Patents by Inventor David Malwitz

David Malwitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-PHENOXY-6-ARYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE AND N-ARYL-6-ARYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
    Publication number: 20100015141
    Abstract: The invention relates to 4,6-disubstituted-1H-pyrazolo[3,4-d]pyrimidin-4-amine compounds, including 4-phenoxy-6-aryl-1H-pyrazolo[3,4-d]pyrimidine and N-aryl-6-aryl-1H-pyrazolo[3,4-d]pyrimidin-4-amine compounds of the Formula I: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
    Type: Application
    Filed: July 21, 2009
    Publication date: January 21, 2010
    Applicant: Wyeth
    Inventors: Matthew Gregory Bursavich, Pawel Wojciech Nowak, David Malwitz, Sabrina Lombardi, Adam Matthew Gilbert, Nan Zhang, Semiramis Ayral-Kaloustian, James Thomas Anderson, Natasja Brooijmans
  • 3-SUBSTITUTED-1H-INDOLE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
    Publication number: 20090311217
    Abstract: The invention relates to 3-substituted-1H-indole compounds of the Formula I: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
    Type: Application
    Filed: May 28, 2009
    Publication date: December 17, 2009
    Applicant: Wyeth
    Inventors: Matthew Gregory Bursavich, Nan Zhang, Semiramis Ayral-Kaloustian, James Thomas Anderson, Thai Hiep Nguyen, Sabrina Lombardi, David Malwitz, Natasja Brooijmans, Derek Cecil Cole, Adam Matthew Gilbert, Pawel Wojciech Nowak, Kaapjoo Park, Sasmita Das, Hwei-Ru Tsou, Aranapakam Mudumbai Venkatesan, Mercy Adufa Otteng, Gary Harold Birnberg, Gloria Jean MacEwan
  • PYRAZOLOPYRIMIDINE ANALOGS AND THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS
    Publication number: 20080234262
    Abstract: The present invention relates to Pyrazolopyrimidine Analogs, methods of making Pyrazolopyrimidine Analogs, compositions comprising a Pyrazolopyrimidine Analog, and methods for treating mTOR-related disorders comprising administering to a subject in need thereof an effective amount of a Pyrazolopyrimidine Analog. The invention also relates to treating PI3K-related disorders comprising administering to a subject in need thereof an effective amount of a Pyrazolopyrimidine Analog.
    Type: Application
    Filed: March 18, 2008
    Publication date: September 25, 2008
    Applicant: Wyeth
    Inventors: Arie Zask, Pawel Wojciech Nowak, Jeroen Cunera Verheijen, Kevin J. Curran, Joshua Kaplan, David Malwitz, Matthew Gregory Bursavich, Derek Cecil Cole, Semiramis Ayral-Kaloustian, Ker Yu, David James Richard, Mark Lefever