Abstract: The present disclosure relates to a hydraulic power pack arrangement that can be configured in multiple different mounting configurations. The hydraulic power pack arrangement can include a bracket assembly for mounting a hydraulic power pack core assembly and a hydraulic reservoir assembly at a mounting location such as a floor, wall, or ceiling of an aircraft.

Abstract: A road safety barrier installation system that uses a workstation and product support able to be guided by a truck along a road. The product supporter is adapted to receive a store of product such as ground penetrating anchors, posts and barrier strap. The workstation comprises at least one placement robot able robot able to receive and hold a said product, and position the so received and held product in location as part of the array.

Abstract: A roadside crash barrier configured for deflecting errant vehicles towards the road. The barrier comprising at least one tensioned flexible strap comprising a planar face facing the road in use. Compared to prior art systems, the present invention reduces the chances of injury to motorcyclists, as well as being fast and easy to install. A collapsible end anchor for holding the tension of the straps is also described herein, where the end anchor is configured to reduce vehicle rollover should end on impact occur whilst still retaining the effectiveness of the retained road barrier.

Abstract: Described are methods of preparing reduced 3,7-diamino-10H-phenothiazine (DAPTZ) compounds of formula: wherein: R1 and R9 are independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R3NA and R3NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R7NA and R7NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of HX1 and HX2 is independently a protic acid; and pharmaceutically acceptable salts, solvates, and hydrates thereof. These methods are particularly useful for producing stable reduced forms, and with high purity. The stability and purity are especially relevant for pharmaceutical compositions for the treatment of disease. The compounds are useful for treatment of e.g. tauopathies, such as Alzheimer's disease, and also as prodrugs for the corresponding oxidized thioninium drugs.

Abstract: Disclosed herein are systems, methods, and software for providing a platform for complex image data analysis using artificial intelligence and/or machine learning algorithms. One or more subsystems allow for the capturing of user input such as eye gaze and dictation for automated generation of findings. Additional features include quality metric tracking and feedback, and worklist management system and communications queueing.

Abstract: The present disclosure relates to the treatment of pathological conditions, such as cancer, with Antibody Drug Conjugates (ADCs). In particular, the present disclosure relates to administration of ADCs which bind to CD19 (CD19-ADCs).

Abstract: An apparatus and method for manufacturing an elastic composite structure for an absorbent sanitary product includes a bonding unit configured to bond a first web layer to a second web layer via a bond pattern that includes at least one bond line having at least one pair of adjacent bonds. The bonding unit secures an elastic thread within a passage defined by the at least one pair of adjacent bonds. The passage has a cross-sectional area smaller than a cross-sectional area of the elastic thread in a non-tensioned state.

Abstract: A blade assembly includes an adapter board including a lower tool bit attachment portion, terminating in a lower adapter board free end, the lower adapter board free end defining a bottom surface defining a plurality of shank receiving bores. A plurality of bushings are disposed in a corresponding one of the plurality of shank receiving bores.

Abstract: The invention provides a conjugate comprising a biomolecule linked to a fatty acid via a linker wherein the fatty acid has the following Formulae A1, A2 or A3: wherein R1, R2, R3, R4, Ak, n, m and p are defined herein. The invention also relates to a method for manufacturing the conjugate of the invention such as GDF15 conjugate, and its therapeutic uses such as treatment or prevention of metabolic disorders or diseases, type 2 diabetes mellitus, obesity, pancreatitis, dyslipidemia, alcoholic and nonalcoholic fatty liver disease/steatohepatitis and other progressive liver diseases, insulin resistance, hyperinsulinemia, glucose intolerance, hyperglycemia, metabolic syndrome, hypertension, cardiovascular disease, atherosclerosis, peripheral arterial disease, stroke, heart failure, coronary heart disease, diabetic complications (including but not limited to chronic kidney disease), neuropathy, gastroparesis and other metabolic disorders.

Abstract: A removable and replaceable battery pack includes a plurality of battery cells, an outer housing configured to encase the plurality of battery cells, a handle extending from the outer housing configured to be grasped by a user, an electrical connector located on a rear side of the outer housing, and a plurality of MOSFETs configured to control a current output to the electrical connector. The electrical connector includes a plurality of ports and is configured to electrically couple to a battery receptacle connector. Each of the plurality of MOSFETs is thermally coupled to the outer housing.

Abstract: A blast attenuator for blast overpressure has features that allow for blast attenuation and ease of projectile loading from the muzzle of the weapon system. This combination of physical ease of use and blast reduction allows the system to achieve high levels of performance without making significant concessions to operator safety.

Abstract: A roadside crash barrier configured for deflecting errant vehicles towards the road. The barrier comprising at least one tensioned flexible strap comprising a planar face facing the road in use. Compared to prior art systems, the present invention reduces the chances of injury to motorcyclists, as well as being fast and easy to install. A collapsible end anchor for holding the tension of the straps is also described herein, where the end anchor is configured to reduce vehicle rollover should end on impact occur whilst still retaining the effectiveness of the retained road barrier.

Abstract: This disclosure extends to systems, apparatus, and methods for the rapid deployment of a sling or strap on a rifle, firearm, tool, or implement from a storage mode to a deployment mode in a reliable and repeatable manner, while minimizing snagging, binding or tangling during storage or transport. In one exemplary system in accordance with the teachings of the present disclosure, a capture device may include a single closed loop interface adjacent to an open interface. A first strap may be looped through the closed interface and secured therein. Another portion of the sling system, such as a loop of strap or webbing may be secured by tensioning in the open interface to tightly secure the system against the rifle or tool in a secured position. By slightly loosening the loop, the secured portion can exit the open interface rapidly as the sling is deployed.

Abstract: Disclosed are specimen processing systems capable of processing specimens carried on slides. The specimen processing systems comprise opposables having at least one fluid control element. The fluid control elements may be positioned between spacers or gapping elements the opposable edges. The fluid control elements may comprise an edge, such as a beveled edge or a stepped edge, as described herein, and the edge may be continuous or segmented.

Abstract: Insulated winding wires, winding wire articles, and associated formation methods are described. An insulated winding wire may include a conductor and insulation formed around the conductor. In certain embodiments, the insulation may include a first layer including a first parylene material and a second layer including a second parylene material different from the first parylene material. In other embodiments, the insulation may include one or more layers containing parylene formed over base insulation.

Abstract: A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. The specimen processing stations can use the opposables to apply a series of liquids to the specimens. The applied liquid can be moved along the slide using capillary action while the specimen processing stations control the processing temperatures. The applied liquid can be in a fluid-carrying gap. The opposable can contact the slide to vary a cross section of the fluid-carrying gap.

Abstract: A system includes a refrigerant compressor, an electric motor and configured to drive the refrigerant compressor, and a controller. The controller is configured to operate the compressor in a liquid clearing start mode where electrical current through the motor is prevented from exceeding a predetermined current limit for a period of time not to exceed a predetermined period of time, and is configured to operate the compressor in a run mode in response to determining the motor exceeds a predetermined speed threshold at or before expiration of the predetermined period of time, wherein the run mode does not prevent electrical current through the motor from exceeding said predetermined current limit.

Abstract: This disclosure extends to systems, apparatus, and methods for the rapid deployment of a sling or strap on a rifle, firearm, tool, or implement from a storage mode to a deployment mode in a reliable and repeatable manner, while minimizing snagging, binding or tangling during storage or transport. In one exemplary system in accordance with the teachings of the present disclosure, a capture device may include a single closed loop interface adjacent to an open interface. A first strap may be looped through the closed interface and secured therein. Another portion of the sling system, such as a loop of strap or webbing may be secured by tensioning in the open interface to tightly secure the system against the rifle or tool in a secured position. By slightly loosening the loop, the secured portion can exit the open interface rapidly as the sling is deployed.

Abstract: Systems, devices, and methods of an automatic attack testing framework for the security testing of an operational service are disclosed. In an example, such systems, devices, and methods may include operations that: deploy command instructions and a payload for a bot process to a computing device located within a target infrastructure, with the command instructions being selected based on criteria to test a security feature in the target infrastructure with an automated attack action in the bot process, and with the bot process being executed on the computing device and being started with use of the command instructions and the payload; communicate with the computing device to control the automated attack action within the target infrastructure, such that the automated attack action is performed within the bot process; and obtain results of the automated attack action performed within the bot process from the computing device.