Abstract: A process for filtering a fluid is provided. The process includes providing a filtration cell having a filter membrane, a base configured to receive filtrate passing through the membrane, and a flow channel open to the filter membrane. A flow of the fluid is provided through the flow channel substantially tangent to the filter membrane in a first direction and a second direction substantially opposing the first direction, whereby the fluid reciprocally flows across the filter membrane. Filtrate passing through the membrane is collected. A system for filtering a fluid is also provided.

Abstract: Filtration cells capable of direct sampling of a fluid from a container and which may be used for microfiltration of both small and large microvolumes of a fluid to be filtered are provided. Also a process for directly transferring a fluid to be filtered from a container to a filtration cell is described. The filtration cells have one or more reservoirs and are in communication with fluid in a container to be filtered through a piercing instrument connected to a base and support for a reservoir that receives the fluid to be filtered after it passed across a filter membrane. The filtration cell may then be pressurized and vented to allow fluid to be filtered to reciprocally and tangentially pass across a filter membrane between either a container having a fluid to be filtered and a single reservoir for small volume filtrations or between two reservoirs after pressurizing a fluid to be filtered into the reservoirs from a container using a piercing instrument.

Abstract: Filtration cells capable of direct sampling of a fluid from a container and which may be used for microfiltration of both small and large microvolumes of a fluid to be filtered are provided. Also a process for directly transferring a fluid to be filtered from a container to a filtration cell is described. The filtration cells have one or more reservoirs and are in communication with fluid in a container to be filtered through a piercing instrument connected to a base and support for a reservoir that receives the fluid to be filtered after it passed across a filter membrane. The filtration cell may then be pressurized and vented to allow fluid to be filtered to reciprocally and tangentially pass across a filter membrane between either a container having a fluid to be filtered and a single reservoir for small volume filtrations or between two reservoirs after pressurizing a fluid to be filtered into the reservoirs from a container using a piercing instrument.

Abstract: Filtration cells capable of direct sampling of a fluid from a container and which may be used for microfiltration of both small and large microvolumes of a fluid to be filtered are provided Also a process for directly transferring a fluid to be filtered from a container to a filtration cell is described. The filtration cells have one or more reservoirs and are in communication with fluid in a container to be filtered through a piercing instrument connected to a base and support for a reservoir that receives the fluid to be filtered after it passed across a filter membrane. The filtration cell may then be pressurized and vented to allow fluid to be filtered to reciprocally and tangentially pass across a filter membrane between either a container having a fluid to be filtered and a single reservoir for small volume filtrations or between two reservoirs after pressurizing a fluid to be filtered into the reservoirs from a container using a piercing instrument.

Abstract: Filtration cells capable of direct sampling of a fluid from a container and which may be used for microfiltration of both small and large microvolumes of a fluid to be filtered are provided. Also a process for directly transferring a fluid to be filtered from a container to a filtration cell is described. The filtration cells have one or more reservoirs and are in communication with fluid in a container to be filtered through a piercing instrument connected to a base and support for a reservoir that receives the fluid to be filtered after it passed across a filter membrane. The filtration cell may then be pressurized and vented to allow fluid to be filtered to reciprocally and tangentially pass across a filter membrane between either a container having a fluid to be filtered and a single reservoir for small volume filtrations or between two reservoirs after pressurizing a fluid to be filtered into the reservoirs from a container using a piercing instrument.

Abstract: Filtration cells capable of direct sampling of a fluid from a container and which may be used for microfiltration of both small and large microvolumes of a fluid to be filtered are provided. Also a process for directly transferring a fluid to be filtered from a container to a filtration cell is described. The filtration cells have one or more reservoirs and are in communication with fluid in a container to be filtered through a piercing instrument connected to a base and support for a reservoir that receives the fluid to be filtered after it passed across a filter membrane. The filtration cell may then be pressurized and vented to allow fluid to be filtered to reciprocally and tangentially pass across a filter membrane between either a container having a fluid to be filtered and a single reservoir for small volume filtrations or between two reservoirs after pressurizing a fluid to be filtered into the reservoirs from a container using a piercing instrument.