Abstract: A method for the real-time visualization and detection of extravasated and or infiltrated fluid and substances, including blood, that occur near the cannulation site of an injection is described wherein illumination or transillumination with near infrared light is used to image the contrast in real-time between absorbing and nonabsorbing subdermal and intradermal structures of blood vessels and remaining surrounding tissue, foreign substances and other structures in order to establish a baseline image of the body area of interest, and any new image is monitored and compared with the baseline image to detect the extravasation and/or infiltration of fluids and substances, including blood, around a vein or artery into the subdermal or intradermal tissue.

Abstract: A disposable light source device for the non-invasive visualization of veins, arteries or other subcutaneous structures of and objects in the body, or for facilitating and monitoring intravenous insertion or extraction of fluids, including a conforming layer for interfacing and optically coupling with the body surface, and adhering the device to the body portion, and a main light source for directing near infrared light through the conforming layer to illuminate the body. The disposable light source device can also include a light transmissive and electrically insulative layer that is disposed between and electrically insulates the main light source from the body-contacting conforming layer. The disposable light source device can also include a proximity sensor that controls activation of the first light source such that the light source is on only when the conforming layer is brought into proximity to the body surface.

Abstract: A multi-layered structure in the form of a disposable patch is described for supporting a light source and useful in conjunction with procedures for the non-invasive visualization of veins, arteries or other subcutaneous structures of the body or for facilitating intravenous insertion or extraction of fluids, medication or the like, which in a representative embodiment includes a coupling layer for interfacing and optically coupling with the body surface and conforming to the surface topography of the body portion of interest, a ring for supporting a light source, and a reflective layer between the source and coupling layer for redirecting light reflected from the body surface back through the coupling layer.

Abstract: A method for the real-time visualization and detection of extravasated and or infiltrated fluid and substances, including blood, that occur near the cannulation site of an injection is described wherein illumination or transillumination with near infrared light is used to image the contrast in real-time between absorbing and nonabsorbing subdermal and intradermal structures of blood vessels and remaining surrouding tissue, foreign substances and other structures in order to establish a baseline image of the body area of interest, and any new image is monitored and compared with the baseline image to detect the extravasation and/or infiltration of fluids and substances, including blood, around a vein or artery into the subdermal or intradermal tissue.