Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.

Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.

Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.

Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.

Abstract: A pen-injector device comprising an anti-IL-6 antibody with a liquid formulation have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: A pen-injector device comprising an anti-IL-6 antibody with a liquid formulation have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.

Abstract: The present invention relates to CD20 binding molecules and nucleic acid sequences encoding CD20 binding molecules. In particular, the present invention relates to CD20 binding molecules with a high binding affinity, and a low dissociation rate, with regard to human CD20. Preferably, the CD20 binding molecules of the present invention comprise light and/or heavy chain variable regions with fully human frameworks (e.g. human germline frameworks).

Abstract: The present invention provides domain 1 ?2GPI polypeptides, polynucleotides encoding these polypeptides, mimetics of these polypeptides, and methods using domain 1 ?2GPI polypeptides and mimetics. Domain 1 of ?2GPI has been shown to bind to anti-cardiolipin (?2GPI-dependent antiphospholipid) antibodies, which are associated with several pathologies, such as thrombosis and fetal loss. The domain 1 ?2GPI polypeptides may be used to detect ?2GPI-dependent antiphospholipid antibodies in a sample. The invention further provides methods of inducing tolerance using these domain 1 ?2GPI polypeptides.

Abstract: A method for enhancing the recovery of petroleum from an oil bearing formation during injection of a non-condensible gas comprises the at least periodic injection of a foam forming composition or a preformed foam into the reservoir. The foam which is produced comprises a mixture of a non-condensible gas, water and a non-ionic surfactant. The non-ionic surfactants which can be employed in the present invention are those non-ionic surfactants which have a HLB value of about 14 to less than 20, preferably 15-18, and which provide a stable foam when the surfactant is mixed with brine and/or water and a non-condensible gas. The method is preferably employed within a light oil bearing carbonate formation.

Abstract: A method for enhancing the recovery of petroleum from an oil bearing formation during injection of a non-condensible gas comprises the at least periodic injection of a foam forming composition or a preformed foam into the reservoir. The foam comprises a mixture of a non-condensible gas, preferably CO.sub.2, water and an alpha-olefin sulfonate. The alpha-olefin sulfonate comprises a mixture of hydroxy-sulfonates and alkene-sulfonates wherein the ratio of alkene-sulfonates to hydroxy-sulfonates is preferably not greater than about 4. In addition, the hydroxy-sulfonates comprises 3-hydroxy and 4-hydroxy-sulfonates wherein the ratio of 3-hydroxy-sulfonates to 4-hydroxy-sulfonates is at least about 2. The method is preferably employed within a light oil bearing formation comprising sandstone.

Abstract: A process for the preparation of 2,6-dialkylaniline which comprises the reaction of 1,3-dialkylbenzene with isobutene in the presence of a hydrogen fluoride catalyst to form 1,3-dialkyl-5-tertiary-butylbenzene, which is subsequently nitrated in the presence of a soluble mercuric salt catalyst to form 2-nitro-1,3-dialkyl-5-tertiary-butylbenzene, which is then catalytically hydrogenated to give 2,6-dialkyl-4-tertiary-butylaniline, followed by pyrolysis in the presence of a heterogeneous acidic catalyst.

Abstract: A process for producing maleic anhydride from a C.sub.4 hydrocarbon selected from n-butane and n-butene feed which comprises: (a) feeding the C.sub.4 hydrocarbon and air to a reactor; (b) contacting the C.sub.4 hydrocarbon and air in the reactor with a catalyst comprising vanadium and phosphorus oxides at reaction conditions including a temperature between 550.degree. and 1000.degree. F. so as to obtain a reactor effluent containing maleic anhydride, unreacted butane, nitrogen, oxygen, and acrylic, acetic or maleic acid or mixtures of the foregoing acids; (c) removing maleic anhydride from the reactor effluent to obtain maleic anhydride-lean effluent; (d) removing said acids from at least a portion of the maleic anhydride-lean effluent to obtain a purified recycle stream containing less than 100 ppm of the acids; and (e) recycling the purified stream to the reactor. Preferably the acids are removed in step (d) by water and/or caustic scrubbing the maleic anhydride-lean effluent.

Abstract: A process for producing maleic anhydride from n-butane which comprises:(a) feeding n-butane and air to a reactor;(b) contacting the butane and air with a catalyst comprising vanadium and phosphorus oxides at reaction conditions including a temperature between 550.degree. F. and 1000.degree. F. so as to convert 15 to 28% of the butane per pass and obtain a reactor effluent containing maleic anhydride, unreacted butane, nitrogen, and oxygen;(c) removing maleic anhydride from the reactor effluent to obtain maleic anhydride-lean effluent;(d) recycling a portion of the maleic anhydride-lean effluent to the reactor;(e) removing butane from the other portion of the maleic anhydride-lean effluent; and(f) recycling the removed butane to the reactor.Preferably the temperature in, and/or space velocity through, the reactor is adjusted to obtain a weight percent selectivity to maleic anhydride of at least 90% of the butane converted.

Abstract: A crystalline vanadium (IV) phosphate composition having an intrinsic surface area in excess of 10 square meters per gram is prepared by the reaction of orthophosphoric acid with a vanadium (IV) oxycompound. The vanadium compound is suspended in a suitable hydroxylic organic medium, for example isobutanol, and contacted with the acid at a temperature in the range 20.degree. C. to 210.degree. C. until the conversion is completed. The catalyst is used in the oxidation of n-butane to maleic anhydride.

Abstract: A crystalline vanadium (IV) phosphate composition having an intrinsic surface area in excess of 10 square meters per gram is prepared by the reaction of orthophosphoric acid with a vanadium (IV) oxycompound. The vanadium compound is suspended in a suitable hydroxylic organic medium, for example isobutanol, and contacted with the acid at a temperature in the range 20.degree. C. to 210.degree. C. until the conversion is completed.

Abstract: An absorption process for separating a maleic or phthalic anhydride from a gaseous mixture containing the anhydride which comprises contacting the gaseous mixture with a liquid absorbent comprising polymethylbenzophenones, at least a portion of which benzophenones contain at least 3 methyl groups, at a temperature for the absorbent between about 20.degree. and 235.degree. C and at a pressure sufficient to effect absorption of the anhydride into the absorbent. Preferably the absorption process is used to remove maleic anhydride from a gas stream, preferably the absorbent includes dixylylketone, and preferably the absorption is carried out by countercurrent contacting in an absorber column.