Abstract: Systems and methods related to communication with and control of network-enabled water devices and sensors of various water systems are disclosed. Such water systems may include water filtration systems, water reclamation systems, sump pump systems, pool or spa systems, water softening systems, and plumbing systems. Such water devices may include chemical controllers, smart valves, pool pumps, sump pumps, water softeners, residential appliances, and manifolds. Such sensor devices may include flow meters, splash detectors, motion sensors, moisture sensors, humidity sensors, chemical sensors, water level sensors, pressure sensors, and cameras. Data received from network-enabled water devices and sensors may be processed at a remote server or a local controller, which may cause corresponding alerts or maintenance requests to be sent to one or more user devices or service providers or may automatically control one or more of the water devices and sensors based on analysis of the data.

Abstract: Systems and methods are provided, which relate to identification, troubleshooting, and maintenance/repair of water systems and water devices within such systems. A given water device may include an identifier which may be captured by an installation device when attempting to install the water device and sent to a remote server. The remote server may identify the water device and provide installation support, registration, and/or configuration of the water device. Configuration of the water device may be performed based on configurations of other highly-performing water devices that are similar to the water device, as identified by the server. Problem signatures associated with known possible problems that may arise within a water device may be generated and stored in memory, then may be referenced against real-time device operation data and/or configuration data of the water device in order to diagnose and recommend remediation of problems with the water device.

Abstract: A pumping system including a pump, a motor coupled to the pump, an automation system, and a pump controller located remotely from the automation system. The pump controller is coupled to at least one pump and the motor, and the pump controller is in digital communication with the motor, the automation system, and at least one auxiliary device. The pump controller transmits data to, and receives data from, the automation system and at least one auxiliary device over at least one communication link and operates the motor based on information entered into the automation system and received from the automation system. The pump controller selectively alters an operation of the motor based on the information received from one of the automation system or parameters received from the at least one auxiliary device.

Abstract: An auxiliary device control system for a pool or spa. The auxiliary device control system includes a control system with a user interface, a pump coupled to a swimming pool and a motor coupled to the pump, a filter arrangement, a heater, a water dispersion device, a chlorinator having a chlorinator communication panel, and a lighting device. The pump has an onboard pump controller. The heater has a heater communication panel. The control system is configured to be communicatively coupled to the onboard pump controller, the heater communication panel, the water dispersion device, the chlorinator communication panel, and the lighting device. The user interface includes an LCD display configured to receive input parameters associated with the pump, the heater, the water dispersion device, the chlorinator, the lighting device, and a vacuum.

Abstract: A system includes a motor and a control system operating as a master controller with respect to at least one function, the control system including an automation system with a user interface having a display connected to the automation system. A controller is located remotely from the control system and coupled to a pump or the motor. The controller operating as a slave controller with respect to the at least one function when connected to the control system. The controller is in communication with the motor and the control system, and transmits information to and receives information from the control system over at least one communication link. The controller operates independently to control the motor when disconnected from the control system.

Abstract: Systems and methods are provided for the control of pool/spa device circuits. A control system may control such circuits in response to command data received from local or remote client devices. Feature circuits and light groups may be defined via a user interface to include a group of pool/spa device circuits or light circuits, respectively. Activating a feature circuit may involve performing an associated logic function. Multiple feature circuits may be assigned to a feature circuit group which, when activated, may activate all feature circuits assigned to the feature group. The control system may control the performance of freeze protection and automatic cleaner functions, and may control light circuits to synchronized, color-changing light effects. Commands may be issued to the control system and system data may be stored and retrieved from a remote database via web servers, web application programming interface servers, and/or inter-server communication buses.

Abstract: A pumping system for moving water of a swimming pool includes a water pump, a variable speed motor, and an arrangement for controlling the variable speed motor. The pumping system further includes an auxiliary device operably connected to the arrangement for controlling, which is capable of receiving a parameter from the auxiliary device. The arrangement for controlling is capable of independently controlling the variable speed motor without receipt of a parameter from the auxiliary device. In addition or alternatively, the arrangement for controlling is operable to selectively alter operation of the motor based upon the parameter.

Abstract: A system for determining the health and wellness of an individual user, the said system comprising a measuring device configured to measure and calculate (a) nutritional value of food items consumed, and (b) certain physical activities of the user, wherein the measuring device calculates and displays the weight gain or weight loss.

Abstract: A pumping system for moving water of a swimming pool includes a water pump, a variable speed motor, and an arrangement for controlling the variable speed motor. The pumping system further includes an auxiliary device operably connected to the arrangement for controlling, and an arrangement for providing two-way communication between the arrangement for controlling and the auxiliary device. The arrangement for controlling is capable of receiving a parameter from the auxiliary device through the arrangement for providing two-way communication. In one example, the arrangement for controlling is capable of independently controlling the variable speed motor without receipt of a parameter from the auxiliary device. In addition or alternatively, the arrangement for controlling is operable to selectively alter operation of the motor based upon the parameter.

Abstract: A pumping system for moving water of a swimming pool includes a water pump, a variable speed motor, and an arrangement for controlling the variable speed motor. The pumping system further includes an auxiliary device operably connected to the arrangement for controlling, and an arrangement for providing two-way communication between the arrangement for controlling and the auxiliary device. The arrangement for controlling is capable of receiving a parameter from the auxiliary device through the arrangement for providing two-way communication. In one example, the arrangement for controlling is capable of independently controlling the variable speed motor without receipt of a parameter from the auxiliary device. In addition or alternatively, the arrangement for controlling is operable to selectively alter operation of the motor based upon the parameter.

Abstract: A pumping system for moving water of a swimming pool includes a water pump, a variable speed motor, and an arrangement for controlling the variable speed motor. The pumping system further includes an auxiliary device operably connected to the arrangement for controlling, and an arrangement for providing two-way communication between the arrangement for controlling and the auxiliary device. The arrangement for controlling is capable of receiving a parameter from the auxiliary device through the arrangement for providing two-way communication. In one example, the arrangement for controlling is capable of independently controlling the variable speed motor without receipt of a parameter from the auxiliary device. In addition or alternatively, the arrangement for controlling is operable to selectively alter operation of the motor based upon the parameter.

Abstract: The present invention relates to the use of roscovitine, or a pharmaceutically acceptable salt thereof, in the preparation of a medicament for treating multiple myeloma.

Abstract: A pumping system for moving water of a swimming pool includes a water pump, a variable speed motor, and an arrangement for controlling the variable speed motor. The pumping system further includes an auxiliary device operably connected to the arrangement for controlling, and an arrangement for providing two-way communication between the arrangement for controlling and the auxiliary device. The arrangement for controlling is capable of receiving a parameter from the auxiliary device through the arrangement for providing two-way communication. In one example, the arrangement for controlling is capable of independently controlling the variable speed motor without receipt of a parameter from the auxiliary device. In addition or alternatively, the arrangement for controlling is operable to selectively alter operation of the motor based upon the parameter.

Abstract: The present invention relates to the use of bisarylsulfonamide compounds of formula I wherein W is a C1-5 branched or unbranched alkyl group or a C2-5 alkenyl group; n is 0 or 1; R1 is H, a C1-8 branched or unbranched alkyl group, a C2-8 alkenyl group, or an aryl or aralkyl group; Ar1 is a substituted thienyl, furyl, pyrrolyl, imidazothiazolyl, thiazolyl, pyridyl or phenyl group; and Ar2 is a substituted phenyl, indolyl or benzoimidazolyl group; in the preparation of a medicament for treating proliferative disorders. Further aspects of the invention relate to compounds of formula I, pharmaceutical compositions thereof, and an assay for determining binding to HDM2.