Abstract: A spinning electrode for production of polymeric nanofibres by electric or electrostatic spinning of a polymer solution or melt includes a conduit for the polymer solution or melt. A spinning surface on the conduit is defined by a face of the conduit or an extension on the conduit. A screw shaft is disposed within an inner space of the conduit, wherein the screw shaft and an inner wall of the conduit form a screw conveyor. The screw shaft has a lower end that projects out from the conduit and is connected to a hub of a magnetic coupling.

Abstract: The present disclosure encompasses solid state forms of Ixazomib Citrate and pharmaceutical compositions thereof. Also disclosed are processes for preparation of Ixazomib Citrate.

Abstract: A spinning electrode for production of polymeric nanofibres by electric or electrostatic spinning of a polymer solution or melt includes a conduit for the polymer solution or melt. A spinning surface on the conduit is defined by a face of the conduit or an extension on the conduit. A screw shaft is disposed within an inner space of the conduit, wherein the screw shaft and an inner wall of the conduit form a screw conveyor. The screw shaft has a lower end that projects out from the conduit and is connected to a hub of a magnetic coupling.

Abstract: The present disclosure encompasses solid state forms of Ixazomib Citrate and pharmaceutical compositions thereof. Also disclosed are processes for preparation of Ixazomib Citrate.

Abstract: A method, system, and resulting linear fibrous formation are provided wherein a supporting linear formation defines a core that is transported through a spinning chamber. A coating of polymeric nanofibers enveloping the supporting linear formation in the spinning chamber. The coating of polymeric nanofibers comprises a flat stripe wound around the core into a helical form, the flat stripe created from a hollow electrically neutral nanofibrous plume generated in a spinning space above a spinning electrode during spinning by AC electric voltage in the spinning chamber.

Abstract: The invention relates to a spinning electrode (1) for producing polymeric nanofibers by electrospinning of a polymer solution or polymer melt, containing an inlet pipe (2) of the polymer solution or melt, which ends on its top face (3), whereby around at least a part of the mouth (20) on the top face of the inlet pipe (2) of the polymer solution or melt is formed a spinning surface (4) rounded downwards below the mouth (20), whereby the spinning surface (4) continues as a collecting surface (6) on the outer surface of the inlet pipe (2) of the polymer solution or melt. The invention also relates to a device for producing nanofibers by electrospinning of a polymer solution or melt, which is equipped with at least one spinning electrode (1) according to the invention. In addition, the invention relates to a method for producing nanofibers by electrospinning of a polymer solution or melt, which is based on using the spinning electrode according to the invention.

Abstract: The present disclosure encompasses solid state forms of Ixazomib Citrate and pharmaceutical compositions thereof. Also disclosed are processes for preparation of Ixazomib Citrate.

Abstract: The present disclosure encompasses solid state forms of Ixazomib Citrate and pharmaceutical compositions thereof. Also disclosed are processes for preparation of Ixazomib Citrate.

Abstract: The present disclosure encompasses solid state forms of Ixazomib Citrate and pharmaceutical compositions thereof. Also disclosed are processes for preparation of Ixazomib Citrate.

Abstract: The invention relates to a spinning electrode (1) for producing polymeric nanofibers by electrospinning of a polymer solution or polymer melt, containing an inlet pipe (2) of the polymer solution or melt, which ends on its top face (3), whereby around at least a part of the mouth (20) on the top face of the inlet pipe (2) of the polymer solution or melt is formed a spinning surface (4) rounded downwards below the mouth (20), whereby the spinning surface (4) continues as a collecting surface (6) on the outer surface of the inlet pipe (2) of the polymer solution or melt. The invention also relates to a device for producing nanofibers by electrospinning of a polymer solution or melt, which is equipped with at least one spinning electrode (1) according to the invention. In addition, the invention relates to a method for producing nanofibers by electrospinning of a polymer solution or melt, which is based on using the spinning electrode according to the invention.

Abstract: A method, system, and resulting linear fibrous formation are provided wherein a supporting linear formation defines a core that is transported through a spinning chamber. A coating of polymeric nanofibers enveloping the supporting linear formation in the spinning chamber. The coating of polymeric nanofibers comprises a flat stripe wound around the core into a helical form, the flat stripe created from a hollow electrically neutral nanofibrous plume generated in a spinning space above a spinning electrode during spinning by AC electric voltage in the spinning chamber.

Abstract: The invention relates to a method for production of polymeric nanofibers, in which polymeric nanofibers are created due to the action of force of an electric field on solution or melt of a polymer, which is located on the surface of a spinning electrode, whereby the electric field for electrostatic spinning is created alternately between the spinning electrode (1), to which is supplied alternating voltage, and ions (30, 31) of air and/or gas generated and/or supplied to proximity of the spinning electrode (1), whereby according to the phase of the alternating voltage on the spinning electrode (1) polymeric nanofibers with an electric charge of opposite polarity and/or with segments with an electric charge of opposite polarity are created, which after their creation cluster together under the influence of the electrostatic forces into linear formation in the form of a tow or a band, which moves freely in space in direction of gradient of the electric fields away from the spinning electrode (1).

Abstract: Disclosed are membranes formed from self-assembling block copolymers, for example, a diblock copolymer of the formula (I): wherein R1-R4, n, and m are as described herein, which find use in preparing nanoporous membranes. Embodiments of the membranes contain the block copolymer that self-assembles into a cylindrical morphology. Also disclosed is a method of preparing such membrane which involves hybrid casting a polymer solution containing the block copolymer to obtain a thin film, followed by evaporation of some of the solvent from the thin film, and coagulating the resulting this film in a bath containing a nonsolvent or poor solvent for the block copolymer.

Abstract: Disclosed are membranes formed from self-assembling diblock copolymers of the formula (I): wherein R1-R4, n, and m are as described herein, which find use in preparing porous membranes. Embodiments of the membranes contain the diblock copolymer that self-assembles into a cylindrical morphology. Also disclosed is a method of preparing such a membrane which involves hybrid casting a polymer solution containing the diblock copolymer to obtain a thin film, followed by evaporation of some of the solvent from the thin film, and coagulating the resulting this film in a bath containing a nonsolvent or poor solvent for the diblock copolymer.

Abstract: A fluidic probe comprising a plurality of oriented fibers with individual fibers having nano-pores in the fiber bodies, the oriented fibers being twisted together, wherein the twisted oriented fibers form micro-pores between the individual fibers, is disclosed. The fluidic probe exhibits excellent flexibility, deployability and absorptive capacity. The enhanced absorptive capacity is due to the fluid absorption via capillary action of the nano-pores and fluid transport via the micro-pores. The probes can also be formed so as to be remotely controlled by electromagnetic fields and thus be used in a hands-free fashion. With these probes, the paradigm of a stationary microfluidic platform can be shifted to include flexible structures that can include multiple microfluidic sensors in a single fibrous probe.

Abstract: Disclosed are membranes formed from self-assembling diblock copolymers of the formula (I): wherein R1-R4, n, and m are as described herein, which find use in preparing porous membranes. Embodiments of the membranes contain the diblock copolymer that self-assembles into a cylindrical morphology. Also disclosed is a method of preparing such a membrane which involves hybrid casting a polymer solution containing the diblock copolymer to obtain a thin film, followed by evaporation of some of the solvent from the thin film, and coagulating the resulting this film in a bath containing a nonsolvent or poor solvent for the diblock copolymer.

Abstract: Disclosed are membranes formed from self-assembling block copolymers, for example, a diblock copolymer of the formula (I): wherein R1-R4, n, and m are as described herein, which find use in preparing nanoporous membranes. Embodiments of the membranes contain the block copolymer that self-assembles into a cylindrical morphology. Also disclosed is a method of preparing such membrane which involves hybrid casting a polymer solution containing the block copolymer to obtain a thin film, followed by evaporation of some of the solvent from the thin film, and coagulating the resulting this film in a bath containing a nonsolvent or poor solvent for the block copolymer.

Abstract: The invention relates to a method for production of polymeric nanofibers, in which polymeric nanofibers are created due to the action of force of an electric field on solution or melt of a polymer, which is located on the surface of a spinning electrode, whereby the electric field for electrostatic spinning is created alternately between the spinning electrode (1), to which is supplied alternating voltage, and ions (30, 31) of air and/or gas generated and/or supplied to proximity of the spinning electrode (1), whereby according to the phase of the alternating voltage on the spinning electrode (1) polymeric nanofibers with an electric charge of opposite polarity and/or with segments with an electric charge of opposite polarity are created, which after their creation cluster together under the influence of the electrostatic forces into linear formation in the form of a tow or a band, which moves freely in space in direction of gradient of the electric fields away from the spinning electrode (1).

Abstract: A method of nanofibers production from a polymer solution uses electrostatic spinning in an electric field created by a potential difference between a charged electrode and a counter electrode. The polymer solution for spinning is supplied into the electric field using the surface of a rotating charged electrode. On a part of the circumference of the charged electrode near to the counter electrode, a spinning surface is created for attaining a high spinning capacity. In a device for carrying out the method, the charged electrode is pivoted and part of its circumference is immersed in the polymer solution. The free part of the circumference of the charged electrode is positioned opposite the counter electrode.

Abstract: The invention relates to a method of nanofibres production from a polymer solution using electrostatic spinning in an electric field created by a potential difference between a charged electrode and a counter electrode. The polymer solution (2) is for spinning supplied into the electric field using the surface of the rotating charged electrode (30), while on a part of the circumference of the charged electrode (30) near to the counter electrode (40) is a spinning surface created, by which is a high spinning capacity reached. Further the invention relates to a device for carrying out the method, where the charged electrode (30) is pivoted and by its (bottom) part of its circumference it is immersed in the polymer solution (2), while against the free part of the circumference of the charged electrode (30) is positioned the counter electrode (40).