Patents by Inventor David M. Duckworth

David M. Duckworth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Seven trans-membrane receptor-Fitz2
    Publication number: 20020143149
    Abstract: Fitz2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Fitz2 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: September 10, 2001
    Publication date: October 3, 2002
    Inventors: David M. Duckworth, Mahanandeeshwar Gattu, Tania Testa, Lisa Vawter
  • Antiviral purine compounds
    Patent number: 5247085
    Abstract: Compounds of formula (I), and pharmaceutically acceptable salts thereof ##STR1## wherein R.sub.1 is hydroxy, amino, chloro or OR.sub.7 whereinR.sub.7 is C.sub.1-6 alkyl, phenyl or phenyl C.sub.1-2 alkyl either of which phenyl moieties may be substituted by one or two substituents selected from halo, C.sub.1-4 alkyl or C.sub.1-4 alkoxy;R.sub.2 is amino or, when R.sub.1 is hydroxy or amino, R.sub.2 may also be hydrogen;R.sub.3 is hydrogen, hydroxymethyl or acyloxymethyl;R.sub.4 is a group of formula: ##STR2## R.sub.5 and R.sub.6 are independently selected from hydrogen, C.sub.1-6 alkyl and optionally substituted phenyl; orR.sub.3 and R.sub.4 together are: ##STR3## wherein R.sub.6 is as defined above;having antiviral activity, to processes for their preparation and their use as pharmaceuticals.
    Type: Grant
    Filed: May 29, 1992
    Date of Patent: September 21, 1993
    Assignee: Beecham Group p.l.c.
    Inventors: Michael R. Harnden, David M. Duckworth
  • Antiviral phosphonylalkoxy purines
    Patent number: 5166198
    Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof: ##STR1## wherein R.sub.1 is hydroxy or amino;R.sub.2 is hydrogen or amino;R.sub.3 is hydrogen, hydroxymethyl or acyloxymethyl;R.sub.4 is hydrogen or (when R.sub.3 =H and Z is a bond or CH.sub.2) hydroxy, acyloxy, hydroxymethyl or acyloxymethyl;Z is a bond, or a group CHR.sub.8 wherein R.sub.8 is hydrogen, or (when R.sub.3 =R.sub.4 =H), R.sub.8 is hydroxy, acyloxy, hydroxymethyl or acyloxymethyl;R.sub.5 is a group of formula: ##STR2## wherein R.sub.6 and R.sub.7 are independently selected from hydrogen,C.sub.1-6 alkyl and optionally substituted phenyl.
    Type: Grant
    Filed: March 28, 1990
    Date of Patent: November 24, 1992
    Assignee: Beecham p.l.c.
    Inventors: Michael R. Harnden, David M. Duckworth, Halina T. Serafinowska
  • Secondary amines and compositions for treatment of hypoglycaemia or obesity
    Patent number: 4382958
    Abstract: A compound of formula (I): ##STR1## or a salt thereof; wherein R.sup.1 is hydrogen, methyl or ethyl; R.sup.2 is hydrogen, methyl or ethyl; R.sup.3 is hydrogen, fluorine, chlorine, bromine or trifluoromethyl; each of R.sup.4 and R.sup.5 is hydrogen, fluorine, chlorine, bromine, C.sub.1-6 alkyl or C.sub.1-6 alkoxy; n is 1 or 2; and X is C.sub.1-12 straight or branched alkylene, and salts thereof, are anti-obesity, hypoglycaemic, anti-inflammatory and platelet aggregation inhibiting agents.
    Type: Grant
    Filed: November 9, 1981
    Date of Patent: May 10, 1983
    Assignee: Beecham Group Limited
    Inventor: David M. Duckworth