Patents by Inventor David M. Chenoweth

David M. Chenoweth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of drug design and optimisation utilizing stereochemical mimicry
    Patent number: 10591461
    Abstract: The invention relates to a method of designing or optimizing a drug candidate by making stereodynamic derivatives as well as novel derivatives of Glyx-13 with improved biological and pharmacological properties.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: March 17, 2020
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventor: David M. Chenoweth
  • Imaging agents and methods of identifying same
    Patent number: 10487089
    Abstract: The present invention includes a novel method capable of identifying a compound as an imaging agent using a DAZAX-based scaffold or derivative thereof. The present invention further includes novel imaging agents. The present invention further includes a method of modifying a DAZAX-based scaffold or derivative thereof. The present invention further includes a method for imaging a sample.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: November 26, 2019
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: David M. Chenoweth, Robert-Andre F. Rarig, Mai N. Tran
  • METHOD OF DRUG DESIGN AND OPTIMISATION UTILIZING STEREOCHEMICAL MIMICRY
    Publication number: 20190154662
    Abstract: The invention relates to a method of designing or optimizing a drug candidate by making stereodynamic derivatives as well as novel derivatives of Glyx-13 with improved biological and pharmacological properties.
    Type: Application
    Filed: April 27, 2017
    Publication date: May 23, 2019
    Inventor: David M. CHENOWETH
  • Aza-amino acid collagen compounds
    Patent number: 10174083
    Abstract: The invention relates to aza-amino acid backbone-modified biomimetic collagens and general methods for designing and making biomimetic materials and molecular mimics.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: January 8, 2019
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: David M. Chenoweth, Yitao Zhang
  • TRIPTYCENE DERIVATIVES FOR NUCLEIC ACID JUNCTION STABILIZATION
    Publication number: 20180265911
    Abstract: The present invention is directed to compositions and methods using triptycene derivatives (TCDs) for three way junctions (TWJs).
    Type: Application
    Filed: September 26, 2016
    Publication date: September 20, 2018
    Inventors: David M. CHENOWETH, Stephanie A. BARROS
  • AZA-AMINO ACID COLLAGEN COMPOUNDS
    Publication number: 20180079785
    Abstract: The invention relates to aza-amino acid backbone-modified biomimetic collagens and general methods for designing and making biomimetic materials and molecular mimics.
    Type: Application
    Filed: April 28, 2017
    Publication date: March 22, 2018
    Inventors: David M. CHENOWETH, Yitao ZHANG
  • New Imaging Agents and Methods of Identifying Same
    Publication number: 20170183356
    Abstract: The present invention includes a novel method capable of identifying a compound as an imaging agent using a DAZAX-based scaffold or derivative thereof. The present invention further includes novel imaging agents. The present invention further includes a method of modifying a DAZAX-based scaffold or derivative thereof. The present invention further includes a method for imaging a sample.
    Type: Application
    Filed: March 20, 2015
    Publication date: June 29, 2017
    Applicant: Thr Trustees of the University of Pennsylvania
    Inventors: David M. Chenoweth, Robert-Andre F. Rarig, Mai N. Tran
  • NANOSTRUCTURED DEVICES INCLUDING ANALYTE DETECTORS, AND RELATED METHODS
    Publication number: 20110171629
    Abstract: The present invention provides compositions and devices comprising nanostructure networks, and related methods. The compositions may exhibit enhanced interaction between nanostructures, providing improved device performance (e.g., improved conductivity). In some embodiments, the devices are capable of interacting with various species to produce an observable signal from the device. In some cases, the compositions and devices may be useful in the determination of analytes, including—biological analytes (e.g., DNA, ebola virus, other infective agents, etc.), small, organic analytes, and the like. The embodiments described herein may exhibit high sensitivity and specificity to analytes and may be capable of analyte detection at femtomolar concentrations (e.g., 10 fM).
    Type: Application
    Filed: November 4, 2010
    Publication date: July 14, 2011
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, Yossef Weizmann, David M. Chenoweth