Patents by Inventor David M. Lubman

David M. Lubman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110236993
    Abstract: The present invention relates to pancreatic cancer markers. In particular, the present invention provides methods and compositions for the identification of protein glycosylation patterns associated with pancreatic cancer.
    Type: Application
    Filed: September 9, 2009
    Publication date: September 29, 2011
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: David M. Lubman, Diane M. Simeone, Chen Li
  • Publication number: 20090136960
    Abstract: The present invention relates to methods and compositions for the identification of cancer markers. In particular, the present invention provides methods and compositions for the identification of glycosylated proteins and protein glycosylation patterns. The present invention further provides cancer markers identified using the described methods.
    Type: Application
    Filed: March 26, 2007
    Publication date: May 28, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: David M. Lubman, Diane M. Simeone, Jia Zhao
  • Publication number: 20090099036
    Abstract: The present invention relates to methods and compositions for screening of glycan structures. In particular, the present invention provides methods and compositions for global profiling of glycoprotein states by utilizing a glycoprotein microarray format. The present invention further provides for methods and compositions of glycoprotein microarray formats for differentiating between different glycosylation states associated with disease states.
    Type: Application
    Filed: April 18, 2007
    Publication date: April 16, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: David M. Lubman, Tasneem H. Patwa, Jia Zhao
  • Publication number: 20080280771
    Abstract: The present invention relates to automated methods, systems, and apparatuses for protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of the phosphorylation status of protein samples, including the generation and analysis of protein microarrays.
    Type: Application
    Filed: June 19, 2007
    Publication date: November 13, 2008
    Applicant: Regents of the University of Michigan
    Inventors: David M. Lubman, Arul M. Chinnaiyan, Manoj Pal, Arun Sreekumar, Stephen P. Ethier
  • Publication number: 20080153711
    Abstract: The present invention relates to automated methods, systems, and apparatuses for protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the separation and analysis of samples containing a plurality of proteins (e.g., cells).
    Type: Application
    Filed: June 20, 2007
    Publication date: June 26, 2008
    Applicant: Regents of the University of Michigan
    Inventors: David M. Lubman, Arul M. Chinnaiyan, Manoj Pal, Arun Sreekumar, Stephen P. Ethier
  • Patent number: 7069151
    Abstract: The present invention relates to protein separation systems and methods capable of resolving and characterizing large numbers of cellular proteins. In particular, the present invention provides a novel mass mapping system and methods for the differential display of proteins. The present invention further provides novel methods for displaying differential protein expression between two samples. In particular, the present invention provides novel method of mapping differential expression of proteins in non-cancerous, pre-cancerous, and cancerous cells.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: June 27, 2006
    Assignee: Regents of the University of Michigan
    Inventors: David M. Lubman, Bathsheba E. Chong, Stephen J. Parus
  • Patent number: 6931325
    Abstract: The present invention relates to multi-phase protein separation methods capable of resolving and characterizing large numbers of cellular proteins, including methods for efficiently facilitating the transfer of protein samples between separation phases. In particular, the present invention provides systems and methods for the generation of multi-dimensional protein maps. The present invention thus provides improved methods for the analysis of samples containing large numbers of proteins.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: August 16, 2005
    Assignee: Regents of the University of Michigan
    Inventors: Daniel B. Wall, David M. Lubman, Timothy Barder
  • Publication number: 20040214233
    Abstract: The present invention relates to automated methods, systems, and apparatuses for protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the separation and analysis of samples containing a plurality of proteins (e.g., cells).
    Type: Application
    Filed: January 13, 2004
    Publication date: October 28, 2004
    Applicant: The Regents of the University of Michigan
    Inventors: David M. Lubman, Arul M. Chinnaiyan, Arun Sreekumar, Bharathi Laxman, Fang Yan
  • Publication number: 20040033591
    Abstract: The present invention relates to automated methods, systems, and apparatuses for protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the separation and analysis of samples containing a plurality of proteins (e.g., cells).
    Type: Application
    Filed: May 30, 2003
    Publication date: February 19, 2004
    Applicant: The Regents of the University of Michigan
    Inventors: David M. Lubman, Stephen J. Parus, Chul S. Yoo
  • Publication number: 20040010126
    Abstract: The present invention relates to multiphase protein separation methods capable of resolving large numbers of cellular proteins. The methods of the present invention provide protein profile maps for imaging and comparing protein expression patterns. The present invention provides alternatives to traditional 2-D gel separation methods for the screening of protein profiles.
    Type: Application
    Filed: October 1, 2001
    Publication date: January 15, 2004
    Applicant: The Regents of the University of Michigan
    Inventors: David M. Lubman, Timothy J. Barder, Daniel B. Wall, Stephen J. Parus, Maureen T. Kachman, Bathsheba E. Chong, Samir M. Hanash, David E. Misek, Robert Hinderer
  • Publication number: 20030064527
    Abstract: The present invention relates to multi-phase protein separation methods capable of resolving and characterizing large numbers of cellular proteins, including methods for efficiently facilitating the transfer of protein samples between separation phases. In particular, the present invention provides systems and methods for the differential display of protein samples from multiple cell types. The present invention thus provides improved methods for the analysis of multiple samples containing large numbers of proteins.
    Type: Application
    Filed: April 26, 2002
    Publication date: April 3, 2003
    Applicant: The Regents of the University of Michigan
    Inventors: David M. Lubman, Maureen Kachman, Stephen J. Parus
  • Publication number: 20030058239
    Abstract: The present invention relates to multi-phase protein separation methods capable of resolving and characterizing large numbers of cellular proteins, including methods for efficiently facilitating the transfer of protein samples between separation phases. In particular, the present invention provides systems and methods for the generation of multi-dimensional protein maps. The present invention thus provides improved methods for the analysis of samples containing large numbers of proteins.
    Type: Application
    Filed: April 26, 2002
    Publication date: March 27, 2003
    Applicant: The Regents of the University of Michigan
    Inventors: Daniel B. Wall, David M. Lubman, Tiimothy Barder
  • Publication number: 20020098595
    Abstract: The present invention relates to multi-phase protein separation methods capable of resolving and characterizing large numbers of cellular proteins, including methods for efficiently facilitating the transfer of protein samples between separation phases. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the analysis of samples containing large numbers of proteins.
    Type: Application
    Filed: February 7, 2001
    Publication date: July 25, 2002
    Applicant: The Regents of the University of Michigan
    Inventors: David M. Lubman, Timothy J. Barder, Daniel B. Wall, Stephen J. Parus, Maureen T. Kachman, Bathsheba E. Chong, Robert C. North, Fang Yan
  • Publication number: 20020039747
    Abstract: The present invention relates to protein separation systems and methods capable of resolving and characterizing large numbers of cellular proteins. In particular, the present invention provides a novel mass mapping system and methods for the differential display of proteins. The present invention further provides novel methods for displaying differential protein expression between two samples. In particular, the present invention provides novel method of mapping differential expression of proteins in non-cancerous, pre-cancerous, and cancerous cells.
    Type: Application
    Filed: February 7, 2001
    Publication date: April 4, 2002
    Applicant: The Regents of the University of Michigan
    Inventors: David M. Lubman, Bathsheba E. Chong, Stephen J. Parus