Patents by Inventor David M. Stalker

David M. Stalker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150020233
    Abstract: The invention provides glyphosate tolerant transgenic turfgrass plants, plant material, and seeds that have a specific transformation event. Also provided are assays for detecting the presence of the event. The invention also provides sequences for a variant EPSPS gene and a GAO2X gene, cassettes, and plants comprising the variant EPSPS gene and a GAO2X gene.
    Type: Application
    Filed: July 14, 2014
    Publication date: January 15, 2015
    Inventors: Robert W. HARRIMAN, Lisa LEE, David M. STALKER, Rebecca TORISKY
  • Patent number: 8686225
    Abstract: The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, as well as to methods of making these isolated blood proteins and to therapeutic compositions comprising them.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: April 1, 2014
    Assignee: Ventria Bioscience Inc.
    Inventors: Ning Huang, Raymond L. Rodriguez, Frank E. Hagie, David M. Stalker
  • Publication number: 20120195883
    Abstract: The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, as well as to methods of making these isolated blood proteins and to therapeutic compositions comprising them.
    Type: Application
    Filed: April 17, 2012
    Publication date: August 2, 2012
    Applicant: VENTRIA BIOSCIENCE
    Inventors: NING HUANG, RAYMOND L. RODRIQUEZ, FRANK E. HAGIE, DAVID M. STALKER
  • Patent number: 8158857
    Abstract: The invention is directed to monocot plant seed products comprising human serum albumin, and to methods of making said monocot plant seed products comprising human serum albumin and to therapeutic compositions comprising them.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: April 17, 2012
    Assignee: Ventria Bioscience
    Inventors: Ning Huang, Raymond L. Rodriguez, Frank E. Hagie, David M. Stalker
  • Publication number: 20100183589
    Abstract: The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, and to methods of making these isolated blood proteins and to therapeutic compositions comprising them.
    Type: Application
    Filed: March 31, 2010
    Publication date: July 22, 2010
    Applicant: VENTRIA BIOSCIENCE
    Inventors: Ning Huang, Raymond L. Rodriguez, Frank E. Hagie, David M. Stalker
  • Patent number: 7732678
    Abstract: Novel DNA constructs are provided which may be used as molecular probes or inserted into a plant host to provide for modification of transcription of a DNA sequence of interest in cotton fiber, particularly in very early fiber development. The DNA constructs comprise a cotton fiber transcriptional initiation regulatory region associated with a gene which is expressed in cotton fiber.
    Type: Grant
    Filed: December 3, 1997
    Date of Patent: June 8, 2010
    Assignee: Calgene LLC
    Inventors: Kevin McBride, David M. Stalker, Julie R. Pear, Luis Perez-Grau
  • Publication number: 20100031394
    Abstract: The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, and to methods of making these isolated blood proteins and to therapeutic compositions comprising them.
    Type: Application
    Filed: November 27, 2007
    Publication date: February 4, 2010
    Inventors: Ning Huang, Raymond L. Rodriquez, Frank E. Hagie, David M. Stalker
  • Publication number: 20090258004
    Abstract: The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, and to methods of making these isolated blood proteins and to therapeutic compositions comprising them.
    Type: Application
    Filed: November 27, 2007
    Publication date: October 15, 2009
    Inventors: Ning Huang, Raymond L. Rodriquez, Frank E. Hagie, David M. Stalker
  • Patent number: 7304208
    Abstract: A method of producing human serum albumin (HSA) in monocot plant seeds, by transforming a monocot plant cell with a chimeric gene containing a promoter from the gene of a maturation-specific monocot plant storage protein, a first DNA sequence operably linked to the promoter and encoding a signal sequence, and a second DNA sequence linked in translation frame with the first DNA sequence and encoding HSA, where the first DNA sequence and the second DNA sequence together encode a fusion protein containing an N-terminal signal sequence and the HSA; growing a monocot plant from the transformed monocot plant cell for a time sufficient to produce seeds containing the HSA; and harvesting the seeds from the plant.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: December 4, 2007
    Assignee: Ventria Bioscience
    Inventors: Ning Huang, Raymond L. Rodriquez, Frank E. Hagie, David M. Stalker
  • Publication number: 20030221223
    Abstract: The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, and to methods of making these isolated blood proteins and to therapeutic compositions comprising them.
    Type: Application
    Filed: April 11, 2003
    Publication date: November 27, 2003
    Inventors: Ning Huang, Raymond L. Rodriquez, Frank E. Hagie, David M. Stalker
  • Publication number: 20030177521
    Abstract: A method is provided for transforming solanaceous plants to express DNA sequences interest from the plant cell plastid. The improved method allows the transformation of solanaceous plant tissue which is not obtained from tobacco with DNA constructs. Such DNA constructs comprise, in the 5′ to 3′ direction of transcription, a promoter region functional in a plant plastid and a DNA sequence of interest. The method can be utilized in the transformation of solanaceous plants, such as potato and petunia. The invention further provides constructs and methods for the expression of green fluorescent protein from the plant cell plastid.
    Type: Application
    Filed: February 26, 2003
    Publication date: September 18, 2003
    Inventors: Narender S. Nehra, David J. Schaaf, Vladimir Sidorov, David M. Stalker, Guangning Ye
  • Patent number: 6576818
    Abstract: Provided are two plant cDNA clones that are homologs of the bacterial CelA genes that encode the catalytic subunit of cellulose synthase, derived from cotton (Gossypium hirsutum). Also provided are genomic promoter regions to these encoding regions to cellulose synthase. Methods for using cellulose synthase in cotton fiber and wood quality modification are also provided.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: June 10, 2003
    Assignee: Calgene LLC
    Inventors: David M. Stalker, Julie R. Pear, Deborah Delmer
  • Publication number: 20030106089
    Abstract: Novel DNA constructs are provided which may be used as molecular probes or inserted into a plant host to provide for modification of transcription of a DNA sequence of interest in cotton fiber, particularly in very early fiber development. The DNA constructs comprise a cotton fiber transcriptional initiation regulatory region associated with a gene which is expressed in cotton fiber.
    Type: Application
    Filed: October 31, 2002
    Publication date: June 5, 2003
    Inventors: Kevin McBride, David M. Stalker, Julie R. Pear, Luis Perez-Grau
  • Patent number: 6566586
    Abstract: Provided is a cotton (Gossypium hirsutum) promoter region from an expansin gene expressed in developing fiber.
    Type: Grant
    Filed: January 7, 1998
    Date of Patent: May 20, 2003
    Assignee: Calgene LLC
    Inventors: David M. Stalker, Julie R. Pear
  • Patent number: 6541682
    Abstract: A method is provided for transforming solanaceous plants to express DNA sequences interest from the plant cell plastid. The improved method allows the transformation of solanaceous plant tissue which is not obtained from tobacco with DNA constructs. Such DNA constructs comprise, in the 5′ to 3′ direction of transcription, a promoter region functional in a plant plastid and a DNA sequence of interest. The method can be utilized in the transformation of solanaceous plants, such as potato and petunia. The invention further provides constructs and methods for the expression of green fluorescent protein from the plant cell plastid.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: April 1, 2003
    Assignee: Calgene LLC
    Inventors: Narender S. Nehra, David J. Schaaf, Vladimir Sidorov, David M. Stalker, Guangning Ye
  • Patent number: 6538181
    Abstract: The present invention is directed to the modification of reserve polysaccharides in plants. Specifically, it has been found that host plants can be successfully transformed with a nucleic acid sequence capable of expressing a chimeric reserve polysaccharide modification enzyme gene sequence which will synthesize novel reserve polysaccharides in plants or convert the transformed plant's endogenous starch reserves to novel starch degradation products.
    Type: Grant
    Filed: August 26, 1999
    Date of Patent: March 25, 2003
    Assignee: Calgene LLC
    Inventors: David M. Stalker, Christine K. Shewmaker, Janette V. Oakes
  • Patent number: 6512162
    Abstract: Constructs and methods are provided for expressing peptides derived from eukaryotic organisms in plant plastids. Constructs have a promoter functional in a plant plastid, a DNA sequence encoding a peptide derived from an eukaryotic organism and a transcription termination region. Other elements include a selectable marker for selection of plant cells comprising a plastid expressing the marker and DNA regions of homology to the genome of the plastid and optionally a ribosome binding site joined to the promoter. By methods using such constructs high levels of eukaryotic peptides, such as mammalian proteins, are produced in a plant cell by growing plant cells under conditions whereby the DNA encoding sequences re expressed to produce eukaryotic peptide in said plastid.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: January 28, 2003
    Assignee: Calgene LLC
    Inventors: Kevin E. McBride, Narender Nehra, Douglas A. Russell, David M. Stalker, Jeffrey M. Staub
  • Patent number: 6492578
    Abstract: Provided are constructs and methods for expressing herbicide tolerance genes in plastids of plant cells. Constructs include the components of a promoter functional in a plant plastid, a DNA sequence which is capable of conferring tolerance in a plant cell to at least one herbicide compound when said DNA sequence is transcribed in plastids of said plant cell and a transcription termination region. Herbicide tolerance is produced by transforming plastids with the constructs of the invention and growing plant cells comprising the transformed plastids under conditions wherein the DNA sequence is transcribed and plant plastids and cells containing the plastids are rendered tolerant to applications of at least one herbicide compound.
    Type: Grant
    Filed: July 10, 1999
    Date of Patent: December 10, 2002
    Assignee: Calgene LLC
    Inventors: Jeffrey M. Staub, Peter Hajdukiewicz, Kevin E. McBride, Narender Nehra, David J. Schaaf, David M. Stalker, Guangning Ye
  • Publication number: 20020129401
    Abstract: Provided are two plant cDNA clones that are homologs of the bacterial CelA genes that encode the catalytic subunit of cellulose synthase, derived from cotton (Gossypium hirsutum). Also provided are genomic promoter regions to these encoding regions to cellulose synthase. Methods for using cellulose synthase in cotton fiber and wood quality modification are also provided.
    Type: Application
    Filed: April 18, 2001
    Publication date: September 12, 2002
    Inventors: David M. Stalker, Julie R. Pear, Deborah Delmer
  • Publication number: 20020053094
    Abstract: Constructs and methods are provided for expressing peptides derived from eukaryotic organisms in plant plastids. Constructs have a promoter functional in a plant plastid, a DNA sequence encoding a peptide derived from an eukaryotic organism and a transcription termination region. Other elements include a selectable marker for selection of plant cells comprising a plastid expressing the marker and DNA regions of homology to the genome of the plastid and optionally a ribosome binding site joined to the promoter. By methods using such constructs high levels of eukaryotic peptides, such as mammalian proteins, are produced in a plant cell by growing plant cells under conditions whereby the DNA encoding sequences re expressed to produce eukaryotic peptide in said plastid.
    Type: Application
    Filed: July 10, 1998
    Publication date: May 2, 2002
    Inventors: KEVIN E. MCBRIDE, NARENDER NEHRA, DOUGLAS A. RUSSELL, DAVID M. STALKER, JEFFREY M. STAUB