Patents by Inventor David M. Lokensgard

David M. Lokensgard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymer-based sustained release device
    Patent number: 9238076
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: January 19, 2016
    Assignees: Alkermes Pharma Ireland Limited, Amylin Pharmaceuticals, LLC
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David M. Lokensgard, Henry R. Costantino
  • Poly(lactide-co-glycolide) based sustained release microcapsules comprising a polypeptide and a sugar
    Patent number: 8293871
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: October 23, 2012
    Assignees: Alkernnes Pharma Ireland Limited, Amylin Pharmaceuticals, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino, Christine Smith, David M. Lokensgard, Mark Fineman, John Ong
  • Polymer-based sustained release device
    Publication number: 20080119569
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Application
    Filed: July 20, 2007
    Publication date: May 22, 2008
    Applicant: Alkermes, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David M. Lokensgard, Henry R. Costantino
  • Solvent extraction process
    Patent number: 5232707
    Abstract: There is disclosed a process for the extraction of volatile solvents entrained in a polymer-based pharmaceutical composition designed for sustained release of drug over an extended period of time prepared in microcapsule form wherein the composition comprises at least one hormonally active water-soluble polypeptide in an effective amount greater than a conventional single dose and a biocompatible, bioerodable encapsulating polymer, which process comprises the steps of contacting the composition to a stream of dense gas, that is, pressurized gas and then removing the dense gas, and volatile solvents contained therein, extracted from the pharmaceutical composition.
    Type: Grant
    Filed: September 13, 1991
    Date of Patent: August 3, 1993
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: David M. Lokensgard