication date: September 23, 2021
    Inventors: David Lui, Hon-ming Chen, Shuai Song, Xiao Jin Yu
  • Patent number: 11099707
    Abstract: A computer system with a display, a touch-sensitive surface, and one or more cameras displays a virtual object in a first user interface region. In response to detecting a first input at a location that corresponds to the virtual object and in accordance with a determination that the first input meets first criteria, the virtual object is displayed in a second user interface region. In response to detecting a second input, in accordance with a determination that the second input corresponds to a request to manipulate the virtual object in the second user interface region, a display property of the virtual object is changed, and in accordance with a determination that the second input corresponds to a request to display the virtual object in an augmented reality environment, the virtual object is displayed with a representation of a field of view of the one or more cameras.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: August 24, 2021
    Assignee: APPLE INC.
    Inventors: Philipp Rockel, Jonathan R. Dascola, Stephen O. Lemay, Jeffrey M. Faulkner, David J. Addey, David Lui, Giancarlo Yerkes
  • Patent number: 11017608
    Abstract: An electronic device, while displaying a first user interface region and a first media item, detects a first input corresponding to a sharing user interface. In response, the device displays the sharing user interface, which includes a second user interface object for initiating a process for displaying a second representation of a first media item in an augmented reality environment. In response to detecting a sequence of one or more inputs including selection of the second user interface object, the device displays the second representation of the first media item in a second user interface that includes content of at least a portion of a field of view of the device's one or more cameras.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: May 25, 2021
    Assignee: APPLE INC.
    Inventors: Grant R. Paul, Nicolas V. Scapel, David Lui, Xiao Jin Yu, Giancarlo Yerkes, Kyle E. Fisher
  • Patent number: 10984607
    Abstract: One exemplary implementation involves performing operations at a device with one or more processors, a camera, and a computer-readable storage medium, such as a desktop computer, laptop computer, tablet, or mobile phone. The device receives a data object corresponding to three dimensional (3D) content from a separate device. The device receives input corresponding to a user selection to view the 3D content in a computer generated reality (CGR) environment, and in response, displays the CGR environment at the device. To display the CGR environment the device uses the camera to capture images and constructs the CGR environment using the data object and the captured images.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: April 20, 2021
    Assignee: Apple Inc.
    Inventors: Norman N. Wang, Wei Lun Huang, David Lui, Tyler L. Casella, Ross R. Dexter
  • Publication number: 20200356240
    Abstract: An electronic device displays an environment that includes a virtual object that is associated with a first action that is triggered based on satisfaction of a first set of criteria. In response to a first input detected while the environment is displayed: the first action is performed in accordance with a determination that the first input satisfies the first set of criteria, and, in accordance with a determination that the first input does not satisfy the first set of criteria but instead satisfies a second set of criteria, the first action is not performed and instead a first visual indication of one or more inputs that if performed would cause the first set of criteria to be satisfied is displayed.
    Type: Application
    Filed: September 24, 2019
    Publication date: November 12, 2020
    Inventors: Grant R. Paul, David Lui, Mathew A. Mason
  • Publication number: 20200357169
    Abstract: In one embodiment, a method of generating a 3D object is performed by a device including a processor, non-transitory memory, and one or more input devices. The method includes receiving, via one or more input devices, a user input selecting a file representing two-dimensional (2D) content and having a file type. The method includes receiving, via the one or more input devices, a user input requesting generation of a three-dimensional (3D) object based on the file. The method includes generating, based on the file type, a 3D object representing the 2D content.
    Type: Application
    Filed: May 6, 2019
    Publication date: November 12, 2020
    Inventors: Tyler Casella, David Lui, Xiao Jin Yu, Kyle Ellington Fisher
  • Publication number: 20200357184
    Abstract: An electronic device, while displaying a first user interface region and a first media item, detects a first input corresponding to a sharing user interface. In response, the device displays the sharing user interface, which includes a second user interface object for initiating a process for displaying a second representation of a first media item in an augmented reality environment. In response to detecting a sequence of one or more inputs including selection of the second user interface object, the device displays the second representation of the first media item in a second user interface that includes content of at least a portion of a field of view of the device's one or more cameras.
    Type: Application
    Filed: July 14, 2020
    Publication date: November 12, 2020
    Inventors: Grant R. Paul, Nicolas V. Scapel, David Lui, Xiao Jin Yu, Giancarlo Yerkes, Kyle E. Fisher
  • Publication number: 20200357155
    Abstract: In one embodiment, a method of presenting a computer-generated reality (CGR) file includes receiving a user input to present a CGR scene including one or more CGR objects, wherein the CGR scene is associated with a first anchor and a second anchor. The method includes capturing an image of a physical environment and determining that the image of the physical environment lacks a portion corresponding to the first anchor. The method includes detecting a portion of the image of the physical environment corresponding to the second anchor. The method includes, in response to determining that image of the physical environment lacks a portion corresponding to the first anchor and detecting a portion of the image of the physical environment corresponding to the second anchor, displaying the CGR scene at a location of the display corresponding to the second anchor.
    Type: Application
    Filed: June 3, 2020
    Publication date: November 12, 2020
    Inventors: Tyler Casella, David Lui, Norman Nuo Wang, Xiao Jin Yu