Patents by Inventor David M. Roof

David M. Roof has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Double motor mutant assay for antifungal agents
    Patent number: 6905840
    Abstract: Provided are methods of identifying potential antifungal agents, and particularly those having antimitotic activity. Fungal cells having double mutations which alter microtubule stability and inhibit cell proliferation are used in the methods. Test compounds are screened to identify those which are able to promote cell proliferation o the mutant fungal cells and counteract the stabilizing effect of the double mutations on the microtubules. High-throughput methods of selecting for the novel antifungal agents are also provided.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: June 14, 2005
    Assignee: Cytokinetics, Inc.
    Inventors: David M. Roof, Mary Maxon