Abstract: An apparatus and method for determining stroke volume. The apparatus receives an arterial pressure waveform and is arranged to correct a part of the pressure waveform that relates to a heart beat for an influence of an ectopic heart beat, of atrial fibrillation on the pressure waveform or of changes in the pressure waveform's baseline. The apparatus also comprising means arranged to calculate the stroke volume from the corrected waveform.

Abstract: An apparatus and method for determining stroke volume. The apparatus receives an arterial pressure waveform and is arranged to correct a part of the pressure waveform that relates to a heart beat for an influence of an ectopic heart beat, of atrial fibrillation on the pressure waveform or of changes in the pressure waveform's baseline. The apparatus also comprising means arranged to calculate the stroke volume from the corrected waveform.

Abstract: A method of setting or adjusting a cardiac pacemaker in a patient diagnosed with cardiac asynchrony, which method comprises the steps of: i) implanting cardiac pacing wires into at least the right ventricle and the left ventricle of the heart of the patient, ii) continuously monitoring and recording the cardiac output, nominal stroke volume and/or arterial pressure of the patient on a beat-by-beat basis, iii) continuously monitoring and recording the respiratory cycle of the patient, and iv) adjusting the conduction delay between the electronic impulses to the cardiac pacing wires until a synchronization of respiratory changes with changes in the cardiac output, stroke volume or arterial pressure of the patient is obtained.

Abstract: A method for the measurement of post arteriolar pressure in a patient which is determined from information regarding the blood pressure (BP), systemic vascular resistance (R) and cardiac output (CO) by plotting the regression line for the equation BP=R×Q+c where c is the post arteriolar pressure, and determining the value of c from the regression line.

Abstract: A method for the measurement of post arteriolar pressure in a patient which is determined from information regarding the blood pressure (BP), systemic vascular resistance (R) and cardiac output (CO) by plotting the regression line for the equation BP=R×Q+c where c is the post arteriolar pressure, and determining the value of c from the regression line.

Abstract: A method for the measurement of cardiac output in a patient in which the arterial blood pressure waveform of a patient from a blood pressure monitoring device over a period of time is subjected to various transformations and corrections, including a Fourier analysis in order to obtain the modulus of the first harmonic. The nominal stroke volume is then determined from the first harmonic and data relating to the arterial blood pressure and heart rate. The nominal cardiac output is then obtained from the nominal stroke volume.

Abstract: A method of analyzing a signal representing a physical parameter to obtain information from said signal and to extrapolate information contained in said signal and/or to ignore an interfering component in part of said signal, said signal representing either only a first portion of a skew distribution, or a first portion of a skew distribution and a second portion containing an interfering component, in which the area of a skew distribution, preferably a lognormal distribution is measured. The method is particularly applicable to the measurement of cardiac output. Apparatus for carrying out the method is also disclosed.

Abstract: A method for the measurement of cardiac output in a patient in which the arterial blood pressure waveform of a patient from a blood pressure monitoring device over a period of time is subjected to various transformations and corrections, including autocorrelation, whereby the pulsatility and heart rate of the patient are obtained. The nominal stroke volume is then calculated from the pulsatility and the nominal caridac output obtained by multiplying the stroke volume by the heart rate.