Patents by Inventor David M. Shechner

David M. Shechner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of making and using guide RNA for use with Cas9 systems
    Patent number: 10920221
    Abstract: CRISPR/Cas Systems are provided where guide RNAs include one or more selected RNA sequences for delivery to a target nucleic acid sequence.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: February 16, 2021
    Assignee: President and Fellows of Harvard College
    Inventors: John L. Rinn, David M. Shechner
  • Methods of Making and Using Guide RNA for Use With Cas9 Systems
    Publication number: 20190106693
    Abstract: CRISPR/Cas Systems are provided where guide RNAs include one or more selected RNA sequences for delivery to a target nucleic acid sequence.
    Type: Application
    Filed: May 13, 2016
    Publication date: April 11, 2019
    Applicant: President and Fellows of Harvard College
    Inventors: John L. Rinn, David M. Shechner
  • METHODS FOR ISOLATING ENDOGENOUS NUCLEIC ACIDS FROM SUBCELLULAR COMPARTMENTS WITHOUT FRACTIONATION
    Publication number: 20170227531
    Abstract: Methods of determining subcellular localization of nucleic acids, including RNA and DNA are described. In particular, the invention relates to a method combining proximity-specific labeling with crosslinking of nucleic acids to proteins and sequencing to identify nucleic acids within or near a particular subcellular compartment in vivo.
    Type: Application
    Filed: February 4, 2017
    Publication date: August 10, 2017
    Inventors: Alice Ting, Pornchai Kaewsapsak, David M. Shechner, John L. Rinn