Abstract: Systems and methods for identifying and removing bias from communications are disclosed. In one embodiment, a method for identifying bias may include: (1) receiving, by a bias identification computer program executed by an electronic device and from a user electronic device, text comprising a plurality of passages; (2) converting, by the bias identification computer program, each of the plurality of passages into a vector; (3) determining, by the bias identification computer program, that a custom entity in a bias category is present in one of the plurality of vectors or in a preceding or subsequent vector using a trained bias identification machine learning engine; and (4) returning, by the bias identification computer program and to the user electronic device, an indication that the one of the plurality of vectors is biased.

Abstract: The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as no more than 12 weeks. In one aspect, the treatment comprises administering at least two direct acting antiviral agents to a subject with HCV infection, wherein the treatment lasts for 12 weeks and does not include administration of either interferon or ribavirin, and said at least two direct acting antiviral agents comprise (a) Compound 1 or a pharmaceutically acceptable salt thereof and (b) Compound 2 or a pharmaceutically acceptable salt thereof.

Abstract: In one example, a method of data restore testing is disclosed. The method may determine whether to validate a request to restore a backup of production data. The request may be for a database backup, a file system backup or another data type. The method may generate a database instance that restores a backup database data if the request is for database data and may generate a file system instance to restore a backup file system if the request is for a backup of a file system. The method may lockdown access to the restored backup, validate the integrity of the restored backup relative to production data. The validation may be based on a checksum of the restored backup and a checksum of the production data, for example.

Abstract: In one example, a system with a processor operable to cause operations to optimize resources based on user-specified parameters is disclosed. A provisioning request to provision resources from multiple resource pools is received. The provisioning request can include the user-specified parameters. The system may determine state data about the resource pools by using an API that interfaces with the resource pools. The system then determines the resource pools that can satisfy the provisioning request based upon the state data and how efficiently each of the resource pools satisfy the provisioning parameters. The system then provisions resources on a resource pool that has been determined to be capable of satisfying the provisioning request.

Abstract: A microfluidic chip for on-chip detection of the presence or absence of a target nucleic acid region in an isolated nucleic acid sample is disclosed. The microfluidic chip includes a nucleic acid entanglement array, an isolated nucleic acid sample immobilized in the nucleic acid entanglement array, and at least one probe specific to a target nucleic acid region. Systems and methods of using the microfluidic chip are disclosed.

Abstract: A method for isolating one or more distinct analyte component from a cell sample is disclosed, as well as processes for testing and analyzing the distinct analyte components. The distinct analyte components include: (i) a total protein fraction; (ii) a plasma membrane protein fraction; (iii) a total RNA fraction; (iv) a cytosolic RNA fraction; (v) a cytosolic protein fraction; (vi) a nuclear RNA fraction; (vii) a nuclear protein fraction; (viii) a chromatin fraction comprising genomic DNA (gDNA); (ix) a gDNA markers fraction. This method involves the use of microfluidic device having a cell capture component and a nucleic acid entanglement component, where the cell capture component includes a cell capture array having a plurality of cell capture micropillars, where the nucleic acid entanglement component includes a nucleic acid entanglement array having a plurality of nucleic acid entanglement micropillars, and where the microfluidic device operates under continuous flow conditions.

Abstract: An apparatus for forming an array of deposits on a substrate is disclosed. The apparatus may include a stencil capable of releasable attached to the substrate and having an array of openings and at least one alignment mark. The apparatus may further include a high throughput deposition printer aligned with the stencil to form an array of deposits on the substrate. The array of deposits may be aligned with the array of openings through the at least one alignment mark and an optional alignment device. Methods of manufacturing the stencil and using it to generate multiplexed or combinatorial arrays are also disclosed.

Abstract: An imbalance compensation system includes a receiver, a first path and a second path electrically coupled to the receiver, and a 90 degree hybrid coupler electrically connected to the second path, wherein the first path is configured to convey an in-phase (I) signal and the second path is configured to convey a quadrature phase (Q) signal. A processor is configured to perform Finite Impulse Response (FIR) filtering upon the I signal and the Q signal, wherein the processor is configured with an inverse matrix of coefficients corresponding to a frequency-dependent phase imbalance and a frequency-dependent amplitude imbalance between the I signal and the Q signal. The processor is configured to perform FIR filtering to attenuate an image signal down to a system noise floor when the processor simultaneously receives signals in a primary Nyquist region and a conjugate Nyquist region.

Abstract: A new approach for applying the multiple signal classification (MUSIC) method for high spectral resolution signal detection is described. The new approach uses a lower order covariance matrix, or, alternately, an autocorrelation matrix, to calculate only the number of eigenvalues and associated eigenvectors actually needed to solve for the number of signals sought.

Abstract: An apparatus for forming an array of deposits on a substrate is disclosed. The apparatus may include a stencil capable of releasable attached to the substrate and having an array of openings and at least one alignment mark. The apparatus may further include a high throughput deposition printer aligned with the stencil to form an array of deposits on the substrate. The array of deposits may be aligned with the array of openings through the at least one alignment mark and an optional alignment device. Methods of manufacturing the stencil and using it to generate multiplexed or combinatorial arrays are also disclosed.

Abstract: An array is formed with a protective cover on a substrate. The protective cover is patterned to produce an array of openings to the substrate. Desired material is deposited on the substrate through the openings. The protective cover may then be removed. In one embodiment, the protective cover is a conformal polymer, such as di-para-xylylene. It may be removed by mechanical peeling. The material may be biological material such as DNA. The protective cover may be used to prevent non-specific hybridization in inter-spot regions by performing hybridization with the cover still in place. Hybridization that occurs in such regions between the spots may be removed with removal of the protective cover.

Abstract: A moderate cost and complexity digital radio receiver system having enhanced instantaneous dynamic range response to the receipt of simultaneous signals and also providing large single signal dynamic range. Multiple signal instantaneous dynamic range improvement is achieved through use of a suppressed zero signal amplitude representation arrangement having a selected number of signal amplitude representing digital bits rather than the larger entire array of digital output bits of the receiver system's analog to digital converter. Digital apparatus for accomplishing the selection of desired high order bits from the analog to digital converter output is also disclosed in detail. Use of a “Monobit” and related simplified Fourier transformation radio receivers as disclosed in identified previous patents of the recited inventors and colleagues is preferred for embodying the digital radio receiver circuit included in a present system.

Abstract: A Fourier transformation algorithm implementation in which accommodation is provided for the output attenuation occurring when an input signal falls intermediate two terms of the transformation output series in its frequency. Corrected Fourier transformation terms, achieved by combining the magnitudes of attenuated Fourier transformation terms generated by the input signal at Fourier transformation frequencies distant to the input signal frequency, in either a vectorial or a scalar combination, are substituted for an attenuated Fourier transformation term according to the invention. Noise correction of the substitute Fourier transformation terms is also provided. The invention is disclosed through use of a global position system signal example that is subjected to a double Fourier transformation filtering process to enhance the incoming signal to noise ratio. Normally occurring 3.9 decibel attenuations in each Fourier transformation step are reduced to about 0.9 decibel each through use of the invention.

Abstract: A Fourier transformation arrangement usable in an electronic warfare radio receiver for analyzing spectral content of multiple transmitter-sourced brief duration incoming signals for their signal characteristics. The disclosed Fourier transformation arrangement includes approximated Kernel function values disposed in a significant plurality of locations about a real-imaginary coordinate axis origin according to disclosed locating principles. The points are displaced from the origin by magnitudes having real and imaginary component lengths of powers of two commencing with zero. Multiplication involving a power of two component length during a Kernel function utilization are preferably achieved by way of an expanded binary shift multiplication algorithm in lieu of a full fledged digital multiplication algorithm. A group of guiding principles for selecting desirable approximation Kernel function locations is included.

Abstract: A digital cueing radio receiver system embodied using digital memory in lieu of analog delay lines and thereby avoiding delay line implementation difficulties. The cueing receiver system includes a wideband receiver portion providing an output signal employed for tuning a narrowband receiver portion of the system. Signal delay enabling use of the wideband receiver portion output signals for tuning the narrow band receiver portion selection frequency is provided by a digital memory circuit operating on analog-to-digital converted samples of input signal data of the receiver system. Approximated unity value related mathematical multiplication free Kernel function values are employed in the Fourier transformation. Avoidance of analog delay line-elements in embodying the system is a significant practical advantage of the invention.

Abstract: A simplified, weak GPS C/A code coherent acquisition method. When performing GPS signal acquisition, the strength of a signal received at a GPS receiver having an outside antenna is generally sufficiently strong such that only 1 ms of data needs to be used in acquisition to find the signal. However, for weak signals received at a GPS receiver, when the antenna is inside a building or vehicle, for example, a long record of data is needed for acquisition. The present invention reduces the calculation burden for GPS signal acquisition for a weak signal.

Abstract: A global position system radio receiver achieved through use of an electronic warfare receiver, and particularly one of the electronic warfare receiver output frequency channels, as a front-end signal processor for the global position system receiver. Electronic warfare receiver channel selection for such usage is described and the attenuating effect of electronic warfare receiver channel center frequency and global position system signal frequency differences are considered. A favorable comparison of present invention and conventional global position system receiver-generated results in processing a global position system signal are included along with control of a sampling frequency characteristic within the electronic warfare receiver in order to align global position system signal frequency and electronic warfare receiver channel location to an electable better degree.

Abstract: An electronic warfare apparatus for determining the location of for example a ground based source of electromagnetic radiation from a platform such as an aircraft. Location is determined using angle of arrival based vector determinations provided by signal differences detected in the ground based signals arriving at platform antennas. Elimination of angle of arrival errors arising from imprecise knowledge of platform electronic warfare antenna characteristics is a focal point of the invention and is accomplished through precision use of global position system information received via the same electronic warfare antennas. Accurate determination of electronic warfare antenna characteristics prior to consideration of the large distance multiplication factors imposed by aircraft to distant signal source geometry enables accurate distant signal source location using the invention.

Abstract: An arrangement for calibrating the sample frequency determining clock in a global position system receiver using signals received from a Wide Area Augmentation System satellite or other Wide Area Augmentation System signal source. Such Wide Area Augmentation System based clock calibration is free of the Doppler frequency effects impressed on a global position system signal in view of the geo-stationary orbit of a Wide Area Augmentation System satellite. Use of the calibration invention enables correction of the pseudo range determination accomplished with global position system receiver output data. The invention may be considered a new use of signals available from the Wide Area Augmentation System. A noise-considered arrangement for comparing Wide Area Augmentation System and global position system frequencies is included.

Abstract: An improved apparatus and method for determining the carrier frequency in a biphase coded signal such as the course acquisition code signal in a global position sensing system. The described system may also be used for other purposes. The described system is based on use of the conventional data signal squaring or frequency doubling step to remove biphase coding but performs a series of frequency reducing steps prior to applying the Fourier transformation sequence. The frequency reducing steps include heterodyne mixing and signal averaging. These frequency-reducing steps diminish the speed and capacity requirements imposed on the Fourier transformation sequence and thereby decrease the cost and complexity of the overall system.