Abstract: In general, the invention features a novel CBM32-derived affinity scaffold. In certain embodiments, the scaffold comprises two types of regions: constant regions (CRs) and variable loop regions (VLRs) as depicted in the structure in FIG. 1. We have discovered that the CRs provide structural features that enable overall conformational stability while the intervening sequences corresponding to VLRs tolerate amino acid sequence randomization.

Abstract: In general, the invention features a novel CBM32-derived affinity scaffold. In certain embodiments, the scaffold comprises two types of regions: constant regions (CRs) and variable loop regions (VLRs) as depicted in the structure in FIG. 1. We have discovered that the CRs provide structural features that enable overall conformational stability while the intervening sequences corresponding to VLRs tolerate amino acid sequence randomization.

Abstract: The invention provides methods and webpages for commerce and information exchange wherein a seller offers to consumers one or more products or services on a webpage that facilitates the exchange of information (e.g., product reviews, rankings, and applications data) and compensation between the seller and consumers or between consumers.

Abstract: Eukaryotic RNA polymerase II holoenzymes that contain RNA polymerase II and one or more regulatory proteins are described. These holoenzymes selectively initiate transcription in vitro when supplemented with general transcription factors. The regulatory proteins act positively and negatively to regulate transcription initiation, at least in part, via functional interactions with RNA polymerase II.

Abstract: Eukaryotic RNA polymerase II holoenzymes that contain RNA polymerase II and one or more regulatory SRB proteins are described. These holoenzymes will selectively initiate transcription in vitro when supplemented with general transcription factors such as TATA-binding protein (TBP) and factor a (TFIIE). The SRB proteins act positively and negatively to regulate transcription initiation, at least in part, via functional interactions with RNA polymerase II.

Abstract: A removable marking sticker is provided for a Petri dish for correlating a cell on a Petri dish with a specific location. The sticker includes a backing substrate and a removable sticker element having an adhesive surface immediately adjacent to the backing substrate. The sticker has a plurality of dividing lines designated thereon in a predetermined configuration so as to define a plurality of locations.

Abstract: A document holder comprising two supporting members. Each supporting member includes an upper member which is aligned with an upper part of the document, a lower member which is aligned with a lower part of the document, and a resilient member which connects the upper portion to the lower portion and which exerts a bias force to make the upper portion substantially colinear with the lower portion. The newspaper is inserted between the two supporting members such that the horizontal crease of the document is aligned or overlaps with the resilient member. The resilient member allows the document to be folded up into a smaller size to facilitate reading, and exerts a bias force to open the document after a page has been read to facilitate page turning. The supporting members may include one or more mortise and tenon joints which allow the supporting members to be disengaged and folded for compact storage.

Abstract: A eukaryotic, global negative regulator of class II transcription, DNA sequences encoding the negative regulator and results demonstrating the activity of the purified negative regulator protein to repress class II transcription are described.