Patents by Inventor David Madar

David Madar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME
    Publication number: 20080076819
    Abstract: A compound of formula (I): or a pharmaceutically acceptable salt, prodrug, salt of a prodrug, or a combination thereof. Methods of inhibiting 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. Methods of treating non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
    Type: Application
    Filed: April 5, 2007
    Publication date: March 27, 2008
    Applicant: Abbott Laboratories
    Inventors: Vince Yeh, Ravi Kurukulasuriya, David Madar, James Link
  • PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV)
    Publication number: 20070265302
    Abstract: The present invention relates to compounds which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: July 25, 2007
    Publication date: November 15, 2007
    Inventors: David Madar, Stevan Djuric, Melissa Michmerhuizen, Hana Kopecka, Xiaofeng Li, Kenton Longenecker, Zhonghua Pei, Daisy Pireh, Hing Sham, Kent Stewart, Bruce Szezepankiewicz, Paul Wiedeman, Hong Yong
  • Pharmaceutical Compositions as Inhibitors of Dipeptidyl Peptidase-IV (DPP-IV)
    Publication number: 20070238753
    Abstract: The present invention relates to compounds that inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: June 1, 2007
    Publication date: October 11, 2007
    Inventors: David Madar, Stevan Djuric, Melissa Michmerhuizen, Hana Kopecka, Xiaofeng Li, Kenton Longenecker, Zhonghua Pei, Daisy Pireh, Hing Sham, Kent Stewart, Bruce Szczepankiewicz, Paul Wiedeman, Hong Yong
  • Heat-shock protein binders
    Publication number: 20070105862
    Abstract: Compounds which bind to and inhibit the activity of HSP90, compositions containing the compounds and methods of treating diseases that are caused or exascerbated by overexpression of HSP90 are disclosed.
    Type: Application
    Filed: November 6, 2006
    Publication date: May 10, 2007
    Inventors: Milan Bruncko, Steven Elmore, Xiaohong Song, David Madar
  • Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
    Publication number: 20070049596
    Abstract: The present invention relates to compounds, which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II, as well as hyperglycemia, metabolic syndrome, hyperinsulinemia, obesity, atherosclerosis, various immunomodulatory diseases, and other diseases.
    Type: Application
    Filed: August 25, 2006
    Publication date: March 1, 2007
    Inventors: Zhonghua Pei, Thomas Geldern, David Madar, Xiaofeng Li, Fatima Basha, Hong Yong, Kenton Longenecker, Bradley Backes, Andrew Judd, Matthew Mulhern, Kent Stewart
  • Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
    Publication number: 20060264433
    Abstract: The present invention relates to compounds, which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, syndrome X, hyperinsulinemia, obesity, atherosclerosis, various immunomodulatory diseases, and other diseases.
    Type: Application
    Filed: May 23, 2006
    Publication date: November 23, 2006
    Inventors: Bradley Backes, Gregory Hamilton, Hana Kopecka, Chunqiu Lai, Kenton Longenecker, David Madar, Zhonghua Pei, Kent Stewart, Thomas Von Geldern
  • Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
    Publication number: 20050215784
    Abstract: The present invention relates to compounds that inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: January 13, 2005
    Publication date: September 29, 2005
    Inventors: David Madar, Stevan Djuric, Melissa Michmerhuizen, Hana Kopecka, Xiaofeng Li, Kenton Longenecker, Zhonghua Pei, Daisy Pireh, Hing Sham, Kent Stewart, Bruce Szczepankiewicz, Paul Wiedeman, Hong Yong