Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: A storage rack assembly including a tailgate having a recess formed on an interior surface thereof, and a storage rack. The storage rack includes a crossbar, and a pair of support arms having a first end attached to the crossbar and an opposite second end pivotally attached to the interior surface of the tailgate. The pair of support arms are provided on opposite ends of the crossbar. The storage rack is positionable between a stowed position in which the crossbar and the pair of support arms are positioned within the recess of the tailgate, and a use position in which the crossbar and the pair of support arms are positioned out of the recess of the tailgate.

Abstract: A storage rack assembly including a tailgate having a recess formed on an interior surface thereof, and a storage rack. The storage rack includes a crossbar, and a pair of support arms having a first end attached to the crossbar and an opposite second end pivotally attached to the interior surface of the tailgate. The pair of support arms are provided on opposite ends of the crossbar. The storage rack is positionable between a stowed position in which the crossbar and the pair of support arms are positioned within the recess of the tailgate, and a use position in which the crossbar and the pair of support arms are positioned out of the recess of the tailgate.

Abstract: Doors for motor vehicles include door trim panel assemblies having multiple door trim panels held together at attachment points. A door trim panel includes a weakened perimeter formed from a series of apertures in the panel, creating a predetermined breakaway point where the assembly will rupture in the event a load is applied. Methods for tuning the durability of a trim panel assembly include a repeatable cycle in which pins are selected and inserted in a mold at varying positions. During injection molding, the pins form apertures to create a predetermined breakaway point. Changing the size, shape, and location of the pins allows tuning of the durability and properties of the breakaway point. Injection molds have variable pin placement capability to facilitate the method.

Abstract: Doors for motor vehicles include door trim panel assemblies having multiple door trim panels held together at attachment points. A door trim panel includes a weakened perimeter formed from a series of apertures in the panel, creating a predetermined breakaway point where the assembly will rupture in the event a load is applied. Methods for tuning the durability of a trim panel assembly include a repeatable cycle in which pins are selected and inserted in a mold at varying positions. During injection molding, the pins form apertures to create a predetermined breakaway point. Changing the size, shape, and location of the pins allows tuning of the durability and properties of the breakaway point. Injection molds have variable pin placement capability to facilitate the method.

Abstract: An electronic faucet is provided that includes a spout having a passageway configured to conduct fluid flow through the spout, an electrically operable valve coupled to the passageway, and a capacitive sensor coupled to the faucet. A controller may dynamically change on/off thresholds and monitor a stability signal to determine when to turn off the electrically operable valve.

Abstract: An electronic faucet is provided that includes a spout having a passageway configured to conduct fluid flow through the spout, an electrically operable valve coupled to the passageway, and a capacitive sensor coupled to the faucet. A controller may dynamically change on/off thresholds and monitor a stability signal to determine when to turn off the electrically operable valve.

Abstract: A faucet includes a spout and a manual handle that controls a manual valve located in a passageway that conducts fluid flow through the spout. An electrically operable valve is also located within the passageway. The faucet also includes an insulator located between the spout and the manual handle so that the spout is electrically isolated from the manual handle, a first touch sensor on the manual valve handle, a second touch sensor on the spout, and a capacitive sensor directly coupled to one of the first and second touch sensors and capacitively coupled to the other of the first and second touch sensors. The faucet further includes a controller coupled to the capacitive sensor. The controller monitors an output signal from the capacitive sensor to detect touching of the spout and the manual valve handle. The controller is also coupled to the electrically operable valve to control the electrically operable valve in response to the output signal from the capacitive sensor.

Abstract: An electronic faucet is provided that includes a spout having a passageway configured to conduct fluid flow through the spout, an electrically operable valve coupled to the passageway, and a capacitive sensor coupled to the faucet. A controller may dynamically change on/off thresholds and monitor a stability signal to determine when to turn off the electrically operable valve.

Abstract: A faucet includes a spout, a handle, and a capacitive sensor operably coupled to at least one of the spout and the handle. An electrically operable valve is configured to control water flow through the spout. A mode indicator includes a light emitting device configured to provide an indication of a plurality of modes of operation of the faucet.

Abstract: An electronic faucet is provided that includes a spout having a passageway configured to conduct fluid flow through the spout, an electrically operable valve coupled to the passageway, and a capacitive sensor coupled to the faucet. A controller may dynamically change on/off thresholds and monitor a stability signal to determine when to turn off the electrically operable valve.

Abstract: A fluid delivery apparatus includes a spout (12) located adjacent a sink basin (16). A fluid supply conduit (14) is supported by the spout (12). Capacitive sensors (29) and (41) are provided on the spout (12) and sink basin (16), respectively. A controller (26) is coupled to the capacitive sensors (29, 41) to control the amount of fluid supplied to the fluid supply conduit (14) based on outputs from the capacitive sensors (29, 41).

Abstract: A faucet includes a proximity sensor, a logical control, a handle, a spout, and a touch control operably coupled to at least one of the spout and the handle.

Abstract: A faucet includes a spout and a manual handle that controls a manual valve located in a passageway that conducts fluid flow through the spout. An electrically operable valve is also located within the passageway. The faucet also includes an insulator located between the spout and the manual handle so that the spout is electrically isolated from the manual handle, a first touch sensor on the manual valve handle, a second touch sensor on the spout, and a capacitive sensor directly coupled to one of the first and second touch sensors and capacitively coupled to the other of the first and second touch sensors. The faucet further includes a controller coupled to the capacitive sensor. The controller monitors an output signal from the capacitive sensor to detect touching of the spout and the manual valve handle. The controller is also coupled to the electrically operable valve to control the electrically operable valve in response to the output signal from the capacitive sensor.

Abstract: A faucet includes a spout, a handle, and a capacitive sensor operably coupled to at least one of the spout and the handle. An electrically operable valve is configured to control water flow through the spout. A mode indicator includes a light emitting device configured to provide an indication of a plurality of modes of operation of the faucet.

Abstract: A faucet (10) includes a spout (12), a passageway that conducts fluid flow through the spout (12), a electrically operable valve (22) located within the passageway, a manual valve (20) located within the passageway in series with the electrically operable valve, and a manual handle (14) that controls the manual valve (20). The faucet (10) also includes a first touch sensor (26) on the manual valve handle (14), a second touch sensor (28) on the spout (12), a capacitive sensor (30) directly coupled to one of the first and second touch sensors (26, 28) and capacitively coupled to the other of the first and second touch sensors (26, 28), and a controller (24) coupled to the capacitive sensor (30). The controller (24) is configured to monitor the output signal from the capacitive sensor (30) and to distinguish between a user tapping one of the spout (12) and the manual valve handle (14), a user grabbing the spout (12), and a user grabbing the manual valve handle (14).

Abstract: A faucet includes a proximity sensor, a logical control, a handle, a spout, and a touch control operably coupled to at least one of the spout and the handle. The logical control includes a mode controller that changes the faucet between a first mode and a second mode in response to substantially simultaneous touching of the spout and the handle.

Abstract: A fluid delivery apparatus comprises a spout, a fluid supply conduit supported by the spout, a valve assembly to supply fluid through the fluid supply conduit, and a capacitive touch sensor. The capacitive touch sensor is coupled to a controller. The controller is also coupled to the valve assembly. The controller is configured to detect a user touching the sensor and to control flow of fluid through the fluid supply conduit.

Abstract: A faucet includes a proximity sensor, a logical control, a handle, a spout, and a touch control operably coupled to at least one of the spout and the handle.

Abstract: A faucet arrangement includes a sensing device for sensing a presence of a user of a spout. The sensing device includes an infrared emitter installed such that a direction of emission of the emitter is oriented an angle of approximately between 5 and 15 degrees relative to a vertical direction. A receiver receives a diffused infrared energy from the emitter. A control device is in communication with the receiver and controls a flow of liquid through the spout dependent upon an angle at which the diffused infrared energy is received by the receiver.