Patents by Inventor David Marshall Mann

David Marshall Mann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAR peptide for homing, diagnosis and targeted therapy for pulmonary and fibrotic disorders
    Patent number: 9180161
    Abstract: Disclosed are compositions and methods useful for delivering targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to effect a beneficial therapeutic result. The disclosed targeting is useful for delivering therapeutic and detectable agents to diseased tissue in an animal.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: November 10, 2015
    Assignees: Sanford Burnham Prebys Medical Discovery Institute, Vascular BioSciences
    Inventors: Masanobu Komatsu, David Marshall Mann, Erkki Ruoslahti
  • R-RAS activity in vascular regulation
    Patent number: 8506965
    Abstract: The invention provides means and methods for vascular regulation through enhancement or inhibition of R-Ras activity. The invention specifically provides means and methods for promoting a quiescent state of a vascular cell by providing additional R-Ras activity to the cell. The invention further provides means and methods for diagnosing a condition of vasculature of an individual.
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: August 13, 2013
    Assignees: Vascular BioSciences, Sanford Burnham Medical Research Institute
    Inventors: Masanobu Komatsu, David Marshall Mann, Erkki Ruoslahti
  • CAR PEPTIDE FOR HOMING, DIAGNOSIS & TARGETED THERAPY FOR PULMONARY AND FIBROTIC DISORDERS
    Publication number: 20130196896
    Abstract: Disclosed are compositions and methods useful for delivering targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to effect a beneficial therapeutic result. The disclosed targeting is useful for delivering therapeutic and detectable agents to diseased tissue in an animal.
    Type: Application
    Filed: February 28, 2011
    Publication date: August 1, 2013
    Applicants: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE, VASCULAR BIOSCIENCES, INC.
    Inventors: Masanobu Komatsu, David Marshall Mann, Erkki Ruoslahti
  • R-RAS ACTIVITY IN VASCULAR REGULATION
    Publication number: 20090304765
    Abstract: The invention provides means and methods for vascular regulation through enhancement or inhibition of R-Ras activity. The invention specifically provides means and methods for promoting a quiescent state of a vascular cell by providing additional R-Ras activity to the cell. The invention further provides means and methods for diagnosing a condition of vasculature of an individual.
    Type: Application
    Filed: November 11, 2005
    Publication date: December 10, 2009
    Inventors: Masanobu Komatsu, David Marshall Mann, Erkki Ruoslahti
  • Kit for obtaining an endoarterial biopsy sample
    Patent number: 7491176
    Abstract: A kit for obtaining an endoarterial biopsy sample from a patient including packaging material enclosing one or more kit components; the kit components include instruments use to perform a surgical procedure; and the kit includes separate phase specific packaging parts.
    Type: Grant
    Filed: November 1, 2001
    Date of Patent: February 17, 2009
    Assignee: Vascular BioSciences
    Inventor: David Marshall Mann
  • Kit for obtaining an endoarterial biopsy sample
    Publication number: 20040031721
    Abstract: A kit for obtaining an endoarterial biopsy sample from a patient comprising: (i) packaging material enclosing one or more kit components; (ii) wherein the kit components comprise one or more of the following: a) an endoarterial biopsy catheter; b) Percutaneous Access Needle; c) Short Introducer Sheath with Dilator & Guidewire; d) Floppy Guidewire; e) Endhole Catheter with inflation syringe; f) Stiff Guidewire; g) Flushing Syringes; h) Long Introducer Sheath with Dilator; i) Biopsy specimen removal tool; j) Biopsy Cassettes; k) Specimen Containers; l) Connective Tubing; m) Vacuum Gauges & Canisters; and, n) Vacuum pump.
    Type: Application
    Filed: April 30, 2003
    Publication date: February 19, 2004
    Inventor: David Marshall Mann