Patents by Inventor David M. Burns

David M. Burns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRROLOPYRIMIDINE DERIVATIVES AS TAM INHIBITORS
    Publication number: 20190031663
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Application
    Filed: July 11, 2018
    Publication date: January 31, 2019
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Joseph Glenn, Chunhong He, Taisheng Huang, Song Mei, Jun Pan, Xiaozhao Wang, Yingda Ye
  • PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS
    Publication number: 20180327412
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Application
    Filed: May 4, 2018
    Publication date: November 15, 2018
    Inventors: Yun-Long Li, Xiaozhao Wang, Joseph Barbosa, David M. Burns, Hao Feng, Joseph Glenn, Chunhong He, Taisheng Huang, Song Mei, Jincong Zhuo
  • Imidazotriaines and Imidazopyrimidines as Kinase Inhibitors
    Publication number: 20180282340
    Abstract: The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways.
    Type: Application
    Filed: March 20, 2018
    Publication date: October 4, 2018
    Inventors: Jincong Zhuo, Meizhong Xu, Chunhong He, Colin Zhang, Ding-Quan Qian, David M. Burns, Yun-Long Li, Brian Metcalf, Wenqing Yao
  • Pyrrolopyrimidine derivatives as TAM inhibitors
    Patent number: 10053465
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: August 21, 2018
    Assignee: Incyte Corporation
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Joseph Glenn, Chunhong He, Taisheng Huang, Song Mei, Jun Pan, Xiaozhao Wang, Yingda Ye
  • Bicyclic fused pyrimidine compounds as TAM inhibitors
    Patent number: 10005788
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: June 26, 2018
    Assignee: Incyte Corporation
    Inventors: Yun-Long Li, David M. Burns
  • Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors
    Patent number: 10000507
    Abstract: The present disclosure describes furo- and thieno-pyridine carboxamide compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: June 19, 2018
    Assignee: Incyte Corporation
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Taisheng Huang, Song Mei, Jun Pan, Hai-Fen Ye, Wenyu Zhu, Maria Rafalski, Anlai Wang, Chu-Biao Xue
  • Imidazotriazines and imidazopyrimidines as kinase inhibitors
    Patent number: 9944645
    Abstract: The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: April 17, 2018
    Assignees: Incyte Corporation, Incyte Holdings Corporation
    Inventors: Jincong Zhuo, Meizhong Xu, Chunhong He, Colin Zhang, Ding-Quan Qian, David M. Burns, Yun-Long Li, Brian Metcalf, Wenqing Yao
  • BICYCLIC FUSED PYRIMIDINE COMPOUNDS AS TAM INHIBITORS
    Publication number: 20180009815
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Application
    Filed: June 16, 2017
    Publication date: January 11, 2018
    Inventors: Yun-Long Li, David M. Burns
  • Heterocyclic compounds and uses thereof
    Patent number: 9840503
    Abstract: The present disclosure relates to heterocyclic compounds, and pharmaceutical compositions of the same, that are inhibitors of the TAM protein kinases and are useful in the treatment of TAM-associated diseases such as cancer.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: December 12, 2017
    Assignee: Incyte Corporation
    Inventors: Yaping Sun, Yun-Long Li, David M. Burns
  • PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS
    Publication number: 20170275290
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Application
    Filed: March 27, 2017
    Publication date: September 28, 2017
    Inventors: Yun-Long Li, Xiaozhao Wang, Joseph Barbosa, David M. Burns, Hao Feng, Joseph Glenn, Chunhong He, Taisheng Huang, Song Mei, Jincong Zhuo
  • AZETIDINYL PHENYL, PYRIDYL OR PYRAZINYL CARBOXAMIDE DERIVATIVES AS JAK INHIBITORS
    Publication number: 20170253598
    Abstract: The present invention provides azetidinyl phenyl, pyridyl, or pyrazinyl carboxamide derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase (JAKs) and are useful in the treatment of diseases related to the activity of JAK including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
    Type: Application
    Filed: February 17, 2017
    Publication date: September 7, 2017
    Inventors: Wenqing Yao, David M. Burns, Jincong Zhuo
  • FILMS INCLUDING TRIAZINE-BASED ULTRAVIOLET ABSORBERS
    Publication number: 20170254926
    Abstract: The present application generally relates to EAA films including at least one triazine-based ultraviolet absorber. The present application also generally relates to retroreflective sheeting including an EAA film including a triazine-based ultraviolet absorber. One embodiments of the present application relates to a film, comprising poly(ethylene-co-acrylic acid) and a triazine-based UVA. Another embodiment of the present application relates to retroreflective sheeting, comprising: a plurality of cube corner elements; and a body layer adjacent to the cube corner elements, the body layer including poly(ethylene-co-acrylic acid) and a triazine-based UVA.
    Type: Application
    Filed: May 23, 2017
    Publication date: September 7, 2017
    Inventors: David W. Meitz, Bimal V. Thakkar, David M. Burns, David B. Olson, Lee A. Pavelka
  • Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors
    Patent number: 9708333
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: July 18, 2017
    Assignee: Incyte Corporation
    Inventors: Yun-Long Li, David M. Burns
  • FURO- AND THIENO-PYRIDINE CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS
    Publication number: 20170190716
    Abstract: The present disclosure describes furo- and thieno-pyridine carboxamide compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Application
    Filed: December 15, 2016
    Publication date: July 6, 2017
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Taisheng Huang, Song Mei, Jun Pan, Oleg Vechorkin, Hai-Fen Ye, Wenyu Zhu, Maria Rafalski, Anlai Wang, Chu-Biao Xue
  • Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors
    Patent number: 9676750
    Abstract: The present disclosure describes bicyclic aromatic carboxamide derivatives, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: June 13, 2017
    Assignees: Incyte Corporation, Incyte Holdings Corporation
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Chu-Biao Xue, Anlai Wang, Jun Pan
  • Films including triazine-based ultraviolet absorbers
    Patent number: 9658363
    Abstract: The present application generally relates to EAA films including at least one triazine-based ultraviolet absorber. The present application also generally related to retroreflective sheeting including an EAA film including a triazine-based ultraviolet absorber. One embodiments of the present application relates to a film, comprising poly(ethylene-co-acrylic acid) and a triazine-based UVA. Another embodiment of the present application relates to retroreflective sheeting, comprising: a plurality of cube corner elements; and a body layer adjacent to the cube corner elements, the body layer including poly(ethylene-co-acrylic acid) and a triazine-based UVA.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: May 23, 2017
    Assignee: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: David W. Meitz, Bimal V. Thakkar, David M. Burns, David B. Olson, Lee A. Pavelka
  • PYRROLOPYRIMIDINE DERIVATIVES AS TAM INHIBITORS
    Publication number: 20170057965
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Application
    Filed: August 25, 2016
    Publication date: March 2, 2017
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Joseph Glenn, Chunhong He, Taisheng Huang, Song Mei, Jun Pan, Xiaozhao Wang, Yingda Ye
  • BICYCLIC FUSED PYRIMIDINE COMPOUNDS AS TAM INHIBITORS
    Publication number: 20170044164
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Application
    Filed: August 11, 2016
    Publication date: February 16, 2017
    Inventors: Yun-Long Li, David M. Burns, Joseph Glenn
  • Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors
    Patent number: 9556197
    Abstract: The present disclosure describes furo- and thieno-pyridine carboxamide compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: January 31, 2017
    Assignee: Incyte Corporation
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Taisheng Huang, Song Mei, Jun Pan, Oleg Vechorkin, Hai-Fen Ye, Wenyu Zhu, Maria Rafalski, Anlai Wang, Chu-Biao Xue
  • HETEROCYCLIC COMPOUNDS AND USES THEREOF
    Publication number: 20160333008
    Abstract: The present disclosure relates to heterocyclic compounds, and pharmaceutical compositions of the same, that are inhibitors of the TAM protein kinases and are useful in the treatment of TAM-associated diseases such as cancer.
    Type: Application
    Filed: May 10, 2016
    Publication date: November 17, 2016
    Inventors: Yaping Sun, Yun-Long Li, David M. Burns