Patents by Inventor David Magnin

David Magnin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
    Publication number: 20050239839
    Abstract: Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: June 9, 2005
    Publication date: October 27, 2005
    Inventors: Lawrence Hamann, Ashish Khanna, Mark Kirby, David Magnin, Ligaya Simpkins, James Sutton, Jeffrey Robl
  • Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
    Publication number: 20050228021
    Abstract: Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: June 9, 2005
    Publication date: October 13, 2005
    Inventors: Lawrence Hamann, Ashish Khanna, Mark Kirby, David Magnin, Ligaya Simpkins, James Sutton, Jeffrey Robl
  • Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof
    Publication number: 20050090539
    Abstract: Methods and compounds for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV are provided.
    Type: Application
    Filed: November 18, 2003
    Publication date: April 28, 2005
    Inventors: Truc Vu, David Brzozowski, Rita Fox, Jollie Godfrey, Ronald Hanson, Sergei Kolotuchin, John Mazzullo, Ramesh Patel, Jianji Wang, Kwok Wong, Jurong Yu, Jason Zhu, David Magnin, David Augeri, Lawrence Hamann
  • Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
    Publication number: 20050038020
    Abstract: Compounds are provided having the formula (I) wherein: n is 0, 1 or 2; m is 0, 1 or 2; the sum of n+m less then or equal to 2; the dashed bonds forming a cyclopropyl ring can only be present when Y is CH; X is H or CN; Y is CH, CH2, CHF, CF2, O, S, SO, or SO2; and A is adamantyl. Further provided are methods of using such compounds for the treatment of diabetes and related diseases, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: July 27, 2004
    Publication date: February 17, 2005
    Inventors: Lawrence Hamann, Ashish Khanna, Mark Kirby, David Magnin, Ligaya Simpkins, James Sutton, Jeffrey Robl