Abstract: Compounds are provided that can exhibit anti-cancer and/or anti-inflammatory properties, in some aspects, methods of treating an inflammatory disease or a hyperproliferative disease, such as cancer, with the compounds are provided.

Abstract: Representative embodiments disclose mechanisms to complete partial natural language questions. Users enter a partial question. The system comprises a plurality of indexes, one index comprising common phrases associated with natural language questions and other indexes comprising short text entries associated with documents, such as document titles. The partial question is used to search one or more of the indexes. The search yields a ranked list of results. The top k entries of the list are selected and one or more language models are created from the top k entries. Each language model comprises n-grams from the top k entries from an index and an associated probability for each n-gram. A question completion generator creates question completion suggestions by matching n-grams with the partial question, removing ungrammatical candidate suggestions, and filtering the remaining suggestions per a filtering criteria. The top N results are returned as suggestions to complete the question.

Abstract: Representative embodiments disclose mechanisms to complete partial natural language questions. Users enter a partial question. The system comprises a plurality of indexes, one index comprising common phrases associated with natural language questions and other indexes comprising short text entries associated with documents, such as document titles. The partial question is used to search one or more of the indexes. The search yields a ranked list of results. The top k entries of the list are selected and one or more language models are created from the top k entries. Each language model comprises n-grams from the top k entries from an index and an associated probability for each n-gram. A question completion generator creates question completion suggestions by matching n-grams with the partial question, removing ungrammatical candidate suggestions, and filtering the remaining suggestions per a filtering criteria. The top N results are returned as suggestions to complete the question.

Abstract: Compounds are provided that can exhibit anti-cancer and/or anti-inflammatory properties, in some aspects, methods of treating an inflammatory disease or a hyperproliferative disease, such as cancer, with the compounds are provided.

Abstract: A wireless transaction processing system that includes a seller account and a buyer account with the buyer having an Internet enabled device that can access the wireless transaction processing system. The wireless transaction processing system, through the Internet enabled device of the buyer enables full processing of transactions without the need for physical cards or an established sales environment. Additionally, the system allows for the direct promotion of products and services to consumers by any entity.

Abstract: A system, method and computer program product that is capable of security monitoring, threat analysis and client notification for a computer system is provided. This Managed Security Service (MSS) includes a log data sensor component providing a log interceptor service. Log data is collected from server and other equipment log activity and processed using a stateful network security policy to detect security threats and generate an appropriate action.

Abstract: A wireless transaction processing system that includes a seller account and a buyer account with the buyer having an Internet enabled device that can access the wireless transaction processing system. The wireless transaction processing system, through the Internet enabled device of the buyer enables full processing of transactions without the need for physical cards or an established sales environment. Additionally, the system allows for the direct promotion of products and services to consumers by any entity.

Abstract: A wireless transaction processing system, comprising a member seller associated with a data that has a machine-readable representation, and a member buyer having at least an Internet enabled device that can access the wireless transaction processing system. The wireless transaction processing system, through the Internet enabled device of the buyer identifies the buyer, including buyer physical location, receives the machine-readable representation of the data, and displays the received data by the Internet enabled device of the buyer. The wireless transaction processing system wirelessly transmits the buyer information (including buyer location information) and received data for verification and approval of transaction between buyer and seller without exchange of confidential information between a buyer and a seller, and without requiring seller specialty equipment.

Abstract: A wireless transaction processing system that includes a seller associated with a transaction data, and a buyer having an Internet enabled device that can access an account associated with the wireless transaction processing system. The wireless transaction processing system, through the Internet enabled device of the buyer enables full processing of transactions without the use of physical cards.

Abstract: Various exemplary embodiments disclose an apparatus and method for generating a database that maps metadata to peer-to-peer (P2P) content and, more particularly, to a database that an Internet Service Provider (ISP) can build to correlate metadata with P2P traffic. The database may collect metadata having a key that uniquely corresponds to particular P2P content. An ISP may use the database to identify malware in P2P files and tag P2P traffic that seeks to exchange material in violation of applicable copyright laws.

Abstract: Compounds and methods useful as inhibitors of c-Kit are presented. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of c-Kit and processes for synthesizing these compounds are also described herein.

Abstract: We disclose methods of synthesizing radiohalidated organic compounds and their use in positron emission tomography (PET) imaging of cancer cells.

Abstract: An embodiment relates generally to a method of testing a mixed signal device. The method includes monitoring multiple parameters of the mixed signal device and scanning the mixed signal device with an optical source. The method also includes forming multiple windows, where each window is assigned to a respective parameter. The method further includes comparing an image from a respective image to a reference image to determine an existence of an anomaly.

Abstract: We disclose methods of synthesizing radiohalidated organic compounds and their use in positron emission tomography (PET) imaging of cancer cells.

Abstract: The present invention concerns compounds and their use to treat cell proliferative diseases such as cancer. In general aspects, compounds of the present invention are tyrphostin-like in structure. Compounds of the present invention, in certain embodiments, display significant potency by causing, for example, inhibition of Stat3 activation, reduction in c-myc protein levels and/or induction of apoptosis in tumor cells. In general aspects, compounds of the present invention induce one or more of these activities at nanomolar concentrations and typically function through a unique mechanism involving the induction of stress granules that bind specific signaling molecules and prevent them from participating in signal transduction and oncogenesis.

Abstract: Various exemplary embodiments disclose an apparatus and method for generating a database that maps metadata to peer-to-peer (P2P) content and, more particularly, to a database that an Internet Service Provider (ISP) can build to correlate metadata with P2P traffic. The database may collect metadata having a key that uniquely corresponds to particular P2P content. An ISP may use the database to identify malware in P2P files and tag P2P traffic that seeks to exchange material in violation of applicable copyright laws.

Abstract: In one embodiment, the present invention relates to a method of treating a cancer characterized by overexpression of cyclic adenosine monophosphate response element-binding protein (CREB) or phosphorylated CREB (p-CREB) by administering to a patient suffering from the cancer a pharmaceutically-effective amount of a composition comprising a compound selected from the group consisting of 2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide, naphthol analogs having the structure (I), wherein R1 is selected from the group consisting of —H, —F, —Cl, —Br, and —I; R2 is selected from the group consisting of —H, —F, —Cl, —Br, —I, —C1-6 alkyl, —C1-6alkenyl, and —C1-6 alkynyl; R3 is selected from the group consisting of —H and —NO2; and R4 is selected from the group consisting of —H, —C1-6 alkyl, —C1-6 alkenyl, —C1-6 alkynyl, —OC1-6 alkyl, —OC1-6 alkenyl, and —OC1-6 alkynyl; and salts and esters thereof.

Abstract: Compositions for inhibiting the catalytic activity of tyrosine kinases comprising compounds represented by Formulas (I), (II), and (III). Methods for treating proliferative diseases comprising administering a therapeutically effective amount of the above compositions.

Abstract: The present invention relates to compounds and methods use as inhibitors of c-Met. Certain compounds of the subject invention have the following structural formula (I). Other compounds of the subject invention have structural formulas as defined herein. Also disclosed herein are pharmaceutical compositions comprising the compounds of the subject invention.

Abstract: A tool is used to split the coils of a key ring so that the key ring can be easily and efficiently placed on a key or other object. In one embodiment the invention includes a pair of guides, such as ribs or slots, incorporated into the bridge of the key ring grip. One rib or slot assists in getting the key ring onto the key and the other rib or slot assists in removing the key ring from the key. Alternatively, the tool could be separate from the key ring bridge and take the form of a plate having a pair of cut-out sections on opposite sides thereof. One cut-out has a sharp leading edge on the top of the plate and the other has a sharp leading edge on the bottom of the plate. A semicircular handle is attached to one side of the plate and assists it further by widening the gap between the coils so that a key can be threaded onto the free end of the key ring.