Abstract: Methods for treating prostate cancer, including advanced prostate cancer, in a subject in need thereof, include administering once-daily to the subject, at least 80 mg of N-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-N?-methoxyurea, or a corresponding amount of a pharmaceutically acceptable salt thereof.

Abstract: Methods for treating prostate cancer, including advanced prostate cancer, in a subject in need thereof, include administering once-daily to the subject, at least 80 mg of N-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-N?-methoxyurea, or a corresponding amount of a pharmaceutically acceptable salt thereof.

Abstract: There are provided systems and methods for use with high mast luminaires. For example, there is provided a lighting system that can include a mounting portion and an optical assembly attached to the mounting portion via a rotatable platform. The light system can further include a stop disposed inside the mounting portion, and the stop can be configured to permit a rotation of the optical assembly and to limit the rotation to an angle greater than 360 degrees.

Abstract: Provided is a receptacle for installation within a lighting fixture. The receptacle includes a platform (i) for exposure external to the lighting fixture and (ii) providing connectivity for coupling to an external control device and a base operationally coupled to the platform and including a first set of one or more nodes configured for coupling to a first set of wires.

Abstract: Provided is an insect monitoring device including a tube. An attractor is positioned at an entrance to the tube, and an imaging device is configured for producing data associated with a monitored insect, wherein the data being usable in machine learning.

Abstract: There are provided systems and methods for use with high mast luminaires. For example, there is provided a lighting system that can include a mounting portion and an optical assembly attached to the mounting portion via a rotatable platform. The light system can further include a stop disposed inside the mounting portion, and the stop can be configured to permit a rotation of the optical assembly and to limit the rotation to an angle greater than 360 degrees.

Abstract: There are provided methods and devices for programming a luminaire. For example, there is provided a programming module for use with a luminaire. The programming module includes a connector configured to provide an interface between the programming module and the luminaire via a photo-electric element (PE) socket of the luminaire. The programming module further includes a memory and a processor. When executing instructions included in the memory, the processor is configured to perform operations that include measuring the input power to the luminaire and changing a driver current set point.

Abstract: There is provided a landing platform for mounting on a luminaire, where the landing platform provides an interface to a drone. For example, there is provided a landing platform for a drone, the landing platform being adaptable to mount on a luminaire. The landing platform includes two electrically active portions and an elevated portion. The elevated portion is configured to secure the drone on the landing platform and provide electrical contact between the two electrically active portions and electrical connectors of the drone.

Abstract: In various embodiments, there is provided a luminaire optical system that includes a first optical module and a second optical module. The first optical module includes a first reflective surface configured to output light vectors in a first direction. The second optical module includes a second reflective surface configured to reflect light vectors from the second optical module in a second direction. The first reflective surface and the second reflective surfaces are surfaces of one reflector.

Abstract: There are provided methods and devices for programming a luminaire. For example, there is provided a programming module for use with a luminaire. The programing module includes a connector configured to provide an interface between the programming module and the luminaire via a photo-electric element (PE) socket of the luminaire. The programming module further includes a memory and a processor. When executing instructions included in the memory, the processor is configured to perform operations that include measuring the input power to the luminaire and changing a driver current set point.

Abstract: In various embodiments, there is provided a luminaire optical system that includes a first optical module and a second optical module. The first optical module includes a first reflective surface configured to output light vectors in a first direction. The second optical module includes a second reflective surface configured to reflect light vectors from the second optical module in a second direction. The first reflective surface and the second reflective surfaces are surfaces of one reflector.

Abstract: The present invention relates to supported polycrystalline diamond compact cutters (PDC cutters) made under high temperature, high pressure (HT/HP) processing conditions, and more particularly to supported PDC cutters having non-planar cutting surfaces. More specifically, the present invention is for an oriented PDC cutter wherein chips and debris are funneled away from the cutting edge by a raised top surface of the polycrystalline diamond layer (PCD layer). The redirection of the debris is achieved by the creation of high and low regions on the PCD layer, of which there can be a variety of different surface geometry's. Thus, an object of the present invention is to provide a PDC cutter with improved performance through channeling debris away from its cutting edge.

Abstract: The present invention relates to a novel domed polycrystalline diamond cutting element wherein a hemispherical diamond layer is bonded to a tungsten carbide substrate, commonly referred to as a tungsten carbide stud. Broadly, the inventive cutting element includes a metal carbide stud having a proximal end adapted to be placed into a drill bit and a distal end portion. A layer of cutting polycrystalline abrasive material disposed over said distal end portion such that an annulus of metal carbide adjacent and above said drill bit is not covered by said abrasive material layer. The geometry of the diamond cutting element provides control of interfacial stresses and reduces fabrication costs. The diamond cutting element may contain a pattern of ridges or bumps integrally formed in the abrasive layer which ridges are designed to cause high localized stresses in the rock, thus starting a crack. By initiating cracks in localized areas, the crushing action could be performed with less force.

Abstract: A multiply accumulate circuit (600) includes a multiply accumulate reduction circuit (527) that generates P current accumulated operands during an iteration. P operand registers (582) are coupled to the multiply accumulate reduction circuit (527). A corresponding one of the P current accumulated operands is stored in each of the P operand registers (582) in place of one of the P partial accumulated operands in response to the iteration. Each of P feedback paths (593) couples one of P outputs of the P operand registers (582) to a corresponding one of P feedback inputs of the multiply accumulate reduction circuit (527). An adder (561) that is coupled to the P outputs through isolation circuits (570) generates an output (551) in N iterations that is a sum of N products, each being a product of one of a series of N multipliers and one of a series of N multiplicands.

Abstract: This invention relates to a novel domed polycrystalline diamond cutting element wherein a hemispherical diamond layer is bonded to a tungsten carbide substrate, commonly referred to as a tungsten carbide stud. Broadly, a pattern of ridges or bumps is integrally formed in the abrasive layer which ridges are designed to cause high localized stresses in the rock, thus starting a crack. By initiating cracks in localized areas, the crushing action could be performed with less force.

Abstract: An abrasive cutting element comprised of an abrasive cutting layer and a metal substrate wherein the interface therebetween has a tangential chamfer, the plane of which forms an angle of about 5.degree. to about 85.degree. with the plane of the surface of the cylindrical part of the metal substrate. The abrasive cutting layer is preferably diamond or cubic boron nitride and the metal substrate is preferably tungsten carbide.