Patents by Inventor David McConkey

David McConkey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR CHARACTERIZING BLADDER CANCER
    Publication number: 20240229148
    Abstract: The present invention features methods for characterizing mutational profiles in patients with bladder cancer.
    Type: Application
    Filed: November 13, 2023
    Publication date: July 11, 2024
    Applicants: The Broad Institute, Inc., The General Hospital Corporation, Baylor College of Medicine, The Brigham and Women's Hospital, Inc., Northwestern University, The Johns Hopkins University, United States Government as represented by the U.S. Department of Veterans Affairs
    Inventors: Jaegil KIM, Gad GETZ, Seth Paul LERNER, David KWIATKOWSKI, Joshua MEEKS, Joaquim BELLMUNT, David MCCONKEY
  • METHODS OF DETERMINING TREATMENT OUTCOME
    Publication number: 20240076747
    Abstract: Provided herein are methods of determining treatment outcome in a subject having a disease, the method including evaluating RNA expression level of a B cell related gene to determine a B cell gene signature; evaluating RNA expression level of a CD8+ T cell related gene to determine a CD8+ T cell gene signature; analyzing the B cell gene signature and the CD8+ T cell gene signature (B8T gene signature); and determining treatment outcome in a subject based on the B8T gene signature.
    Type: Application
    Filed: March 10, 2022
    Publication date: March 7, 2024
    Inventors: Burles Johnson, Adam Aragaki, David McConkey, Noah Hahn, Jean Hoffman-Censits
  • Methods for characterizing bladder cancer
    Patent number: 11814687
    Abstract: The present invention features methods for characterizing mutational profiles in patients with bladder cancer.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: November 14, 2023
    Assignees: The Broad Institute, Inc., The General Hospital Corporation, Baylor College of Medicine, The Brigham and Women's Hospital, Inc., Northwestern University, The Johns Hopkins University, United States Government as represented by the U.S. Department of Veterans Affairs
    Inventors: Jaegil Kim, Gad Getz, Seth Paul Lerner, David Kwiatkowski, Joshua Meeks, Joaquim Bellmunt, David McConkey
  • COMPOSITIONS AND METHODS FOR CHARACTERIZING BLADDER CANCER
    Publication number: 20200370133
    Abstract: The present invention features methods for characterizing mutational profiles in patients with bladder cancer.
    Type: Application
    Filed: August 7, 2020
    Publication date: November 26, 2020
    Applicants: The Broad Institute, Inc., The General Hospital Corporation, Baylor College of Medicine, The Brigham and Women?s Hospital, Inc., Northwestern University, The Johns Hopkins University, United States Government as represented by the U.S. Department of Veterans Affairs
    Inventors: Jaegil Kim, Gad Getz, Seth Paul Lerner, David Kwiatkowski, Joshua Meeks, Joaquim Bellmunt, David McConkey
  • METHODS OF CHARACTERIZING AND TREATING MOLECULAR SUBSET OF MUSCLE-INVASIVE BLADDER CANCER
    Publication number: 20150292030
    Abstract: The present application discloses a method of diagnostic testing of primary tumors, circulating tumor cells, serum, and urine to detect high-risk bladder cancers. These results have immediate implications for prognostication and the clinical management of muscle-invasive bladder cancer.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 15, 2015
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: David McConkey, Colin Dinney, Bogdan Czerniak, Keith Baggerly, Mai Tran, Woonyoung Choi, Neema Navai, Liana Adam, Arlene Siefker-Radtke, Matthew Wszolek