Abstract: Provided herein are phosphodiesterase 4 (PDE4) degraders, e.g., a compound of Formula (I) or (IA), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a PDE4-mediated disease, disorder, or condition.

Abstract: A method for assembling a direct drive generator assembly includes the steps of placing a rotor over a stator, leaving a gap therebetween. A magnetic hub is assembled using adjacent columns of magnets having opposed orientation, and placed in the air gap. Application of an input torque to generate cogging torque in first direction that offsets coggery torque in second direction.

Abstract: A method for assembling a direct drive generator assembly includes the steps of placing a rotor over a stator, leaving a gap therebetween. A magnetic hub is assembled using adjacent columns of magnets having opposed orientation, and placed in the air gap. Application of an input torque to generate cogging torque in first direction that offsets coggery torque in second direction.

Abstract: A direct-drive generator and assembly procedure for that generator include a permanent magnet assembly that is partitioned and assembled piece-by-piece after the rotor and stator have been attached. The magnets are attached to a plate in columns, and adjacent columns have a N-S orientation. The air gap between the rotor and stator is variable, and application of an input torque produces a first cogging torque in a first direction due to the variable air gap that offsets a second cogging torque in a second opposite direction.

Abstract: The invention is a generator and cooling mechanism. The generator includes a rotor comprising a shaft with a skewed alignment of magnets on a ring, a stator of toothed laminations with coils wound around the teeth, and a housing with cooling chambers. The housing has annular subchambers arranged successively along the length of the generator in such a way that cooling fluid must flow to the opposite side of the generator to pass into the next chamber. Because the housing is highly heat conductive, this structure of annular subchambers increases the uniformity of the fluid temperature.

Abstract: An electric motor including a stator, a rotor, and a housing adapted to support the stator and the rotor is provided. The stator includes a stator core, a first and second lamination stack, a flux tube extending therethrough, and windings on the stator core. The rotor includes a hub having an inner surface, a magnet coupled to the hub inner surface, and a shaft received in the stator core for rotation of the rotor relative to the stator about the longitudinal axis of the shaft.

Abstract: A method for varying motor output using magnets of different fluxes includes manufacturing standardized parts, ascertaining desired motor output, selecting from a group of interchangeable magnets to provide the desired output, and assembling a motor with the selected magnets and standardized parts such that the desired output is provided. Additionally, a motor kit including a rotor configured to accommodate magnets of varying residual induction values and lengths, a stator configured to operate with the rotor, and a plurality of interchangeable magnets with different residual induction values and lengths.

Abstract: An energy efficient low-power integral electronically commutated fan motor and control circuit assembly mounted on a circuit board for use in refrigerators utilizing a Hall sensor to provide positional control signals for sequential energization of the windings with the Hall sensor energization being pulsed, and the motor stator windings energized only during a portion of the period, when rotational torque produced by the energization is greatest in order to reduce the power input to the assembly. Integrally molded multi-function components including the coil bobbin, ground pin, Hall sensor holder, motor bearing oil well covers, and assembly housing provide positioning, support, and securing assistance along with electrical and magnetic operative connections and positioning.

Abstract: An electric motor including a stator, a rotor, and a housing adapted to support the stator and the rotor is provided. The stator includes a stator core, a first and second lamination stack, a flux tube extending therethrough, and windings on the stator core. The rotor includes a hub having an inner surface, a magnet coupled to the hub inner surface, and a shaft received in the stator core for rotation of the rotor relative to the stator about the longitudinal axis of the shaft.

Abstract: A method for varying motor output using magnets of different fluxes includes manufacturing standardized parts, ascertaining desired motor output, selecting from a group of interchangeable magnets to provide the desired output, and assembling a motor with the selected magnets and standardized parts such that the desired output is provided. Additionally, a motor kit including a rotor configured to accommodate magnets of varying residual induction values and lengths, a stator configured to operate with the rotor, and a plurality of interchangeable magnets with different residual induction values and lengths.

Abstract: Methods and apparatus for minimizing electrical machine vibration are described. In an exemplary embodiment of the method, power is applied to the motor under microprocessor control such that a pulse modulated current profile is applied to the motor which in turn controls the amount of torque generated by the motor. By adjusting current profiles, torque generation is controlled, and vibration and noise are eliminated.

Abstract: An energy efficient low-power integral electronically commutated fan motor and control circuit assembly mounted on a circuit board for use in refrigerators utilizing a Hall sensor to provide positional control signals for sequential energization of the windings with the Hall sensor energization being pulsed, and the motor stator windings energized only during a portion of the period, when rotational torque produced by the energization is greatest in order to reduce the power input to the assembly. Integrally molded multi-function components including the coil bobbin, ground pin, Hall sensor holder, motor bearing oil well covers, and assembly housing provide positioning, support, and securing assistance along with electrical and magnetic operative connections and positioning.

Abstract: An energy efficient low-power integral electronically commutated fan motor and control circuit assembly mounted on a circuit board for use in refrigerators utilizing a Hall sensor to provide positional control signals for sequential energization of the windings with the Hall sensor energization being pulsed, and the motor stator windings energized only during a portion of the period, when rotational torque produced by the energization is greatest in order to reduce the power input to the assembly. Integrally molded multi-function components including the coil bobbin, ground pin, Hall sensor holder, motor bearing oil well covers, and assembly housing provide positioning, support, and securing assistance along with electrical and magnetic operative connections and positioning.

Abstract: A method for facilitating the reduction of transmitted motor noise using a mounting system in a frame. The mounting system includes a motor assembly having an end bell, a mounting bracket including a brace, a plurality of attachment openings, a plurality of leaf springs attached to the brace and an anchor device attached to each leaf spring. Each anchor device includes a fastener opening and a grommet. The leaf springs and grommets are configured to filter and damp noise transmitted from the motor to the frame.

Abstract: An energy efficient low-power integral electronically commutated fan motor and control circuit assembly mounted on a circuit board for use in refrigerators utilizing a Hall sensor to provide positional control signals for sequential energization of the windings with the Hall sensor energization being pulsed, and the motor stator windings energized only during a portion of the period, when rotational torque produced by the energization is greatest in order to reduce the power input to the assembly. Integrally molded multi-function components including the coil bobbin, ground pin, Hall sensor holder, motor bearing oil well covers, and assembly housing provide positioning, support, and securing assistance along with electrical and magnetic operative connections and positioning.

Abstract: A motor speed control circuit generates a half cycle waveform and applies the half-cycle waveform to the motor at a controlled frequency to achieve speed reduction in the motor without motor modification. The circuit includes a rectifier bridge electrically connected to a power source and the motor terminals, a polarity sensing circuit electrically connected to the power source, a frequency reducing circuit coupled to the polarity sensing circuit and a bridge enabling circuit coupled to the frequency reducing circuit and to the rectifier bridge.

Abstract: An energy efficient low-power integral electronically commutated fan motor and control circuit assembly mounted on a circuit board for use in refrigerators utilizing a Hall sensor to provide positional control signals for sequential energization of the windings with the Hall sensor energization being pulsed, and the motor stator windings energized only during a portion of the period, when rotational torque produced by the energization is greatest in order to reduce the power input to the assembly. Integrally molded multi-function components including the coil bobbin, ground pin, Hall sensor holder, motor bearing oil well covers, and assembly housing provide positioning, support, and securing assistance along with electrical and magnetic operative connections and positioning.

Abstract: An inside out motor includes a rotor including a concave member, a shaft defining a longitudinal axis mounted on the concave member and a magnet mounted on an interior surface of the concave member. A bearing receives the shaft for rotatably mounting the rotor. A stator assembly is mounted on said bearing and includes a bobbin mounted generally coaxially with the rotor shaft and having an interior diameter, an exterior diameter, a first axial end and a second axial end. A winding is wound on the bobbin and extends around the axis of the rotor shaft. The winding has a width in a direction parallel to the lengthwise extension of the rotor shaft. Plural separate ferromagnetic members are on each of the first and second axial ends of the bobbin. Each ferromagnetic member has a radially outer leg extending generally between the winding and the magnet.

Abstract: A motor having an external rotor, or "inside out motor" has a split C arrangement of ferromagnetic members which function as the poles of the electromagnet in the motor. The ferromagnetic members are generally C-shaped and mounted on opposite end caps of the motor. The ferromagnetic members on the opposing end caps are angularly offset from each other. The ferromagnetic members on each end cap are also spaced apart from each other, and receive a portion of the motor windings within them. The motor is constructed for assembly using few or no separate fastening devices to secure the components together. In one embodiment, a bearing core serves as the base on which all parts are assembled.

Abstract: A single phase permanent magnet motor includes a rotor, a stator, and a quadrature axis winding positioned out-of-phase from a main winding of the stator for generating an output signal representative of rotor angular position. An integrator can be coupled to the quadrature axis winding for phase retarding the output signal, and a comparator can be coupled to the integrator for detecting zero crossings of the phase retarded output signal to provide a commutation signal. The quadrature axis winding can be positioned about ninety electrical degrees out-of-phase from the main winding of the stator, and the integrator can be adapted to phase retard the output signal by a number of degrees which decreases as a speed of the motor increases. At low speeds the phase retard is preferably at about ninety degrees so that the phase retarded signal becomes in-phase with the main stator winding back EMF voltage.