Abstract: Disclosed is a valve assembly, having: a valve duct having an upstream end, a downstream end and a duct wall extending from the upstream end to the downstream end; a first conduit extending from a first end at the valve duct to a second end spaced apart from the first end, the first conduit terminating at a valve assembly component; and a washing filter that includes filer media, wherein the filter media extends into the valve duct to remove particles and provide a clean flow to the first conduit.

Abstract: A pressure actuated switching valve includes a first valve chamber including a first chamber portion. The first chamber portion has a first inner diameter, a second chamber portion having a second inner diameter that is greater than the first inner diameter, a third chamber portion having a third inner diameter that is greater than the first inner diameter, a fourth chamber portion having a fourth inner diameter that is greater than first inner diameter, and a valve member. The valve member includes a first section having a first outer diameter that is greater than the first inner diameter. A second section of the valve member has a second outer diameter that is closely matched to the third inner diameter. A third section of the valve member is arranged has a third outer diameter that is greater than the first outer diameter.

Abstract: Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.

Abstract: Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.

Abstract: Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.

Abstract: Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.

Abstract: Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.

Abstract: A turnstile locking system comprises: a first member which includes a face, two flanges attached perpendicularly to opposite edges of the face, and an aperture on each flange; a second member which includes a v-shaped face, two flanges attached to the v-shaped face, and an aperture on each flange; and a pin which includes a head and an aperture. The first member face may be flat or may include a triangular projection. The first and second members may be connected by one or more hinges. The locking system may further include a lock component, or any suitable lock such as a padlock may be used with the present invention. A turnstile locking method comprises: providing a turnstile locking system of the present invention; positioning the first and second members onto a turnstile; engaging the first and second members; inserting a pin through the flanges' apertures; inserting a lock component through the pin's aperture, and locking the lock component.

Abstract: The present invention provides a polymer blend suitable for use as a film or a coating, the polymer blend including from 1 to 99% by weight of a metallocene-produced VLDPE polymer having a density less than 0.916 g/cm3, and from 1 to 99% by weight of an LDPE polymer having a density of from 0.916 to 0.928 g/cm3 wherein the sum of (a) and (b) is 100%. The VLDPE polymer can have a melt index of from 6 to 15 dg/min, or from 9 to 12 dg/min.

Abstract: Catalytic antibodies are disclosed. The catalytic antibodies are specific for prodrug compounds. The catalytic antibodies enhance cleavage of an active drug moiety from a prodrug residue, thereby activating the drug.

Abstract: The present invention provides a polymer blend suitable for use as a film or a coating, the polymer blend including from 1 to 99% by weight of a metallocene-produced VLDPE polymer having a density less than 0.916 g/cm3, and from 1 to 99% by weight of an LDPE polymer having a density of from 0.916 to 0.928 g/cm3 wherein the sum of (a) and (b) is 100%. The VLDPE polymer can have a melt index of from 6 to 15 dg/min, or from 9 to 12 dg/min.

Abstract: A novel multi-layer stretch film comprising at least 3 layers and having excellent mechanical properties and stretch film performance, comprising at least one outer or skin layer that has little or no cling or blocking characteristics in an unstretched state, but has substantial blocking characteristics when stretched. The stretch wrap films of the present invention have little or no unwind noise when removed from a stretch wrap film roll.

Abstract: Disclosed and claimed are prodrugs activated by catalytic proteins, such as enzymes and catalytic antibodies. The invention comprehends such prodrugs, as well as haptens, to elicit catalytic antibodies to activate the prodrugs. The prodrugs are useful as cytotoxic chemotherapeutic agents; e.g., as antitumor agents.

Abstract: Lactone copolymers are disclosed which are polymerized from a first lactone monomer and a second amorphous monomer which is effective to suppress the crystallization of the copolymer. It is disclosed that suppression of the crystallization can provide enhanced mechanical properties in films made from the copolymers. As a result, films prepared from the copolymers of the present invention can have properties rendering them suitable for use as biodegradable trash bags as well as for other uses.

Abstract: Condensation copolymers are disclosed which are polymerized from a first monomer which is capable of polymerization by condensation polymerization, e.g., ring opening lactone polymerization, and a second monomer which is effective to suppress the crystallization of the copolymer. It is disclosed that suppression of the crystallization can provide enhanced mechanical properties in films made from the copolymers. As a result, films prepared from the copolymers of the present invention can have properties rendering them suitable for use as biodegradable trash bags as well as for other uses.

Abstract: Prodrugs that are activated by and conjugated to a catalytic antibody conjugated to a moiety that binds to a tumor cell population are provided.

Abstract: The present invention relates to compounds containing an anthracyclinone group such as doxorubicin, daunorubicin or a derivative thereof. The compounds of the invention also contain ester, glycoside or glucuronide structures which are hydrolyzed by the corresponding esterase, glycosidase or glucuronidase. These compounds possess potent cytotoxic activity which is developed after the hydrolysis of the ester or glycoside group of the compound and are effective in the inhibition of tumor cells and bacterial growth after activation.

Abstract: Disclosed and claimed are methods for selecting a recombinant virus, phage or cell expressing a catalytic antibody or catalytic portion thereof, or for selecting catalytic activity by a moiety. The method employs reaction-based selection for catalytic activity. The method can also be used to concentrate (increase the proportion of catalytic to non-catalytic moieties) a sample containing a catalytic moiety or viruses, phages or cells expressing a catalytic moiety. The selection or concentrating can be by employing a mechanism-based inhibitor, catalysis-accelerated movement, surface binding, changes in enthalpic component of binding as a function of temperature, or changes in binding by competition, or combinations thereof. The invention also comprehends a method for producing a recombinant virus or a cell-line expressing a catalytic moiety such as a catalytic antibody or catalytic portion thereof; and, this method can include infecting a suitable host with viruses which are screened for the expression.

Abstract: Disclosed and claimed are methods for selecting a recombinant virus, phage or cell expressing a catalytic antibody or catalytic portion thereof, or for selecting catalytic activity by a moiety. The method employs reaction-based selection for catalytic activity. The method can also be used to concentrate (increase the proportion of catalytic to non-catalytic moieties) a sample containing a catalytic moiety or viruses, phages or cells expressing a catalytic moiety. The selection or concentrating can be by employing a mechanism-based inhibitor, catalysis-accelerated movement, surface binding, changes in enthalpic component of binding as a function of temperature, or changes in binding by competition, or combinations thereof. The invention also comprehends a method for producing a recombinant virus or a cell-line expressing a catalytic moiety such as a catalytic antibody or catalytic portion thereof; and, this method can include infecting a suitable host with viruses which are screened for the expression.

Abstract: A spacecraft platform essentially having two or more panels hinged at the base and contained for launch in a fairing. The panels are hinged and latched in an open deployment and bear, for example, a SAR antenna or an interferometer. The rear faces of the panels are provided with stiffening ribs, webs and struts and carry elements of the payload module and service module which are normally separate structures on a conventional satellite.