Abstract: The present invention is directed to a platform (e.g., Web-based) that enables basic and clinical research activities by integrating patient characteristics and clinical outcome data with a variety of high-throughput research data in a unified environment. While several rich data repositories for high dimensional research data exist in the public domain, most focus on a single data type and do not support integration across multiple technologies. The present invention in at least one embodiment includes a broad collection of bioinformatics and systems biology tools for analysis and visualization of four major “omics” types: DNA, mRNA, microRNA, and metabolites, as well as next-generation sequencing. The present invention helps facilitate systems medicine by providing easy identification of trends and patterns in integrated datasets and hence facilitate the use of better targeted therapies for cancer.

Abstract: The present invention is directed to a platform (e.g., Web-based) that enables basic and clinical research activities by integrating patient characteristics and clinical outcome data with a variety of high-throughput research data in a unified environment. While several rich data repositories for high dimensional research data exist in the public domain, most focus on a single data type and do not support integration across multiple technologies. The present invention in at least one embodiment includes a broad collection of bioinformatics and systems biology tools for analysis and visualization of four major “omics” types: DNA, mRNA, microRNA, and metabolites, as well as next-generation sequencing. The present invention helps facilitate systems medicine by providing easy identification of trends and patterns in integrated datasets and hence facilitate the use of better targeted therapies for cancer.

Abstract: Nano structures are formed in a glass layer on a substrate by defining a first structure in the glass layer using a low energy radiation exposure, and then defining a second structure in the glass layer for the dynamic layer using a higher energy radiation exposure. The structures are then developed in TMAH. The structures include at least sensors and nano-channels. Densification is performed by converting the structures to SiO2. Further structures are formed by using different energy exposures. One structure is a channel having a porous wall prior to development.

Abstract: Nano structures are formed in a glass layer on a substrate by defining a first structure in the glass layer using a low energy radiation exposure, and then defining a second structure in the glass layer for the dynamic layer using a higher energy radiation exposure. The structures are then developed in TMAH. The structures include at least sensors and nano-channels. Densification is performed by converting the structures to SiO2. Further structures are formed by using different energy exposures. One structure is a channel having a porous wall prior to development.