Patents by Inventor David Mark Meredith

David Mark Meredith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6706515
    Abstract: The invention relates to manipulation of equine herpes virus for use in gene therapy and in particular to modifications of the virus so that it can carry heterologous material and furthermore, preferably, be replication deficient so that the virus cannot replicate in the target tissue.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: March 16, 2004
    Inventors: Alexander Fred Markham, David Mark Meredith
  • Patent number: 6692955
    Abstract: A herpesvirus saimiri (HVS) vector which has inserted therein at least a part of a gene encoding an envelope protein of HIV for use in delivering said protein to a specific cell population such as T cell lymphocytes and/or macrophages. The invention also provides a vaccine comprising the recombinant vector.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: February 17, 2004
    Assignee: University of Leeds
    Inventors: David Mark Meredith, Alexander Fred Markham
  • Publication number: 20030017173
    Abstract: The invention relates to the use of anti-herpetic sensitive viruses in the treatment of diseases and particularly cancer. More specifically, the invention concerns the genetic manipulation of viruses that are susceptible to anti-herpetic agents so as to enhance their sensitivity to said agents and/or reduce their pathogenicity.
    Type: Application
    Filed: September 13, 2002
    Publication date: January 23, 2003
    Inventors: Alexander Fred Markham, David Mark Meredith
  • Publication number: 20020090716
    Abstract: The invention relates to manipulation of equine herpes virus for use in gene therapy and in particular to modifications of the virus so that it can carry heterologous material and furthermore, preferably, be replication deficient so that the virus cannot replicate in the target tissue.
    Type: Application
    Filed: March 18, 2002
    Publication date: July 11, 2002
    Inventors: Alexander Fred Markham, David Mark Meredith
  • Patent number: 6387685
    Abstract: The invention relates to manipulation of equine herpes virus for use in gene therapy and in particular to modifications of the virus so that it can carry heterologous material and furthermore, preferably, be replication deficient so that the virus cannot replicate in the target tissue.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: May 14, 2002
    Assignee: The University of Leeds
    Inventors: Alexander Fred Markham, David Mark Meredith
  • Patent number: 6379967
    Abstract: The invention relates to herpesvirus saimiri viruses that are genetically modified by mutations and/or deleting specific essential and non-essential genes. The essential genes are required in replication of viral genes and are needed for viral proliferation. The non-essential genes can represent sites for the insertion of heterologous genetic material.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: April 30, 2002
    Assignee: The University of Leeds
    Inventors: David Mark Meredith, Alexander Fred Markham