Patents by Inventor David M. Floyd

David M. Floyd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclopropyl aza prostaglandin analogs
    Patent number: 4965279
    Abstract: Novel cyclopropyl aza prostaglandin analogs are disclosed having the formula ##STR1## wherein A can be carbonyl, sulfonyl or a single bond. These compounds are useful, for example, as thromboxane antagonists.
    Type: Grant
    Filed: November 18, 1988
    Date of Patent: October 23, 1990
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Raj N. Misra, David M. Floyd, Steven E. Hall
  • Benzazepine and benzothiazepine derivatives
    Patent number: 4902684
    Abstract: Vasodilating activity is exhibited by compounds having the formula ##STR1## wherein X can be --S--or --CH.sub.2 --; andR.sub.2 is ##STR2##depending upon the definition of X.
    Type: Grant
    Filed: May 22, 1989
    Date of Patent: February 20, 1990
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David M. Floyd, John T. Hunt, Spencer D. Kimball, John Krapcho, Jagabandhu Das, George C. Rovnyak, Joel C. Barrish
  • Amino substituted benzenepropanols
    Patent number: 4788010
    Abstract: Hypotensive activity is exhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof wherein R.sub.1 is hydrogen or alkyl;R.sub.2 and R.sub.3 are each independently phenyl, substituted phenyl, cycloalkyl, or R.sub.2 is hydrogen and R.sub.3 is heteroaryl;R.sub.4 and R.sub.5 are the same or different and each is hydrogen, hydroxy, alkoxy, alkanoyl or alkyl;R.sub.6 is hydrogen or alkyl; andn is 1, 2, 3 or 4; with the proviso that if R.sub.2 and R.sub.3 are each phenyl, at least one of R.sub.1, R.sub.4, R.sub.5 and R.sub.6 is other than hydrogen.
    Type: Grant
    Filed: April 24, 1985
    Date of Patent: November 29, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David M. Floyd, Spencer D. Kimball, Steven Brandt
  • 3-substituted benzazepines
    Patent number: 4767756
    Abstract: Benzazepine derivatives useful, for example, as cardiovascular agents, are disclosed. These compounds have the general formula ##STR1## and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: July 17, 1987
    Date of Patent: August 30, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Jagabandhu Das, David M. Floyd
  • Sulphonamidothienylcarboxylic acid compounds
    Patent number: 4752613
    Abstract: Compounds represented by the formula ##STR1## wherein X is halogen, lower alkyl, arylalkyl, alkoxy or hydroxy; wherein the phenyl ring is mono or disubstituted, R' is --COOH or ##STR2## wherein R" is lower alkyl or aryl and n and m are independently zero, one, two or three which are potent thromboxane A.sub.2 receptor antagonists.
    Type: Grant
    Filed: August 3, 1987
    Date of Patent: June 21, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David M. Floyd, Philip D. Stein
  • Process for preparing (s)-3-amino-2-oxo-1-azetidinesulfonic acid salts
    Patent number: 4625022
    Abstract: The process of this invention provides for the conversion of amino acid amides having the formula ##STR1## to 3-amino-2-oxo-1-azetidinesulfonic acid salts having the formula ##STR2## wherein one of R.sub.2 and R.sub.3 is hydrogen and the other is hydrogen, alkyl, cycloalkyl, phenyl or substituted phenyl and M.sup..sym. is hydrogen or a cation.
    Type: Grant
    Filed: November 15, 1985
    Date of Patent: November 25, 1986
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David M. Floyd, Alan W. Fritz, Christopher M. Cimarusti
  • Nematicidal isothiazole derivatives
    Patent number: 4539328
    Abstract: Nematicidal 3-aryl-4-amino-5-isothiazole acids, esters and amides of the formula ##STR1## wherein A is selected from hydroxy, alkoxy, phenylmethoxy, and --NHR, where R is hydrogen, alkyl, 2-hydroxyethyl or 2-acetyloxyethyl; andZ is selected from hydrogen, halogen, alkyl, alkoxy, difluoromethoxy, thiomethyl, nitro, amino, and phenyl.
    Type: Grant
    Filed: March 25, 1983
    Date of Patent: September 3, 1985
    Assignee: FMC Corporation
    Inventors: William S. DiMenna, David M. Floyd
  • Sulfamated amino acid amides
    Patent number: 4386034
    Abstract: The process of this invention provides for the conversion of amino acid amides having the formula ##STR1## to 3-amino-2-oxo-1-azetidinesulfonic acid salts having the formula ##STR2## wherein one of R.sub.2 and R.sub.3 is hydrogen and the other is hydrogen, alkyl, cycloalkyl, phenyl or substituted phenyl and M.sup..sym. is hydrogen or a cation.
    Type: Grant
    Filed: February 10, 1982
    Date of Patent: May 31, 1983
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David M. Floyd, Alan W. Fritz, Christopher M. Cimarusti