Patents by Inventor David M. Weller
David M. Weller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9528115Abstract: In exemplary embodiments, the invention provides Pseudomonas fluorescens 2-79 strains having pyrrolnitrin biosynthetic genes for biocontrol of soilborne diseases.Type: GrantFiled: March 13, 2014Date of Patent: December 27, 2016Assignees: The United States of America, as represented by The Secretary of Agriculture, Washington State UniversityInventors: David M Weller, Linda S Thomashow, Dmitri V Mavrodi, Mingming Yang, Jibin Zhang
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Patent number: 7419812Abstract: Th invention is directed to nucleic acid sequences which encode polypeptides having PhzO activity, namely, the ability to convert phenazine-1-carboxylic acid to a 2-hydroxylated phenazine, and isolated polypeptides having this activity. The invention is also directed to recombinant nucleic acid molecules, vectors, and host cells including the nucleic acid sequences as well as methods for producing and using the polypeptides, including expression in bacterial or plant cells to inhibit fungal pathogens.Type: GrantFiled: March 26, 2004Date of Patent: September 2, 2008Assignees: The United States of America as represented by the Secretary of Agriculture, Washington State University Research FoundationInventors: Linda S. Thomashow, Shannon M. Delaney, Dmitri V. Mavrodi, David M. Weller
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Patent number: 7189547Abstract: Th invention is directed to nucleic acid sequences which encode polypeptides having PhzO activity, namely, the ability to convert phenazine-1-carboxylic acid to a 2-hydroxylated phenazine, and isolated polypeptides having this activity. The invention is also directed to recombinant nucleic acid molecules, vectors, and host cells including the nucleic acid sequences as well as methods for producing and using the polypeptides, including expression in bacterial or plant cells to inhibit fungal pathogens.Type: GrantFiled: March 26, 2004Date of Patent: March 13, 2007Assignees: The United States of America as represented by the Secretary of Agriculture, Washington State University Research FoundationInventors: Linda S. Thomashow, Shannon M. Delaney, Dmitri V. Mavrodi, David M. Weller
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Publication number: 20040158890Abstract: The invention is directed to nucleic acid sequences which encode polypeptides having PhzO activity, namely, the ability to convert phenazine-1-carboxylic acid to a 2-hydroxylated phenazine, and isolated polypeptides having this activity. The invention is also directed to recombinant nucleic acid molecules, vectors, and host cells including the nucleic acid sequences as well as methods for producing and using the polypeptides, including expression in bacterial or plant cells to inhibit fungal pathogens.Type: ApplicationFiled: March 26, 2004Publication date: August 12, 2004Inventors: Linda S. Thomashow, Shannon M. Delaney, Dmitri V. Mavrodi, David M. Weller
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Patent number: 6737260Abstract: The invention is directed to nucleic acid sequences which encode polypeptides having PhzO activity, namely, the ability to convert phenazine-1-carboxylic acid to a 2-hydroxylated phenazine, and isolated polypeptides having this activity. The invention is also directed to recombinant nucleic acid molecules, vectors, and host cells including the nucleic acid sequences as well as methods for producing and using the polypeptides, including expression in bacterial or plant cells to inhibit fungal pathogens.Type: GrantFiled: September 27, 2001Date of Patent: May 18, 2004Assignees: The United States of America, as represented by the Secretary of Agriculture, Washington State University Research FoundationInventors: Linda S. Thomashow, Shannon M. Delaney, Dmitri V. Mavrodi, David M. Weller
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Patent number: 6447770Abstract: Fluorescent Pseudomonas spp. are described which are effective for the control of diseases caused by the soil-borne fungus, Gaeumannomyces graminis (Gg), such as take-all, in small grain crops or turf grass. The subject biocontrol strains have a unique genotype as shown by a characteristic banding pattern, and exhibit root-colonizing ability which is characterized by both higher population density on roots and extended colonizing activity compared to known Gg-suppressive strains. A further property is the ability of a strain to duplicate the level of biocontrol obtained naturally in a take-all decline soil. Methods for isolation and identification of the strains and their use to control diseases caused by Gg are provided. In particular, strains of P. fluorescens NRRL B-21806 and NRRL B-21807.Type: GrantFiled: September 14, 1999Date of Patent: September 10, 2002Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Jos M. Raaijmakers, David M. Weller, Linda S. Thomashow, R. James Cook
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Patent number: 6277625Abstract: Transgenic fluorescent Pseudomonas spp. are described which have a biosynthetic locus which encodes for the production of the antibiotic phenazine-1-carboxylic acid stably introduced into the genome, have a locus which encodes for the production of the antibiotic 2,4-diacetylphloroglucinol, and are effective for control of diseases caused by the soil-borne fungus, Rhizoctonia. Strains are also described which control diseases caused by Gaeumannomyces graminis or Pythium, in addition to Rhizoctonia, or have the ability to control all three diseases.Type: GrantFiled: December 18, 1997Date of Patent: August 21, 2001Assignees: The United States of America as represented by the Secretary of Agriculture, Washington State University Research FoundationInventors: Zhengyu Huang, Linda S. Thomashow, Dmitri V. Mavrodi, Jos M. Raaijmakers, David M. Weller, R. James Cook
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Patent number: 6051383Abstract: DNA sequences which function specifically in the synthesis of 2,4-diacetylphloroglucinol (Phl) are described. The sequences include phl genes which encode phl gene proteins and coding and regulatory sequences for production of Phl as well as sequences containing phl genes, which sequences have the capability of conferring or enhancing Phl biosynthetic capability in bacterial strains. The transformed strains are useful as biocontrol agents against fungal pathogens.Type: GrantFiled: February 17, 1999Date of Patent: April 18, 2000Assignees: The United States of America as represented by the Secretary of Agriculture, Washington State University Research FoundationInventors: Linda S. Thomashow, Mahalaxmi Bangera, David M. Weller, R. James Cook
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Patent number: 5972689Abstract: Methods and products useful to simultaneously control the root diseases caused by Gaeumannomyces graminis, Rhizoctonia, and Pythium in crops susceptible to these root diseases are described. These include a method to identify seed-treatment products for potential to simultaneously control the three kinds of root diseases; Bacillus strains having activity against the three kinds of root diseases and methods of obtaining the same, and compositions comprising a fungicide and a Bacillus strain having activity against the three kinds of root diseases, which compositions are useful for field control of the combination of the three kinds of root diseases.Type: GrantFiled: January 24, 1997Date of Patent: October 26, 1999Assignees: The United States of America as represented by the Secretary of Agriculture, Washington State University Research FoundationInventors: R. James Cook, David M. Weller, Dal-Soo Kim, Linda S. Thomashow
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Patent number: 5955298Abstract: DNA sequences which function specifically in the synthesis of 2,4-diacetylphloroglucinol (Phl) are described. The sequences include phl genes which encode phl gene proteins and coding and regulatory sequences for production of Phl as well as sequences containing phl genes, which sequences have the capability of conferring or enhancing Phl biosynthetic capability in bacterial strains. The transformed strains are useful as biocontrol agents against fungal pathogens.Type: GrantFiled: June 26, 1995Date of Patent: September 21, 1999Assignees: The United States of America as represented by the Secretary of Agriculture, Washington State University Research FoundationInventors: Linda S. Thomashow, Mahalaxmi Bangera, David M. Weller, R. James Cook
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Patent number: 4647533Abstract: A method for screening bacteria to select strains which will suppress Pythium spp. in small grain crops under field conditions and a method for applying field-suppressive bacteria to suppress Pythium spp. in a commercial setting are described. Four Pseudomonas strains which passed the screen test are disclosed.Type: GrantFiled: September 14, 1984Date of Patent: March 3, 1987Assignee: The United States of America as represented by the Secretary of AgricultureInventors: David M. Weller, R. James Cook, J. Ole Becker
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Patent number: 4456684Abstract: A method for screening bacteria to select strains which will suppress diseases caused by the fungus Gaeumannomyces graminis (Gg) under field conditions and a method for applying field-suppressive bacteria to suppress Gg in a commercial setting. Four fluorescens Pseudomonas strains are disclosed which are effective in suppressing take-all in wheat.Type: GrantFiled: September 8, 1982Date of Patent: June 26, 1984Assignee: The United States of America as represented by the Secretary of AgricultureInventors: David M. Weller, R. James Cook, Henry T. Wilkinson