Patents by Inventor David M. Glover

David M. Glover has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PCNA binding substance
    Patent number: 6613878
    Abstract: Fragments of Fen1 that interact with PCNA are disclosed, together with the use of such fragments or mimetics of Fen1 in methods of screening for compounds useful in treating disorders in which PCNA is implicated. In particular, substances which have the property of binding to PCNA are disclosed, said substances comprising: (i) a fragment of the Fen1 protein containing a peptide of 89 amino acids from the C-terminal region or an active portion thereof; or, (ii) a fragment of the Fen1 protein containing the sequence motif QGRLDxFF; or, (iii) a functional mimetic of said protein fragments; where “x” is preferably the selected form the amino acids S, D or G.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: September 2, 2003
    Assignee: Cyclacel Limited
    Inventors: Lynne S. Cox, David P. Lane, Emma Warbrick, David M. Glover