Patents by Inventor David M. Altshuler

David M. Altshuler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATMENT FOR CYSTIC FIBROSIS
    Publication number: 20220047564
    Abstract: This application describes methods of treating cystic fibrosis or a CFTR mediated disease comprising administering Compound I or a pharmaceutically acceptable salt thereof. (I) The application also describes pharmaceutical compositions comprising Compound I or a pharmaceutically acceptable salt thereof and optionally comprising one or more additional CFTR modulating agents.
    Type: Application
    Filed: November 13, 2019
    Publication date: February 17, 2022
    Inventors: David M. ALTSHULER, Corey Don ANDERSON, Bartlomiej BOREK, Weichao George CHEN, Jeremy J. CLEMENS, Thomas CLEVELAND, Timothy Richard COON, Bryan FRIEMAN, Peter GROOTENHUIS, Sara Sabina HADIDA RUAH, Brian J. HARE, Reshma KEWALRAMANI, Jason McCARTNEY, Mark Thomas MILLER, Prasuna PARASELLI, Fabrice PIERRE, Sarah M. ROBERTSON, Patrick R. SOSNAY, Sara E. SWIFT, Fredrick VAN GOOR, Tim YOUNG, Jinglan ZHOU
  • Pre-selection and isolation of single nucleotide polymorphisms
    Publication number: 20040203032
    Abstract: Novel methods of reproducibly determining a limited population of polymorphisms are disclosed.
    Type: Application
    Filed: December 23, 2003
    Publication date: October 14, 2004
    Applicants: Whitehead Institute for Biomedical Research, The General Hospital Corporation
    Inventors: Eric S. Lander, David M. Altshuler, Victor J. Pollara, Christopher Cowles
  • Association of protein kinase C zeta polymorphisms with diabetes
    Publication number: 20030175797
    Abstract: A central role for the gene encoding protein kinase C zeta in diabetes and perhaps in related disorders is disclosed. Use of single nucleotide polymorphisms in the protein kinase C zeta gene for diagnosis, prediction of clinical course and treatment response, development of new treatments and development of cell-culture based and animal models for research and treatment are disclosed.
    Type: Application
    Filed: May 13, 2003
    Publication date: September 18, 2003
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: David M. Altshuler, Joel N. Hirschhorn, Eric S. Lander
  • Haplotype map of the human genome and uses therefor
    Publication number: 20030170665
    Abstract: A method of producing a haplotype map which can be used to select an optimal set of single nucleotide polymorphic sites for examination in a subsequent genotyping study is disclosed, along with the map so produced.
    Type: Application
    Filed: August 5, 2002
    Publication date: September 11, 2003
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Mark J. Daly, David M. Altshuler, Eric S. Lander, John D. Rioux, Stacey B. Gabriel, Stephen Schaffner
  • Association of protein kinase C zeta polymorphisms with diabetes
    Patent number: 6562574
    Abstract: A central role for the gene encoding protein kinase C zeta in diabetes and perhaps in related disorders is disclosed. Use of single nucleotide polymorphisms in the protein kinase C zeta gene for diagnosis, prediction of clinical course and treatment response, development of new treatments and development of cell-culture based and animal models for research and treatment are disclosed.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: May 13, 2003
    Assignees: Whitehead Institute for Biomedical Research, The General Hospital Corporation
    Inventors: David M. Altshuler, Joel N. Hirschhorn, Eric S. Lander
  • Association of protein kinase C zeta polymorphisms with diabetes
    Publication number: 20020137048
    Abstract: A central role for the gene encoding protein kinase C zeta in diabetes and perhaps in related disorders is disclosed. Use of single nucleotide polymorphisms in the protein kinase C zeta gene for diagnosis, prediction of clinical course and treatment response, development of new treatments and development of cell-culture based and animal models for research and treatment are disclosed.
    Type: Application
    Filed: April 25, 2001
    Publication date: September 26, 2002
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: David M. Altshuler, Joel N. Hirschhorn, Eric S. Lander