Patents by Inventor David M. Schubert
David M. Schubert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11970479Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.Type: GrantFiled: October 24, 2019Date of Patent: April 30, 2024Assignees: Merck Sharp & Dohme LLC, MSD R&D (China) Co. LTD.Inventors: John J. Acton, III, Melissa Egbertson, Xiaolei Gao, Scott T. Harrison, Timothy J. Henderson, Michael Man-Chu Lo, Robert D. Mazzola, Jr., Zhaoyang Meng, James Mulhearn, Vanessa L. Rada, Jeffrey W. Schubert, Oleg B. Selyutin, David M. Tellers, Ling Tong, Fengqi Zhang, Jianming Bao, Chunsing Li
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Patent number: 8308997Abstract: The invention relates to a fire resistant composition and a method of making fire resistant cellulosic materials comprising the fire resistant composition. More specifically, the invention relates to liquid compositions, including liquid compositions comprising urea and a boron -containing compound for imparting fire resistance to cellulosic products. The boron-containing compound typically comprises boric acids; borates (i.e., boric acid salts); boric oxides (i.e., any compound containing boron and oxygen), and mixtures thereof.Type: GrantFiled: December 17, 2008Date of Patent: November 13, 2012Assignee: U.S. Borax Inc.Inventor: David M. Schubert
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Publication number: 20090156073Abstract: The invention relates to a fire resistant composition and a method of making fire resistant cellulosic materials comprising the fire resistant composition. More specifically, the invention relates to liquid compositions, including liquid compositions comprising urea and a boron-containing compound for imparting fire resistance to cellulosic products. The boron-containing compound typically comprises boric acids; borates (i.e., boric acid salts); boric oxides (i.e., any compound containing boron and oxygen), and mixtures thereof.Type: ApplicationFiled: December 17, 2008Publication date: June 18, 2009Inventor: David M. Schubert
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Patent number: 7547354Abstract: Compositions and methods are provided for treating wood products to provide leach-resistant protection against fungal decay, termites and other wood destroying organisms. The preservative compositions provided include ammonia-stabilized solutions of zinc and boron, preferably in a molar ratio of Zn:B of between about 0.4:1 and 5:1, and are essentially copper free. The preservative may be applied by vacuum and/or pressure treatment or dip treatment under atmospheric pressure.Type: GrantFiled: March 31, 2005Date of Patent: June 16, 2009Assignees: PQ Corporation, U.S. Borax Inc.Inventors: Yatao Hu, Neil T. Miller, David M. Schubert
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Patent number: 7497900Abstract: Systems and methods are provided for treating products containing wood fibers to provide protection against wood destroying organisms and fire, and resistance against leaching of the preservative from the wood by water in exposed environments such as exterior applications. The methods involve applying to a substrate a first aqueous composition containing a boron compound, a source of zinc, and ammonia, followed by application of a second aqueous composition containing an alkali metal silicate. The compositions may be applied by vacuum and/or pressure treatment or dip treatment under atmospheric pressure.Type: GrantFiled: March 31, 2005Date of Patent: March 3, 2009Assignees: PQ Corporation, U.S. Borax Inc.Inventors: Yatao Hu, Jason D. Lenox, Neil T. Miller, David M. Schubert
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Publication number: 20080305351Abstract: A method for inhibiting the crystallization of boric acid is provided. Boric acid is dissolved in water and a vitrifying agent, such as an amino alcohol or amino acid, to form an aqueous mixture which is then dried to form a vitreous boric acid-containing residue. This mixture, when applied to a surface and allowed to dry on the surface, forms a vitreous boric acid-containing coating which is readily adherent to the surface, or if allowed to penetrate into a porous substrate, deposits a vitreous boric acid-containing residue within the substrate upon drying. The vitreous boric acid-containing residue provides beneficial properties, including for example improved fire retardancy and biocidal protection, to a variety of materials such as cotton batting, cellulose, and wood and paper products and gypsum wallboard.Type: ApplicationFiled: March 24, 2005Publication date: December 11, 2008Inventor: David M. Schubert
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Publication number: 20080166481Abstract: Compositions and methods are provided for treating wood products to provide leachresistant protection against fungal decay, termites and other wood destroying organisms. The preservative compositions provided include ammonia-stabilized solutions of zinc and boron, preferably in a molar ratio of Zn:B of between about 0.4:1 and 5:1, and are essentially copper free. The preservative may be applied by vacuum and/or pressure treatment or dip treatment under atmospheric pressure.Type: ApplicationFiled: March 31, 2005Publication date: July 10, 2008Inventors: Yatao Hu, Neil T. Miller, David M. Schubert
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Publication number: 20080124478Abstract: Systems and methods are provided for treating products containing wood fibers to provide protection against wood destroying organisms and fire, and resistance against leaching of the preservative from the wood by water in exposed environments such as exterior applications. The methods involve applying to a substrate a first aqueous composition containing a boron compound, a source of zinc, and ammonia, followed by application of a second aqueous composition containing an alkali metal silicate. The compositions may be applied by vacuum and/or pressure treatment or dip treatment under atmospheric pressure.Type: ApplicationFiled: March 31, 2005Publication date: May 29, 2008Applicants: U.S. BORAX INC., PQ CORPORATIONInventors: Yatao Hu, Jason D. Lenox, Neil T. Miller, David M. Schubert
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Patent number: 6919036Abstract: A family of borate compounds containing an isolated (finite) nonaborate anion with the structural formula [B9O12(OH)6]3?. Preferred amine nonaborate compounds have a resolved oxide formula of A2O.3B2O3.2H2O, where A is the monovalent cation of an amine salt, such as guanidinium and imidazolium. Also provided is a method for preparing these compounds by crystallization from an aqueous solution under mild conditions without the formation of significant amounts of by-products. These compounds have potential application as precursors for the production of advanced boron nitride ceramic materials, and as flame retardants, corrosion inhibitors, and biocides.Type: GrantFiled: January 18, 2001Date of Patent: July 19, 2005Assignee: U.S. Borax Inc.Inventor: David M. Schubert
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Publication number: 20030109751Abstract: A family of borate compounds containing an isolated (finite) nonaborate anion with the structural formula [B9O12(OH)6]3−. Preferred amine nonaborate compounds have a resolved oxide formula of A2O.3B2O3.2H2O, where A is the monovalent cation of an amine salt, such as guanidinium and imidazolium. Also provided is a method for preparing these compounds by crystallization from an aqueous solution under mild conditions without the formation of significant amounts of by-products. These compounds have potential application as precursors for the production of advanced boron nitride ceramic materials, and as flame retardants, corrosion inhibitors, and biocides.Type: ApplicationFiled: July 19, 2002Publication date: June 12, 2003Inventor: David M Schubert
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Patent number: 5785939Abstract: An improved method is provided for producing crystalline calcium hexaborate tetrahydrate, synthetic nobleite, by the reaction of boric acid and lime in an aqueous slurry. Reaction conditions include boric acid to water molar ratios of greater than 0.25:1, lime to boric acid molar ratios in the range of 0.05-0.15:1 and temperatures in the range of 60.degree.-85.degree. C. A concentration of at least 25% by weight undissolved solids is in the aqueous product slurry.Type: GrantFiled: April 18, 1997Date of Patent: July 28, 1998Assignee: U.S. Borax Inc.Inventor: David M. Schubert
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Patent number: 5688481Abstract: An improved method is provided for producing crystalline calcium hexaborate tetrahydrate, synthetic nobleite, by the reaction of boric acid and lime in an aqueous slurry. Reaction conditions include boric acid to water molar ratios of greater than 0.25:1, lime to boric acid molar ratios in the range of 0.05-0.15:1 and temperatures in the range of 85.degree.-105.degree. C. A novel crystalline product is produced having a unique crystal habit resulting in improved physical properties. Dehydration of this product produced a novel amorphous, anhydrous product having similar crystal habit and physical properties.Type: GrantFiled: October 18, 1995Date of Patent: November 18, 1997Assignee: U.S. Borax Inc.Inventor: David M. Schubert
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Patent number: 5612094Abstract: Lumber, plywood and other wood products are preserved from attack by fungi, termites and wood-destroying insects as well as fire and flame by treatment with a novel zirconium borate-containing preservative composition. The preservative can be formed by combination of a source of boron such as boric acid and the water-soluble salts thereof with a water-soluble zirconium salt. The ZrO.sub.2 :B.sub.2 O.sub.3 weight ratio in the preservative composition is in the range of from about 0.75:1 to about 10:1.Type: GrantFiled: October 18, 1995Date of Patent: March 18, 1997Assignee: U.S. Borax Inc.Inventors: David M. Schubert, Mark J. Manning
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Patent number: 5472644Abstract: Zinc borate compositions having a ZnO:B.sub.2 O.sub.3 ratio of 4:1. The hydrated zinc borate 4ZnO.B.sub.2 O.sub.3.H.sub.2 O and anhydrous zinc borate 4ZnO.B.sub.2 O.sub.3 are especially useful as fire-retardants and smoke-suppressant additives for polymeric compositions.Type: GrantFiled: June 10, 1994Date of Patent: December 5, 1995Assignee: U.S. Borax Inc.Inventor: David M. Schubert
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Patent number: 5342553Abstract: Zinc borate compositions having a ZnO:B.sub.2 O.sub.3 ratio of 4:1. The hydrated zinc borate 4ZnO.B.sub.2 O.sub.3.H.sub.2 O and anhydrous zinc borate 4ZnO.B.sub.2 O.sub.3 are especially useful as fire-retardants and smoke-suppressant additives for polymeric compositions.Type: GrantFiled: November 22, 1991Date of Patent: August 30, 1994Assignee: U. S. Borax Inc.Inventor: David M. Schubert