Abstract: An adapter for releasably attaching a syringe to an injector. The adapter comprises a mounting mechanism positioned at a rear end of the adapter to mount the adapter in a desired position relative to a front wall of the injector; and a syringe carrier section adapted to seat at least a portion of the syringe. The syringe carrier section defines a first opening on a top thereof to allow placement of the syringe therein from the top and a second opening in a rear section thereof to allow the drive member of the injector to communicate forward force to the plunger. A cover portion extends over a rearward end of the first opening and has a first end configured to abut the flange of the syringe when the syringe is positioned within the syringe carrier section.

Abstract: An implantable heart assist system includes a compressible pumping chamber including an inlet conduit to be placed in fluid connection with the descending thoracic aorta and an outlet conduit to be placed in fluid connection with the thoracic aorta; and a pump system comprising a first rigid member, a second rigid member positioned so that at least a portion of the pumping chamber may be positioned between the first and second rigid members, a drive system configured to cause the second rigid member to move toward or away from the first rigid member, and a controller in operative connection with the drive system and controlling the drive system, wherein movement of the second rigid member toward the first rigid member results in compresses the pumping chamber and movement of the second rigid member away from the first rigid member expands the pumping chamber.

Abstract: A fluid connector includes an extending section having a spiked end to pierce a container port. The extending section includes at least one air conduit and at least one fluid conduit therethrough. The extending section further includes first and second abutment members. The first abutment member is adapted to abut a first or air side of the container port upon piercing of the container port, and the second abutment member, which is spaced from the first abutment member, is adapted to abut a second or fluid side of the container port. The fluid connector can further include grasping members extending from the extending section to facilitate rotation of the extending section relative to the container port during piercing thereof. The fluid connector can also include a check valve in fluid connection with the at least one air conduit. The check valve may be positioned within the extending section.

Abstract: An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.

Abstract: A system for delivering to a patient a slurry which includes a fluid and a material that is non-dissolvable or immiscible in the fluid. The system includes a container adapted to contain the slurry and a supernate of the slurry, a syringe adapted to contain the slurry after dilation with the supermate, a fluid path between the syringe and the contents of the container, the fluid path including a needle at least partially disposed within the contents of the container, a plunger disposed in the syringe and adapted to create pressure in the syringe to cause a dilated slurry to flow into the syringe through the fluid path, and a fluidizing systen associated with the container and comprising a holder adapted to move the needle within the container to affect dilation of the slurry with a portion of the supernate.

Abstract: A fluid path set including a multi-patient use section adapted for connection with a pump device and a source of injection fluid, and a per-patient use section adapted for removable fluid communication with the multi-patient use section. The per-patient use section includes a pressure isolation mechanism having a first port adapted for connection to the pump device via the multi-patient use section, a second port adapted for connection to a patient, and a pressure isolation port adapted for connection to a source of medical fluid via the multi-patient use section. The per-patient use section includes a valve member biased to a normally open position permitting fluid communication between the first port, the second port, and the pressure isolation port, and movable to a closed position to close the pressure isolation port when fluid pressure reaches a predetermined pressure level sufficient to overcome a biasing force applied to the valve member.

Abstract: An implantable heart assist system, includes a pumping chamber formed of a flexible material and being adapted to be placed in fluid connection with the aorta and a pump system comprising a first rigid member and a spaced apart second rigid member so that at least a portion of the pumping chamber may be positioned therebetween, a drive system comprising a motor. The motor is adapted to cause the second rigid member to move toward the first rigid member to compress the pumping chamber or away from the first rigid member to expand the pumping chamber. A controller is in operative connection with the drive system and controlling the motor.

Abstract: A catheter including an outer conduit and an inner conduit positioned within the outer conduit, the inner conduit having a smaller diameter that that of the outer conduit. A volume between the outer conduit and the inner conduit define a first lumen which may deliver a first fluid to a patient, and an inside diameter of the inner conduit defines a second lumen which may deliver a second fluid to the patient such that the fluid flow of the first fluid and the second fluid exiting the catheter has a flow profile where the first fluid surrounds the second fluid and the second fluid is prevented from contact with inner walls of a blood vessel of the patient in a vicinity of a tip of the catheter.

Abstract: A system for delivery of a medical fluid to a patient includes a pump system including a pressurizing unit to pressurize the medical fluid and a drive system in operative connection with the pressurizing unit. The pump system exhibits variation in pressure during operation. The system further includes a compensating system in fluid connection with the medical fluid pressurized by the pressurizing unit. The compensating system defines a displacement volume in fluid connection with the pressurized medical fluid that is altered in a predetermined manner to alter the variation in pressure. The compensating system can, for example, reduce pulsatility of pressure during flow.

Abstract: A fluid connector includes an extending section including a spiked end to pierce the container port. The extending section includes at least one air conduit and at least one fluid conduit therethrough. The extending section further includes a first abutment member and second abutment member. The first abutment member is adapted to abut a first or air side of the container port upon piercing of the container port. The second abutment member is spaced from the first abutment member and is adapted to abut a second or fluid sided of the container port. The fluid connector can further include grasping members extending from the extending section to facilitate rotation of the extending section relative to the container port during piercing thereof. The fluid connector can also include a check valve in fluid connection with the air line. In several embodiments, the check valve is positioned within the extending section.

Abstract: A system for assisting blood flow in a patient includes an implantable pump system for assisting in blood flow from the heart and an implantable control system for communicative connection with the implantable pump system. The control system includes a pacemaker system that is operative to control heart rate and the pump system interdependently to achieve a determined level of blood flow assist. The control system is adapted to increase the heart rate of the patient to above a normal heart rate for the patient under the present conditions of the patient via the pacemaker while controlling the pump system to achieve the determined level of blood flow assist based upon the increased heart rate and a level of assist provided by the pump system.

Abstract: A medical connector for delivering a liquid at a high flow rate to a patient. The connector includes a gas inlet passage that is configured for connecting to a source of pressurized gas, a spike configured for piercing a stopper of a container, and a liquid outlet passage in fluid communication with the spike. The liquid outlet passage is configured for connecting to tubing through which the liquid in the container can be administered to a patient. The spike has a shield having a first closed end and a second open end such that the first closed end is breakable by the spike when the spike is inserted through the stopper of the container, and the second open end has an annular elastomeric member that attaches to the spike via compressive pressure applied by the annular elastomeric member.

Abstract: A hazardous fluid handling system which includes a housing having a radiation shielded internal chamber disposed therein which may accommodate a container holding a radioactive fluid, one or more radioactivity detectors positioned within the shielded internal chamber in operational proximity to the radioactive fluid in the container, and a dosimeter control device electronically coupled to the radioactivity detector(s) is disclosed. The dosimeter control device is operational for determining information regarding the radioactive fluid in the container based on individual measurements received from the one or more radioactivity detectors. The hazardous fluid handling system may be integrated into a patient support platform which includes a patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with the patient, and an integrated system controller.

Abstract: A fluid delivery system includes a fluid container, two or more pressurizing chambers in fluid connection with the fluid container, a drive mechanism in operative connection with the two or more pressurizing chambers to pump fluid from the fluid container and an outlet in fluid connection with the two or more pressurizing chambers. Each of the two or more pressurizing chambers is formed from a flexible, resilient material that is adapted to be compressed to pressurize fluid therewithin.

Abstract: A fluid mixing system including an extending channel, at least two fluid inlet ports in fluid connection with the extending channel, at least one outlet port in fluid connection with the extending position between the two fluid inlet ports and a sealing member in sealing engagement with the extending channel is described. The sealing member may be movable within the extending channel to adjust the volumetric ratio of the two fluids delivered through the outlet port.

Abstract: A system for delivering fluid to a patient includes a hazardous material enclosure suitable for holding a first container comprising a first fluid, and a pump device capable of pumping the first fluid from the first container and a second fluid from a second container. The hazardous materials enclosure has a cap which includes a flexible sealing member that cooperates with the first container to create a biohazard seal during connection of the first container to the cap. The system further includes a mixing device associated with the pump for mixing the first and second fluids for delivering the fluid mixture to the patient.

Abstract: A system for delivery of medical fluid to a patient which includes a pump system and a drive system. The pump system has at least three chambers, where each chamber includes an inlet for fluid intake and an outlet for fluid expulsion, a common outlet channel in fluid communication with the outlet of each chamber, and at least three pistons, where each piston is slidably disposed within one of the chambers. The drive system includes a cam shaft having at least three cam lobes, each having a profile, and at least three cam lobe followers, each in operative connection with one of the cam lobes and adapted to be placed in operative connection with a respective piston. The profile of each of the cam lobes is adapted to provide a transient increase or spike in calculated theoretical output of the pump system to reduce periodic variation in measured output thereof.

Abstract: In one aspect, an implantable pump system for assisting blood flow in a patient includes a blood flow path comprising a flexible conduit, at least one valve in fluid connection with the flexible conduit, a drive system in operative connection with the valve to move the valve in a reciprocating manner, an implantable control system and at least one sensor in communicative connection with the control system. The sensor is adapted to measure at least one property of blood. The control system is adapted to control movement of the valve on the basis of data regarding position of the valve with respect to time or a derivative thereof (that is, position, velocity, acceleration or a derivative thereof) in combination with data of the measured at least one property of blood from the sensor.

Abstract: An injector system includes a powered injector, a pressurizing chamber in operative connection with the powered injection, a fluid path in fluid communication with the pressurizing chamber, and a manual control in fluid connection with the fluid path. The manual control includes at least one actuator for controlling the injector through application of force by an operator. The actuator provides tactile feedback of pressure in the fluid path to the operator via a fluid connection therewith. An injection system for use in angiography includes a source of saline, a pump in fluid connection with the source of saline to pressurized the saline, a source of contrast, a contrast valve in fluid connection with the source of contrast, a powered injector in fluid connection with the contrast valve, and a pressure isolation mechanism.

Abstract: A system and method for mixing and delivering fluids such as contrast media and saline is disclosed including at least two fluid sources, a pump, a joining fluid path for connecting the at least two fluid sources to an inlet to of the pump, and a valve device in the fluid path upstream of the pump. The valve device includes an actuator adapted to restrict flow in at least one of the respective fluid lines connecting the at least two fluid sources to the pump inlet. A patient interface device may be associated with an outlet of the pump. The valve device actuator is generally adapted to restrict the flow in at least one of the respective fluid lines such that a positional change in valve device actuator position provides a change in fluid mixture ratio of the fluids from the at least two fluid sources to the pump inlet.